Holothuria atra, Acanthaster planci, and Culcita novaeguineae as part of the Echinodermata phylum have the potential as a source of natural collagen that can be utilized in pharmacology. Collagen has potential bioactivities that act as antiaging, antioxidant, anti-inflammatory, and antimicrobial. This study aims to isolate and characterize collagen from the Echinodermata phylum in revealing the…