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OPTIMASI DAN KARAKTERISASI DISPERSI PADAT OFLOKSASIN DENGAN VARIASI JUMLAH OF…
Ofloksasin termasuk ke dalam biopharmaceutical classification system (BCS) kelas II dengan kelarutan rendah, yang mengakibatkan bioavailabilitas obat menjadi terbatas. Penelitian ini bertujuan untuk meningkatkan kelarutan ofloksasin dengan memformulasikannya dalam sistem dispersi padat dengan natrium alginat dan kitosan yang digunakan sebagai matriks polimer. Pengembangan formula optimum disper…
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- xix, 169 hlm.; ilus.; tab.; 29 cm.
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- T1694962025
UJI AKTIVITAS ANTIDEPRESAN EKSTRAK ETANOL DAUN SUNGKAI (PERONEMA CANESCENS JA…
The leaves of Sungkai (Peronema canescens Jack) contain secondary metabolites, flavonoids, which have the potential as antidepressant activity. This study aims to determine the effect of ethanol extract of Sungkai leaves on antidepressant activity and its optimal dose. In this study, six groups were divided: the normal group (NaCMC 0,5% without acute stress induction), the negative group (NaCMC…
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- xvi, 90 hlm.; ilus.; tab.; 29 cm.
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- T1694362025
FORMULASI DAN UJI ANTIBAKTERI LOTION EKSTRAK ETANOL AKAR BAJAKAH KUNING (Cosc…
Plants that have the potential as antibacterials to overcome bacteria that cause body odor (Staphylococcus epidermidis) are ethanol extracts of yellow bajakah roots which contain citral. This study aims to make lotions with various concentrations of ethanol extract of yellow bajakah root (0%, 2%, 4%, and 6%) as antibacterial against Staphylococcus epidermidis. The lotion evaluation test include…
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- xix, 113 hlm.; ilus.; tab.; 29 cm.
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- T1690852025
ANALISIS RASIONALITAS TERAPI STROKE ISKEMIK DI RSUD SITI FATIMAH PROVINSI SUM…
Stroke iskemik terjadi akibat penyumbatan arteri serebral yang menghambat aliran darah ke otak, meningkatkan risiko kecacatan dan kematian. Penerapan terapi yang rasional berperan penting dalam efektivitas pengobatan dan pencegahan komplikasi. Penelitian ini bertujuan untuk menganalisis rasionalitas terapi stroke iskemik di RSUD Siti Fatimah Provinsi Sumatera Selatan. Desain penelitian yang dig…
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- xxi, 123 hlm.; ilus.; tab.; 29 cm.
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- T1690332025
STUDI DISPERSI PADAT CEFIXIME DENGAN KOMBINASI KITOSAN DAN VARIASI NATRIUM AL…
Cefixime is a third-generation cephalosporin antibiotic known for its low solubility and permeability. Various technologies have been developed to address this issue, one of which is solid dispersion technology. In this study, chitosan and sodium alginate were used as carrier matrices to produce cefixime solid dispersions. The aim of the study was to evaluate the effect of chitosan and sodium a…
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- xviii, 96 hlm.; ilus.; tab.; 29 cm.
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- T1690842025
UJI AKTIVITAS NANOEMULSI MINYAK CENGKEH DAN CREMOPHOR RH-40 PEMBAWA ASAM USNA…
Lichen is one of the organisms known for its diverse secondary metabolites, one of which is usnic acid. Usnic acid is known to have anti-inflammatory and antibacterial activities to accelerate burn wound healing. This study aims to determine the concentration of clove oil and Cremophor RH-40 from various concentrations to obtain the optimum usnic acid nanoemulsion formula and test its activity …
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- xvii, 23 hlm.; ilus.; tab.; 29 cm.
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- T1690442025
UJI AKTIVITAS ANTIDEPRESAN EKSTRAK ETANOL HERBA SIRIH CINA (Peperomia pelluci…
Ethanol extract of Chinese Betel Herb (Peperomia Pellucida (L.) Kunth) is known to contain secondary metabolites, including flavonoid compounds that are thought to have potential antidepressant activity. This study aims to determine the effect of ethanol extract of Chinese betel herb as an antidepressant and determine the best concentration of ethanol extract of Chinese betel herb. Parameters o…
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- xvii, 111 hlm.; ilus.; tab.; 29 cm.
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- T1690012025
PENGUJIAN EKSTRAK DAN FRAKSI DAUN GELAM (Melaleuca leucadendra L.) SEBAGAI AN…
Pain and inflammation are common health issues experienced by patients. Non-steroidal anti-inflammatory drugs (NSAIDs) are often used to treat these conditions, but they come with undesirable side effects. Traditional medicine using Gelam leaves (Melaleuca leucadendra L.) may offer a promising alternative with potential analgesic and anti-inflammatory properties. Secondary metabolites in Gelam …
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- xviii, 96 hlm., ilus., tab.; 29 cm
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- T1644622025
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