Background. Systemic Lupus Erythematosus (SLE) is a chronic multisystem autoimmune disease characterized by the production of autoantibodies and excessive immune activation, resulting in widespread organ damage. Immunosuppressive therapy constitutes a cornerstone in the management of SLE by suppressing abnormal immune responses and preventing further organ injury. The effectiveness of such ther…
Background: Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease that can attack various organ systems in the body. SLE disease occurs due to the formation of autoantibodies which provide an excessive response resulting in the formation of immune complexes. Disease activity in SLE patients can be seen from the severity of the disease. The severity of the disease can be influenced …
Background: Obesity is a condition characterized by the excessive accumulation of body fat, also the reason for insulin resistance, as lipid buildup in the liver triggers an inflammatory process. Inflammatory mediators in the liver are activated by Kupffer cells to produce cytokines pro inflammation. Prevention and management of obesity can be achieved through dietary modification intermittent …
Cutaneous lupus erythematosus is an autoimmune disease that mainly attacks the skin and mucosal tissue. Manifestations of cutaneous lupus erythematosus are very diverse, including the shape and location of lupus lesion. This study is aimed to increase prevention and awareness of cutaneous lupus erythematosus by analyzing prevalence and characteristics of cutaneous lupus erythematosus in Dr. Moh…
Background. Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease which is also known as the "thousand faces" disease because it has a wide range of clinical manifestations as well as a varied course of disease and prognosis. The etiological mechanism of SLE is not fully understood, so there is often a mistake in recognizing lupus, causing delays in the diagnosis and m…
Systemic lupus erythematosus in children has higher disease activity and disease burden than SLE in adults. Clinical manifestations in SLE patients are highly variable, can have different combinations of symptoms and also tend to mimic other medical conditions. The features of early manifestations at disease onset of SLE are very important in early diagnosis and referral. In addition, several i…
Systemic Lupus Erythematosus or Lupus is an autoimmune disease whose sufferers continue to increase every year in Palembang. Despite of lupus being a chronic disease impacting badly physically and psychologically of the sufferer, lupus is still not widely known, it is rare for people to understand or care to provide support for people with lupus. The purpose of this study was to determine the r…