Hypertension provides a major risk factor for cardiovascular and kidney disease. One of a therapy that used to treat a hypertension is diuretics. Gamal (Gliricidia sepium)contains flavonoid compounds which have diuretic effect. This study aims to determined activity of ethyl acetate fraction of gamal leaves as diuretic by measuring urine volume output and Na⁺, Cl⁻, dan K⁺ ion contents. Th…