Acacia leaves (Acacia Mangium Wild) contain secondary metabolite compounds of flavonoids in the form of quercetin which have the potential as antidepressants. This study aims to determine the effect of giving ethanol extract of acacia leaves and its effective dose on antidepressant activity. This study used 30 test animals which were divided into 6 groups, namely, the normal group (1 NaCMC with…