Introduction: Sepsis is a life-threatening organ dysfunction, one of the leading cause of morbidity and mortality worldwide, including Indonesia. The rapid progression of the disease and its variable clinical manifestations affect sepsis- related mortality. Biomarker testing, particularly plasma lactate level, plays a vital role as an indicator of tissue hypoxia, a predictor of mortality, and a…
Sepsis is a life-threatening condition that occurs when the body’s immune system fails to respond properly to an infection, leading to organ dysfunction. It remains a significant global health issue, particularly in low- and middle-income countries. This study aimed to examine the distribution of bacterial types and their antibiotic sensitivity patterns in blood cultures from sepsis patients.…
Background: Sepsis is a life-threatening organ dysfunction caused by a disorganized host response to infection. Sepsis is a major cause of morbidity and mortality in the intensive care unit, with a mortality rate in Asia including Indonesia reaching 44.5%. Risk factors that can increase sepsis mortality are age, sex, comorbid diseases, and the installation of mechanical ventilation or RRT in th…
Background: Sepsis is a complex clinical syndrome that results from a harmful or damaging host response to infection. Sepsis ranks at the top 10 leading causes of death in United State. Incidence of sepsis increases every year. Sepsis releases inflammatory mediators and actives of the excess. There are a variety of cytokines that play a role in the inflammatoiy process, the most important, TNF-…