Background: Diabetic kidney disease (DKD) is driven by oxidative stress, inflammation, and profibrotic signaling, with transforming growth factor-β (TGF-β) as a key mediator. This trial assessed whether adjunct resveratrol improves serum TGF-β, albuminuria, and glomerular filtration rate (GFR) in adults with DKD. Methods: In a double-blind, randomized, placebo-controlled trial (October 2025…
Pendahuluan: Pasien penyakit ginjal kronik (PGK) yang menjalani hemodialisis kronik memiliki risiko tinggi mengalami infeksi laten tuberkulosis (ILTB) akibat kondisi imunokompromais. Defisiensi vitamin D diketahui berperan dalam penurunan respons imun terhadap Mycobacterium tuberculosis. Namun, hubungan antara kadar vitamin D 25(OH) dengan kejadian ILTB pada populasi hemodialisis di Indonesia m…
Latar Belakang: Penyakit ginjal kronik (PGK) merupakan masalah kesehatan dengan beban morbiditas dan mortalitas yang tinggi, terutama pada pasien dengan faktor risiko seperti hipertensi dan diabetes melitus. Pada stadium lanjut, penurunan fungsi ginjal yang progresif sering memerlukan terapi pengganti ginjal berupa hemodialisis. Pemetaan karakteristik pasien hemodialisis diperlukan sebagai dasa…
Background: End-stage renal disease requires patients to undergo long-term hemodialysis, which may lead to psychological impacts, including stress. The duration of hemodialysis is suspected to be associated with stress levels, yet data regarding patients at Dr. Mohammad Hoesin General Hospital Palembang remain limited. This study aims to analyze the relationship between the duration of hemodial…
Introduction: Anemia is a common complication in Chronic Kidney Disease (CKD) patients, particularly those undergoing hemodialysis. This complication contributes to increased morbidity, mortality, and decreased quality of life. This study aims to evaluate the characteristics of anemia in CKD patients undergoing HD at RSUP Dr. Mohammad Hoesin Palembang. Methods: This study was a descriptive cros…
Chronic Kidney Disease (CKD) is kidney organ disorder caused by decreasing kidney function permanently. Interdialytic Weight Gain (IDWG) and malnutrition are common problems in patients undergoing hemodialysis which can have an impact on the patient's quality of life. This study aimed to determine the relationship between Interdialytic Weight Gain (IDWG) and nutritional status with the quality …
Background: Cognitive impairment is common in chronic hemodialysis patients. Approximately 18,8% of 154 hemodialysis patients with cognitive impairment. Lenght of hemodialysis treatment was a factor that· can lead to cognitive impairment. The longer patients had nndergoing hemodialysis, the greater possibility ofside effects such as hypotension, hemolysis and cognitive impairment. This study a…
Dislipidemia adalah kelainan metabolisme lipid yang ditandai dengan peningkatan maupun penurunan komponen lipid dalam plasma. Dislipidemia dapat terjadi pada lebih dari 60% pasien penyakit ginjal kronik (PGK) yang menjalani hemodialisis. Penyakit ginjal kronik dihubungkan dengan meningkatnya kadar trigliserida, menurunnya kadar kolesterol High Density Lipoprotein (HDL) dan bervariasinya (sediki…
Background: Chronic kidney disease is a condition in which there is destruction of the kidneys along with structural or functional abnormalities, with or without decreased glomerular filtration rate for more than 3 months. The common treatment for this condition is hemodialysis, however, it may cause complications, specifically cardiovascular and non-cardiovascular system dysfunctions that can …