Background. Anaplastic Large Cell Lymphoma (ALCL) is a mature T-cell lymphoma characterized by strong CD30 expression and is classified into ALK-positive and ALK-negative subtypes. Although both subtypes share similar histopathological features, differences in ALK expression are associated with distinct biological behavior, treatment response, and prognosis. International studies have reported …
Health is a basic need that supports people’s daily activities and productivity. Hospitals, as referral health care facilities, are required to provide high-quality services in line with the implementation of the National Health Insurance (JKN) program through BPJS Kesehatan. Various problems such as limited health personnel, service time, attitudes of medical staff, and the quality of facili…
Klebsiella pneumoniae is a Gram-negative bacterium that can cause various infectious diseases, including pneumonia. Throughout its history, this bacterium has developed resistance to antibiotics. K. pneumoniae exhibits various resistance strategies, including enzymatic modification, gene mutations, and increased efflux pumps. The increasing prevalence of resistance each year has become a key fa…
Free radicals are molecules with unpaired electrons that can cause tissue damage through oxidative stress, accelerate aging, and trigger various diseases, including cancer. Antioxidants play an important role in warding off free radicals. Purple sweet potato leaves (Ipomoea batatas L.) are known to contain active compounds such as polyphenols, flavonoids, tannins and triterpenoids which have hi…
Background: Food allergy is one of the most common health problems in children, with prevalence increasing annually. However, many parents often misinterpret their children's symptoms as food allergies, even though food may not necessarily be the cause. Given the rising incidence of food allergies and the misunderstanding among parents, this study aims to determine the prevalence of food allerg…
Background: Pediatric intensive care unit (PICU) patients are in critical condition, requiring a clear understanding of admission indications, treatment priorities, and patient outcomes. Mapping these profiles is important to describe case patterns in the PICU at Dr. Mohammad Hoesin General Hospital in Palembang and to serve as a basis for evaluating and improving service quality. Objective: To…
Background: Hypertensive disorders in pregnancy remain one of the leading causes of maternal and fetal morbidity and mortality worldwide. These conditions may result in serious complications such as preeclampsia, eclampsia, and fetal growth restriction. Calcium requirements increase significantly during the third trimester to support fetal bone mineralization, while calcium deficiency has been …
Background. Breast lymphoma is a blood malignancy that can be seen as a primary tumor (primary breast lymphoma/PBL) or a secondary manifestation of lymphoma that arises from different parts of the body. Although it is rarer than breast cancer (BC), it has a worse prognosis than BC. This study aims to determine the number of cases and distribution of characteristics of breast lymphoma at Dr. Moh…
Background: Pulmonary tuberculosis (TB) is a chronic contagious infection caused by Mycobacterium tuberculosis. Tuberculosis is a public health problem that has become a global challenge. Non-adherence to treatment is one of the biggest obstacles in treating TB in the world, and is the factor that contributes most to treatment failure. The aim of this research is to determine the level of educa…
Introduction: Neonatal sepsis is a clinical syndrome of systemic disease accompanied by bacteremia in infants within the first month of life. Neonatal sepsis is one of the main causes of morbidity and mortality, both in full-term and premature infants. Cases of neonatal sepsis in Indonesia are quite high, including in high-risk groups such as male infants. The purpose of this study was to deter…
Background: Acute coronary syndrome (ACS) is a heart disorder characterized by the sudden decrease of blood supply to the heart due to the narrowing of the coronary blood vessels. Acute coronary syndrome is based on risk factors such as age, gender, and lifestye. An abnormal lipid profile due to an unhealthy lifestyle is also one of the risk factors of acute coronary syndrome. This study aims t…
Background: Short-term memory is a chemical process between neurons in processing and storing information in a small and short duration. Memorizing the Qur'an can induce neuroplasticity through the Long-term Potentiation (LTP) mechanism, thus strengthening synaptic connections that will implement in increasing memory acuity and brain intelligence. This study aims to determine relationship betwe…
Background: Sexual harassment is a serious and widespread human rights violation, encompassing physical, verbal, or psychological acts without the victim's consent, occurring in various contexts such as households, workplaces, and educational institutions. Its impact is severe, including depression and decreased quality of life. Among students, cases of sexual harassment continue to increase, e…
Cervical cancer is the fourth most common cancer in the world, with a total of 569,847 cases and 311,365 deaths in 2018. Cervical cancer ranks as the second-highest cause of death in women . This study aims to determine the prevalence , age distribution , and distribution of histopathology subtypes based on the World Health Organization 2014 classification , the location of metastasis, the rela…
Background: The eyelids in humans have a vital role in protecting the eyes from the external environment and foreign objects. The skin of the eyelids is not only the thinnest skin of the body but also the part that is often exposed to sunlight, in addition the eyelids are also the most sensitive part of the body, making it possible to contract benign or malignant tumors. This study purpose is t…
Acute Kidney Injury (AKI) is a clinical syndrome of sudden decrease in glomerular filtration rate. Several risk factors for pediatric GgGA include sociodemographics, congenital diseases, and renal replacement therapy (RRT). GgGA is often found in hospitalized sick children and is at high risk of death. This study used analytic research with a cross sectional approach. Subjects were taken using …
Background: Gastric malignant tumors are the sixth most common malignancy in the world and the fourth leading cause of cancer death in the world. Approximately 90% of gastric malignant tumor cases originate from the epithelium, namely adenocarcinoma. The etiology and main risk factors for gastric malignant tumors are caused by Helicobacter pylori infection. Symptoms of gastric malignant tumors …
Obesity is a condition characterized by excess body fat, leading to various health issues, including histological changes in organs such as the spleen (lien). This study aims to compare the histological features of the spleen in an obesity mouse model treated with Moringa oleifera leaf extract to investigate its potential effects on obesity-induced histological alterations. This experimental st…
Obesitas merupakan masalah kesehatan global yang berkaitan dengan inflamasi sistemik, termasuk inflamasi lobular pada hati yang memicu perkembangan Non-Alcoholic Fatty Liver Disease (NAFLD). Ekstrak daun kelor (Moringa oleifera) dikenal memiliki efek antioksidan dan antiinflamasi yang potensial untuk menurunkan inflamasi tersebut. Penelitian ini menggunakan desain deskriptif observasional denga…
Low Birth Weight (LBW) is a leading cause of infant mortality and is associated with various long-term complications, such as growth and developmental disorders. Maternal characteristics and behaviors during pregnancy are believed to influence the incidence of LBW. This study aims to explore this relationship. A cross-sectional analytical study was conducted involving 55 mothers who delivered b…
Background: Solid tumors are a major cause of morbidity and mortality in children. The outcomes of pediatric patients with solid tumors are influenced by various factors, including demographic characteristics, nutritional status, perinatal history, socioeconomic conditions, tumor stage, and the type of therapy administered. Data regarding outcomes and associated factors among children with soli…
Background: Chronic kidney disease (CKD) is a global health problem frequently accompanied by anemia, commonly caused by iron deficiency. In patients undergoing chronic hemodialysis, iron deficiency may result from chronic inflammation, repeated blood loss, and impaired iron metabolism. Assessing iron status is essential to reduce morbidity and mortality. Objective: To describe the characterist…
Introduction: Hypospadias is a complex congenital anomaly with a prevalence of 1:250-1:300 births. Glanular-Frenular Collar (GFC) technique emphasizes tissue preservation and formation of near-normal anatomy. This study evaluates the profile and short-term outcomes of hypospadias surgery using GFC by a single operator in two healthcare facilities in Palembang. Methods: A descriptive-analytic qu…
Computer Vision Syndrome (CVS) is a collection of symptoms related to prolonged use of digital devices, such as eye strain, dry eyes, and visual disturbances. CVS is a common health issue, especially among university students who frequently use computers for academic activities. This study aims to determine the incidence and risk factors of CVS among students of the Faculty of Medicine, Sriwija…
Background: Heart valve disease is a structural or functional abnormality of the cardiac valves that can lead to significant hemodynamic disturbances and increased morbidity and mortality. Aortic or mitral valve surgery is the definitive treatment for severe stenosis or regurgitation. Data regarding the profile of patients undergoing heart valve surgery at Mohammad Hoesin Hospital Palembang rem…
Pendahuluan: ST-elevation myocardial infarction (STEMI) merupakan bentuk tersering sindrom koroner akut dengan risiko morbiditas dan mortalitas yang tinggi. Lama rawat inap menjadi salah satu indikator prognosis. Penelitian ini bertujuan untuk membandingkan akurasi skor risiko GRACE dan klasifikasi Killip dalam memprediksi lama rawat inap pada pasien STEMI di RS Mohammad Hoesin Palembang. Metod…
Latar Belakang: Penyakit ginjal kronik (PGK) merupakan masalah kesehatan dengan beban morbiditas dan mortalitas yang tinggi, terutama pada pasien dengan faktor risiko seperti hipertensi dan diabetes melitus. Pada stadium lanjut, penurunan fungsi ginjal yang progresif sering memerlukan terapi pengganti ginjal berupa hemodialisis. Pemetaan karakteristik pasien hemodialisis diperlukan sebagai dasa…
Colorectal cancer is a cancer with increasing prevalence globally. Tumor budding, which characterizes the morphology of tumor invasiveness, is recognized as an important prognostic factor in this type of cancer. Although many studies have been conducted to determine the relationship between the degree of tumor budding with clinical and histopathological characteristics, a clear consensus still …
Background: Antenatal care (ANC) is a series of health services that are essential to support the health of pregnant women and fetuses. The quality of ANC services plays a crucial role in reducing maternal and infant mortality. This study aims to analyze the level of satisfaction of pregnant women with antenatal care at Puskesmas Sekip, Palembang in 2024. Method: This study used a quantitative …
Background. Allergic rhinitis is an inflammatory condition of the nasal mucosa caused by an allergic reaction mediated by IgE after exposure to an allergen. Allergic rhinitis can be detected using the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire and the Score for Allergic Rhinitis (SFAR). The goal was to determine the results of allergic rhinitis screening in s…