Propionibacterium acne (P. acne) is a group of bacteria that causes acne. P. acne lived by consuming chemical compounds from sweat glands and fat on the skin face. Fluids in acne containspus, red blood cell lysis component and cytokine which is produced by cell’s of body defences. P. acne bacteria hides in that fluids and can proliferate. Most of free molecule of clindamycin can not reach P. …