Topical application is an act of giving anticaries material that in this study used APF gel 1.23% and NaF solution 2%. Fluoride as a topical application material has been reported to have an antibacterial effect that inhibits acid formation and growth of microorganisms in dental plaque. The purpose of this study was to compare the effectiveness of topical application with APF 1, 23% and NaF 2% …