Motile Aeromonas Septicemia (MAS) is common diseases occoured in freshwater fish. The disease is caused by the bacterium Aeromonas hydrophila. The mortality rate ranges caused by MAS infection in fish from 80-100% within 1-2 weeks (Kusen et al., 2015). Treatment of A. hydrophila infection be done by giving antibiotic, but it causes residues in the environment, fish and results in resistance to …