Background: Parkinson's disease is a progressive neurodegenerative disorder characterized by the degeneration of dopaminergic neurons in the substantia nigra. Long-term L-Dopa therapy is associated with the development of motor complications that reduce patients' quality of life. Safinamide is a selective reversible MAO-B inhibitor with an additional mechanism of glutamate release modulation, d…
Background: Diabetes mellitus (DM) is a global health burden with a continuously rising prevalence. Indonesia ranks seventh among countries with the highest number of people living with diabetes, with an estimated 10.7 million patients in 2019. Poor sleep quality is one of the most prevalent comorbidities in patients with DM and has been shown to impair glycemic control. Despite growing evidenc…
ABSTRACT ACCURACY OF HBA1C, HYPERTENSION, AND LDL AS PREDICTORS OF DIABETIC RETINOPATHY SEVERITY Oliffa Salma, AK Anyori, Ramzi Amin, Yulianto Kusnadi, Erial Bahar Department of Ophthalmology, Faculty of Medicine, Sriwijaya University, Mohammad Hoesin General Hospital, Palembang, Indonesia Background: Diabetic retinopathy (DR) is a leading microvascular complication of diabetes mellitus and a m…
Severe acute malnutrition (SAM) remains a global health challenge; Indonesia's wasting rate reached 8.5% in 2023, surpassing the national target of 7%. Children with SAM experience depleted visceral protein stores, including prealbumin, and heightened systemic inflammation reflected by elevated high-sensitivity C-reactive protein (hs-CRP), each condition mutually exacerbating the other. Snakehe…