Background: Obesity is a global health problem that contributes to metabolic disorders, one of which is through changes in the structure and function of the pancreas, particularly the islets of Langerhans. Intermittent fasting, especially time- restricted feeding, is known to have the potential to improve metabolic parameters and tissue structure, but its effect on histology and islet diameter …
Background: Low birth weight (LBW) is a condition in which an infant is born weighing less than 2,500 grams, regardless of gestational age. LBW is an important indicator of perinatal health because it can lead to both short-term and long-term complications, such as growth impairment, increased risk of chronic diseases, and neonatal mortality. The occurrence of LBW is multifactorial, influenced …
Background: β-thalassemia major is a genetic disorder that causes chronic anemia, requiring patients to undergo regular lifelong blood transfusions. Repeated transfusions and ineffective erythropoiesis lead to iron accumulation, which is indicated by elevated serum ferritin levels. Iron overload can affect endocrine function, including growth hormone, thereby increasing the risk of growth diso…
Background. Pelvic organ prolapse (POP) is one of the most common pelvic floor disorders affecting women. This condition is caused by weakening of the pelvic floor supportive structures, with risk factors including age, obesity, menopause, parity, vaginal delivery, and a history of pelvic surgery. This study aims to determine the incidence of POP at RSUD Siti Fatimah Palembang and to identify t…
Introduction : Low back pain (LBP) is a global health problem that significantly impacts quality of life. LBP can be classified as inflammatory or non-inflammatory. Recently, the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been studied as practical, accessible, and economical inflammatory biomarkers, potentially supporting evaluation of inflammatory processe…
Background: Systolic blood pressure (SBP) is presumed to influence intraocular pressure (IOP), which is a major risk factor for glaucoma. However, previous studies have shown inconsistent findings. Furthermore, research directly assessing the relationship between SBP and primary angle-closure glaucoma (ACG) remains limited. Therefore, this study aimed to analyze the relationship between SBP and…
Low Back Pain is one of the most frequently encountered musculoskeletal complaints in healthcare settings and is associated with activity limitation, reduced productivity, and impaired quality of life. Inflammatory processes are believed to contribute to the pathophysiology of LBP, particularly in conditions related to autoimmune diseases, leading to the use of systemic inflammatory biomarkers …
Background: The increasing use of online games along with technological development may lead to Internet Gaming Disorder (IGD), a behavioral addiction recognized in DSM-5 and ICD-11. University students are a vulnerable group due to academic demands and greater autonomy in time management. Methods: This study was a descriptive observational study with a cross-sectional design involving 561 acti…
Background : Diabetes mellitus is a non-communicable disease with a high prevalence and is frequently accompanied by hypertension, which increases the risk of vascular complications and imposes a substantial burden on quality of life and healthcare costs. It is estimated that approximately 40–80% of patients with diabetes also have hypertension; therefore, identifying risk factors associated …
Critically ill children have complex nutritional needs and require intensive nutritional support to prevent organ dysfunction. This study evaluated differences in gastrointestinal tolerance to intermittent and bolus enteral nutrition rates in children on mechanical ventilation. A single-blind, randomized, controlled trial was conducted from May 2024 to March 2025 at Dr. Mohammad Hoesin Hospital…
Contributing Factors to Peripheral Nerve Conduction in Children with Type 1 Diabetes Background: (T1DM) in children results from autoimmune destruction of pancreatic β-cells, leading to absolute insulin deficiency and chronic hyperglycemia. This condition poses a risk for long-term complications, including diabetic peripheral neuropathy, which may affect sensory, motor, or autonomic nerves and…
ABSTRAK Uji Diagnostik Nilai Titik Potong Lingkar Lengan Atas untuk Mendeteksi Gangguan Gizi pada Bayi Usia 1 – < 6 Bulan Gangguan gizi dapat didiagnosis dengan pemeriksaan antropometri baik menggunakan berat badan dan panjang badan ataupun menggunakan lingkar lengan atas (LiLA). Lingkar lengan atas telah digunakan secara rutin untuk mendiagnosis gangguan gizi pada anak usia 6-59 bulan. Pada …
Anak dengan diabetes melitus tipe 1 (DMT1) memiliki risiko lebih tinggi mengalami gangguan perilaku akibat beban penyakit kronis yang dialaminya. Gangguan ini dapat memengaruhi perkembangan sosial, prestasi akademik, dan kualitas hidup secara keseluruhan. Penelitian ini bertujuan mengetahui prevalensi dan faktor risiko gangguan perilaku pada anak dengan DMT1. Penelitian observasional analitik d…
Background: Pelvic organ prolapse (POP) is a gynecological condition in which the pelvic organs descend from their normal anatomical position into the vagina due to weakness caused by decreased strength in the ligaments. This condition can lead to complications that affect daily life, one of which is a reduced quality of life. One of the management approaches for POP is a surgical procedure cal…
Background. Hyperuricemia is a condition characterized by increased uric acid levels due to excessive activity of the xanthine oxidase (XO) enzyme. Arcangelisia flava is known to contain secondary metabolites, such as flavonoids, alkanoids, and terpenoids, which have been reported to exhibit potential inhibitory effects on XO. This study aims to determine the effect of variations in ethanol sol…
ABSTRACT Factors Associated Constipation in Children with Cerebral Palsy at Mohammad Hoesin Hospital Background: Cerebral palsy (CP) is a neuromotor disorder often accompanied by constipation, which can impair quality of life and worsen clinical outcomes. Several factors such as functional independence level, communication ability, use of antiepileptic drugs (AEDs), CP type, and diet are suspec…
Emotional and behavioral disorders (EBD) are prevalent mental health issues among adolescents, particularly in those with obesity. Obesity affects not only physical health but also has potential psychosocial consequences. This study aimed to determine the prevalence of EBD among obese adolescents and analyze associated risk factors, including metabolic parameters and lifestyle. This was an obse…
Background: Oral mucositis is a common side effect of chemotherapy in children with cancer, which can reduce quality of life and interfere with treatment. Standard therapies such as chlorhexidine are not fully effective, prompting the need for a safe and effective adjunctive therapy. Randu honey is known to have anti-inflammatory, antibacterial, and tissue-healing properties. Objective: To eval…
Background: Cognitive impairment is characterized by a decline in the ability to think, remember, and perform daily activities, and its prevalence increases with age. Globally, more than 57 million people were living with dementia in 2021, and this number is projected to reach 139 million by 2050. In Indonesia, the number of individuals with dementia is estimated to increase to 4 million by 205…
Background: End-stage renal disease requires patients to undergo long-term hemodialysis, which may lead to psychological impacts, including stress. The duration of hemodialysis is suspected to be associated with stress levels, yet data regarding patients at Dr. Mohammad Hoesin General Hospital Palembang remain limited. This study aims to analyze the relationship between the duration of hemodial…
Background: Congenital heart disease (CHD) is a congenital abnormality that increases mortality and morbidity in early life. Infants with low birth weight (LBW) have a higher risk of developing CHD due to impaired organ maturation. Data on the association between LBW and CHD in Indonesia remain limited, particularly at dr. Mohammad Hoesin General Hospital. Methods: This study was an analytical …
Morbus Hansen (MH) is a chronic infectious disease caused by Mycobacterium leprae, which affects the skin and peripheral nerves and remains a significant public health concern in Indonesia. According to the WHO classification, MH is divided into paucibacillary (PB) and multibacillary (MB) types. Laboratory examinations, including slit-skin smear (SSS), bacterial index (BI), morphological index …
Kidney and urinary tract diseases in children can cause complications such as acute and chronic kidney disease. Proteinuria is an important marker for early detection. Dipstick urinalysis, manual or automated, is widely used for its speed and simplicity, though accuracy may differ. No study has compared these methods at Kemenkes RS Dr. Mohammad Hoesin Palembang. This descriptive comparative stu…
Stroke is a leading cause of death and disability worldwide and represents one of the non-communicable diseases with the highest burden in Indonesia. Healthcare workers at the primary care level play a crucial role in early detection, education, and initial management of stroke. Previous studies have demonstrated variability in healthcare workers’ levels of knowledge, attitudes, and practices…
Background: Gout is a chronic condition caused by the accumulation of monosodium urate (MSU) crystals due to hyperuricemia, often associated with a diet high in purines, obesity, and other metabolic disorders. Allopurinol is the first-line drug used to lower serum uric acid levels in gout patients. Ensuring the correct dosage of allopurinol is essential to enhance therapeutic effectiveness and …
Background: Tuberculosis (TB) is an infectious disease that remains a major public health concern. The physical environment within the home, particularly indoor air quality, is suspected to contribute to the increased risk of TB transmission. This study aimed to determine the relationship between indoor air quality and the incidence of TB in the working area of Puskesmas Sukarami. Methods: This…
Background: Packaged drinking water (AMDK) is widely consumed due to its convenience and perceived hygiene; however, its chemical quality does not always meet established standards. Components such as pH and heavy metals exceeding permissible limits can pose health risks. Therefore, an analysis of AMDK chemical quality based on the Environmental Quality Standard (SBMKL) PMK No. 2 of 2023 is nec…
Background: Arcangelisia flava, commonly known as yellow wood, is an Indonesian medicinal plant containing bioactive compounds such as phenols and flavonoids, which act as natural antioxidants. The antioxidant activity of plant extracts is strongly influenced by the type and concentration of solvent used during extraction. Therefore, selecting the optimal solvent concentration is essential to o…
Background: Essential fatty acids omega-3 and omega-6 play an important role during pregnancy, particularly in supporting fetal neurological development and immune system maturation. An imbalance in the omega-3/omega-6 ratio has been associated with an increased risk of pregnancy complications, while previous studies have reported low essential fatty acid intake among pregnant women in Indonesi…
Background: Bladder cancer is a prevalent urological malignancy strongly linked to exposure to tobacco-derived carcinogens, yet the influence of smoking behavior on its clinical and histopathological characteristics remains inconsistent across populations. Objective: This study aimed to assess the association between smoking status and both histopathological grading and clinical staging among p…