The formulation and characterization of glibenclamide into nanoparticles is a new delivery system for the use of glibenclamide drugs. The manufacture of SLN is carried out using high speed homogenization and ultrasonication methods. The solid lipid nanoparticles glibenclamide formula consisted of stearic acid as a lipid matrix, tween 80 as a surfactant, polietilena glikol 400 as a cosurfactant,…