Free radicals are molecules with unpaired electrons that can cause tissue damage through oxidative stress, accelerate aging, and trigger various diseases, including cancer. Antioxidants play an important role in warding off free radicals. Purple sweet potato leaves (Ipomoea batatas L.) are known to contain active compounds such as polyphenols, flavonoids, tannins and triterpenoids which have hi…
Background: Purple sweet potato (Ipomoea batatas L.) is a carbohydrate food other than rice that is rich in antioxidant and anti-inflammatory compounds. There is few scientific research on the use of purple sweet potato as an herbal therapy ingredient to treat fibrosis. The purpose of this study was to determine the efficacy of purple sweet potato extract on reducing serum creatinine levels in …
Latar Belakang: Anemia defisiensi besi adalah suatu penyakit karena kadar pada eritrosit dan hemoglobin di bawah batas normal, berkurangnya kadar eritropoesis pada tubuh, sehingga tubuh mengalami kelemahan dan dapat menganggu aktivitas sehari-hari. Carica papaya atau tanaman papaya dikenal banyak memiliki manfaat sebagai obat tradisional obat hipertensi, malaria, malnutrisi, anemia, Penelitian …
Introduction: Consumable water hygiene problems related to fluoride contamination are becoming an important issue in Indonesia. Indonesia's geographical location has many active mountains causes a lot of fluoride content in mountain air which is often used for consumable water. Fluoride has several impacts on health, one of which is the level effect of blood sugar. The research that has been ca…
Background: Fluoride is one of the minerals that are abundant in nature. WHO has declared the existence of fluorosis endemic areas due to excessive consumption. Fluoride has a neurotoxicity effect and impaired the cognitive function in memory domain. Memory formation is closely related to glutamate and its receptors (NMDA and AMPA). This study aimed to determine the effect of sodium fluoride ex…
Insomnia is a sleep disorder that reduces the quality of life. Insomnia affects the HPA Axis by increasing cortisol levels. Cinnamomum burmannii is a plant that has antiinflammatory and antioxidant activity. This study aims to determine effect of nonpolar fraction of cinnamon on cortisol levels. This study was an in vivo experimental study using a post-test only design and a control group at th…
Background: Tooth extraction is a surgical procedure that can cause injury to the socket. Catfish (Pangasius pangasius) is freshwater fish which its bones can be used because it contains such as collagen and arginine. Collagen and arginine has been reported can increase the number of new blood vessels in the wound healing process. Aim: To determine the effect of catfish bone extract on angiogen…
Background: Insomnia is a sleep disorder that adversely affects health and quality of life. Therapy using GABA-A receptor agonists has a variety of side effects. Cinnamon contains anti-inflammatory and antioxidant compounds. This study aims to determine the effect of cinnamon nonpolar fraction (CNF) on GABA levels. Methods: This study is an experimental study in vivo post-test only with a contr…
Insomnia is a body disorder characterized by decreased sleep quality in the form of difficulty initiating or maintaining sleep. Insomnia is often associated with serotonergic cell death. Cinnamon (Cinnamomum burmannii) is a plant studied to have anti-inflammatory and antioxidant effects. This study aims to determine the efficacy of the nonpolar fraction of cinnamon on serotonin levels. This stu…
There is less scientific research about effect of inducing high doses of folic acid on the kidneys of wistar rats and research on creating animal models of kidney fibrosis. The purpose of this study was to determine the nephrotoxic effect that leads to kidney fibrosis in the induction of high doses of folic acid in wistar rats. In vivo experimental research was carried out in September-October …
Background: Insomnia is a sleep disorder that decreases quality of life and melatonin level due to chronic inflammatory, but the current treatment is still not effective. Cinnamon is rich in anti-inflammatory and antioxidants compounds. This study aims to determine the effect of the cinnamon nonpolar fraction on melatonin levels. Methods: This study is an experimental study in vivo post-test on…
Latar belakang: Diabetes melitus merupakan penyakit metabolik kronik yang dapat disertai manifestasi ulser mulut. Penyembuhan ulser pada DM berlangsung lebih lama karena kondisi hiperglikemia yang menghambat proses inflamasi saat menjadi makrofag antiinflamasi. Kulit ikan patin mengandung asam amino yang dapat mempengaruhi kecepatan dan kualitas penyembuhan luka saat proses inflamasi. Tujuan da…