Diuretics are drugs that can increase the rate of urine formation. Cempedak (Artocarpus champeden) contains phenolic compounds potentially as diuretics. This study aims to determine the diuretic activity of the ethyl acetate fraction of cempedak leaves. The total phenolic level of ethyl acetate of the epoxy leaf is determined using a UV spectrophotometer at a maximum wave rate of 744 nm. The di…