Background:Malaria was still a cause of morbidity and mortality in infants, children and adults (especially pregnant women), especially in tropical countries such as Indonesia. This study aims to identified the mutation in the DHFR gene of Plasmodium falciparum to pyrimethamine were cut with enzymes Bsrl Plamodium falciparum malaria in patients in the dr. Mohammad Hoesin Palembang hospital, Sek…