Introduction: Ventricular Septal Defect (VSD) is the presence of one or more holes in the interventricular septum (IVS). VSD is the most common congenital heart disease (CHD) in children and one of the treatment option is open heart surgery. This research aims to identify the clinical profile of VSD patients who underwent open heart surgery at RSUP Mohammad Hoesin Palembang in period of January…