Background: Impetigo is a superficial skin infection in children mainly caused by Staphylococcus aureus. Although mupirocin is effective, long-term use may cause side effects and resistance. The pineapple core (Ananas comosus L. Merr.) contains bioactive compounds with potential antibacterial effects against S. aureus. This study aimed to evaluate the efficacy of pineapple core extract on the i…