Alkaloids have been isolated from the bark of tembesu (Fragraea fragrans Roxb). This study complements the report on the alkaloid content of the tembesu bark. The antibacterial activity test was carried out against Staphylococcus aureus and Pseudomonas aeruginosa bacteria. Tembesu bark was extracted by maceration using diethyl ether and fractionated with ethyl acetate, separation and purificati…