Background: Porphyromonas gingivalis is one of the main etiologies in the pathogenesis of periodontal disease found in plaque. Plaque can be controlled using toothpaste. The combination of herbal ingredients and toothpaste can produce complementary effects. Meanwhile, Gambier extract (Uncaria gambir Roxb.) was reported to contain catechin and tannin which act as antibacterial. Objective: The pu…