Apigenin is the main flavonoid compound that has activity as a vasodilator that can increase hair growth. Flavonoid content in celery leaf extract was 49.83 mg/g with Rf value at TLC of 0.77. This study aims to determine the effect of variations in the concentration of sodium alginate of each formula of 1.6 mg; 3.2 mg and 4.8 mg on the resulting nanoparticles. The manufacture of nanoparticles w…