Cempedak (Artocarpus champeden) leaves contain flavonoids that are efficacious as antioxidants which are thought to have potential as antidepressant activity. This study aims to determine the effect of cempedak leaf ethanol extract as an antidepressant and find out the best concentration of cempedak leaf ethanol extract as an antidepressant. Parameters observed included length of fall, immobili…