Introduction : Erythema nodosum leprosum (ENL) also known as type 2 leprosy reaction is a systemic acute inflammation reaction that is found in 30-50% of all leprosy patients. Leprosy patients with type 2 leprosy reaction is at risk of developing permanent damage or even disabilities. To this point, the diagnosis of ENL depends only on clinical observation and tends to be delayed. ENL is an acu…