Background. Multi Drug Resistant-TB (MDR-TB) is a condition where there is resistance to isoniazid (H) and rifampicin (R) simultaneously, with or without subsequent resistance to other first-line OAT. In 2021, WHO recorded around 450,000 MDR-TB cases in the world with a mortality rate of 191,000 cases. In Indonesia, there are about 28,000 cases of MDR-TB. This needs to receive great attention i…