Introduction: Cardiovascular disease is the leading cause of morbidity and mortality in chronic haemodialysis patients. Conventional assessment of systolic function using left ventricular ejection fraction (LVEF) is often less sensitive in detecting subclinical myocardial dysfunction that impacts short-term prognosis. Left ventricular Global Longitudinal Strain (GLS) is suspected to be closely …
Background: Sarcopenia is a progressive skeletal muscle disorder characterized by a decline in muscle strength, mass, and physical performance, leading to increased fall risks and reduced quality of life in the elderly. The pathogenesis is driven by "inflammaging," particularly elevated levels of Interleukin 6 (IL-6). Given the rising geriatric population in Palembang, early detection through c…
Background: As people age, the human body undergoes physiological changes, including a progressive reduce of skeletal muscle mass and strength, known as sarcopenia. The diagnosis of sarcopenia is based on calf circumference screening, also measurement of muscle mass, muscle strength, and physical performance. The primary factors contributing to sarcopenia are systemic inflammation and oxidative…
Background Elderly individuals represent a population with a high potential for a decline in the quantity and quality of skeletal muscles, a condition known as sarcopenia. Muscle quantity refers to the reduction in muscle mass, while muscle quality can be assessed through muscle strength and physical performance as age advances. Sarcopenia significantly reduces the ability to perform daily func…
Background: The presence of a malignant pleural effusion (MPE) indicates advanced stage in malignancy, which severely compromises in a poor prognosis. The LENT score has been developed as a prognostic tool for MPE, yet its association with pleural effusion progression and six-month survival has not been thoroughly evaluated, particularly in Indonesia. Methods: This prospective cohort study incl…
Background: Type 2 diabetes mellitus (T2DM) is characterized by hyperglycemia resulting from impaired insulin secretion or insulin resistance, with chronic low-grade inflammation playing a role in its pathogenesis. Diacerein has anti-inflammatory effects and improves insulin sensitivity; however, clinical evidence in Indonesia remains limited. Objective: To evaluate the effect of adding diacere…