This study aims for developing an animation audiovisual media product in Excretory System material which is valid, practical, and effective at Grade XI High School. This study uses a 4D model which consists of Define, Design, Develop, and Dissemnate stages. Subjects of this study were 10 students of SMA Srijaya Negara which included 5 students of XI IPA 2 class and 5 students of XI IPA 3 class,…