This study aims to determine the growth, nutritional content, and quality of organoleptic test of lettuce (Lactuca sativa L.) produced by biofortification of calcium (Ca) 300 ppm which is cultivated with a hydroponic system. The research was carried out at the Hydroponics House, Department of Agricultural Cultivation, Faculty of Agriculture, Sriwijaya University, Indralaya, Ogan Ilir, South Sum…