The endophytic microorganism is a form of bacteria or a fungi microorganism that form colonies interiororgans of plants, but does not harm the host plant. The secondary metabolites compound heve been isolated from endophytic fungi (Penicillium citrinum) living in symbiotic dill for malaria that is brotowali ( Tinospora crispa L ). Isolation begin with cultivation of Penicillium citrinum fungi i…