The research of manufacturing and performance test membrane Cd and Zn Ion Selective Electrodes (ISE) with chitin ionophore, polyvinyl chloride (PVC) support matrix and dioctylphthalate (DOP) plasticizer or acetophenon has been done. The membrane Cd ISE and Zn were made by mixing 0.075 g of chitin, 0.25 g of lithium chloride (LiCl), 6 g of N, N-dimethyl acetamide (DMA), 6 g of 1-methyI-2-pyrroli…