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UJI ANTINEFROLITHIASIS FRAKSI ETANOL DAUN MELINJO (Gnetum gnemon L.) TERHADAP…
Melinjo leaves (Gnetum gnemon L) is one plant that has many properties, one of which is as a diuretic. Active compounds such as alkaloids, flavonoids, steroids, and tannins can be found in melinjo. Antinephrolithiasis testing of ethanol fraction of melinjo leaves was carried out in vivo with the aim of determining the effect on ureal levels, creatinine and calcium, crystalluria and urine pH, as…
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- xviii, 137 hlm.; ilus.; tab.; 29 cm.
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- T1453502024
UJI EFEK ANTIDIABETES FRAKSI N-HEKSAN KULIT BUAH PISANG (Musa balbisiana C.) …
Kulit buah pisang kepok (Musa balbisian C.) diketahui mengandung metabolit sekunder flavonoid yang memiliki efek antidiabetes. Tujuan dilakukan penelitan ini untuk mengetahui efektivitas penurunan kadar glukosa darah fraksi n-heksan kulit buah pisang . Penelitian ini dibagi menjadi 6 kelompok yaitu kelompok normal (suspense Na-CMC 0,5%), kontrol positif (metformin 9mg/kgBB), kontrol negatif (su…
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- vii, 90 hlm.; tab.; illus.; 29 cm
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- T1458792024
UJI KADAR FLAVONOID TOTAL DAN AKTIVITAS ANTIOKSDIAN SECARA IN VITRO PADA FRAK…
Free radical can trigger chain reactions that cause damage to cell-forming particles that can have an impact on health. One of the plants that has the potential as a source of antioxidants is purple sweet potato leaves (Ipomoea batatas L. Poir) which contains a secondary metalbolite component with antioxidant effectiveness relatively higher than tocopherol. This study aims to determine the Anti…
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- xiv, 41 hlm.; ilus.; tab.; 29 cm.
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- T1446462024
PREPARASI DAN UJI AKTIVITAS ANTIDIABETES NANOSUSPENSI EKSTRAK DAUN MELINJO (G…
Melinjo leaves has pharmacological activity as an antidiabetic because it contains flavonoid compounds which can inhibit glucose absorption, stimulate insulin secretion or act as insulin and can regulate the work of enzymes that play a role in carbohydrate metabolism. The effectiveness and bioavailability of extracts tend to be low so that the formula in the form of nanosuspension is an option …
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- xviii, 105 hlm.; ilus.; tab.; 29 cm.
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- T1451092024
PREPARASI DAN UJI AKTIVITAS ANTIDIABETES NANOSUSPENSI EKSTRAK DAUN MELINJO (G…
Melinjo leaves are known to have pharmacological activity as antidiabetics because they contain flavonoid compounds that can reduce blood glucose levels with their ability to act as antioxidants that protect β-cell damage as insulin producers and can increase insulin sensitivity. The effectiveness, bioavailability, and solubility of extracts tend to be low, so the formula in the form of nanosu…
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- xix, 101 hlm.; ilus.; tab.; 29 cm.
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- T1449962024
UJI AKTIVITAS ANTIDEPRESAN EKSTRAK ETANOL DAUN CEMPEDAK (Artocarpus champeden…
Cempedak (Artocarpus champeden) leaves contain flavonoids that are efficacious as antioxidants which are thought to have potential as antidepressant activity. This study aims to determine the effect of cempedak leaf ethanol extract as an antidepressant and find out the best concentration of cempedak leaf ethanol extract as an antidepressant. Parameters observed included length of fall, immobili…
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- xvii, 99 hlm.; ilus.; tab.; 28cm
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- T1440172024
UJI TOKSISITAS AKUT EKSTRAK ETANOL DAUN KENCANA UNGU (Ruellia tuberosa L.) TE…
Daun kencana ungu (Ruellia tuberosa L.) mengandung senyawa metabolit sekunder seperti flavonoid, alkaloid, tannin, saponin dan steroid yang memiliki efek terapi sebagai antidiabetes dan diuretik. Senyawa yang terkandung bermanfaat sebagai obat perlu diketahui keamanannya yang didukung dengan pengujian toksisitas. Tujuan penelitian ini untuk mengetahui hasil ekstraksi dan skrining fitokimia, dos…
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- xx, 74 hlm.; ilus.; 29 cm.
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- T1416212024
AKTIVITAS ANTIBAKTERI NANOEMULSI DAUN SAMBILOTO DENGAN KOMBINASI TWEEN 80 DAN…
Bitter leaf extract (Andrographis paniculate (Burm.f) Wall. Ex Ness) contains secondary metabolites andrographolide and quercetin which have potential antibacterial activity. This research aims to determine the nanoemulsion formulation with a combination of Tween 80 and Ethanol 96% concentration on the activity of Propionibacterium acnes and the stability of ICH Q1A (R2). Data analysis in this …
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- xviii, 73 hlm.; ilus.; tab.; 29 cm.
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- T1386572023
UJI AKTIVITAS NANOFIBER KOMBINASI EKSTRAK DAUN SIRIH (Piper betle) DAN DAUN B…
Open wounds are very susceptible to infection, can become ulcers and even chronic if they are not treated and cared for properly. Nanofiber as a modern wound dressing can deliver medicinal ingredients for caring wound. Betel leaves (Piper betle) and Binahong leaves (Anredera cordifolia) contain flavonoids, saponins, tannins which can accelerate the wound healing process. The aim of this study i…
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- xvii, 80 hlm.; ilus.; tab.; 29 cm.
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- T1296232023
ANALISIS HUBUNGAN TINGKAT KEPATUHAN MINUM OBAT ANTITUBERKULOSIS TERHADAP KUAL…
Pulmonary tuberculosis treatment for a long time at least 6 months with side effects making it a challenge for patients to complete treatment. Cases of low adherence to taking medication are still found in pulmonary TB patients. This study aim to analyze the relationship between medication adherence and the quality of life of pulmonary TB patients. Analytical observational research design with …
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- xvii, 80 hlm.; tab.; 29 cm.
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- T1390112024
STUDI SISTEM DISPERSI PADAT ASAM MEFENAMAT DENGAN KOMBINASI KITOSAN DAN NA-AL…
Mefenamic acid is a drug included in the biopharmaceutical classification system (BCS) class II so it is difficult to dissolve water which is overcome by making it into a solid dispersion. The combination of chitosan and sodium alginate is used as a carrier substance in solid dispersion. This study aims to determine the effect of chitosan and sodium alginate as a carrier on the dissolution rate…
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- xix, 80 hlm.; ilus.; tab.; 29 cm.
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- T1388652024
AKTIVITAS ANTIBAKTERI NANOEMULSI DAUN SAMBILOTO DENGAN KOMBINASI TWEEN 20 DAN…
Sambiloto leaves (Andrographis paniculate (Burm. F) Wall ex. Ness) contain andrografolid and flavonoids as the main compounds that have potential as antibacterial. Nanoemulsion with a combination of tween 20 and PEG-400 was carried out to produce preparations that have better antibacterial effects and are thermodynamically stable. This study was conducted to determine the characteristics and st…
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- xi, 71 hlm.; ilus.; 29 cm.
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- T1386562024
STUDI IN SILICO POTENSI SENYAWA DAUN OREGANO (Origanum vulgare L.) SEBAGAI AG…
Tuberculosis is a contagious respiratory tract infection caused by Mycobacterium tuberculosis. This research utilized an in silico approach to predict the molecular potential of target compounds in oregano leaves (Origanum vulgare L.) for antituberculosis activity. The potential compounds in oregano leaves included phytol, carvacrol, γ-terpinene, p-cymene, and cyclotetradecane. The SwissADME d…
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- xviii, 161 hlm.; ilus.; 29 cm.
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- T1388672024
OPTIMASI FORMULA NANOENKAPSULASI MODIFIKASI POLIMER KITOSAN-ALGINAT PEMBAWA F…
Spirulina platensis is a blue-green algae species that contains phycocyanin. The low stability of phycocyanin requires an effective delivery system, one of which is through the process of nanoencapsulation using the ionic gelation method. Potential natural polymers serving as encapsulating agents include chitosan and alginate. Folic acid is among the targeting moieties used for the targeted del…
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- xx, 105 hlm.; ilus.; 29 cm.
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- T1391792024
PENENTUAN INDEKS PREBIOTIK TEPUNG MAGGOT BSF TERHADAP BIFIDOBACTERIUM BIFIDUM…
BSF maggot flour has the highest protein content as well as other ingredients such as carbohydrates, fatty acids, minerals, antimicrobial peptide (AMP), and chitin. BSF maggot flour protein can be utilized by Bifidobacterium bifidum (B. bifidum) to stimulate its growth. The purpose of this study was to determine the potential of BSF maggot flour as a prebiotik by testing its effect, index, and …
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- xviii, 76 hlm.; ilus.; 29 cm.
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- T1423052024
OPTIMASI KONSENTRASI TWEEN 80 DAN ETANOL 96% DALAM SEDIAAN NANOEMULSI EKSTRAK…
Ekstrak daun sukun (Artocarpus altilis (Parkinson) Fosberg) mengandung senyawa metabolit sekunder utama flavonoid dan fenolik. Penelitian ini bertujuan untuk mengetahui optimum konsentrasi Tween 80 dan Etanol 96% dalam sediaan nanoemulsi ekstrak etanol daun sukun. Optimasi dilakukan dengan desain faktorial 22 menggunakan Design Expert 12®. Formula optimum yang diperoleh selanjutnya dilakukan k…
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- xviii, 98 hlm.; ilus.; 29 cm.
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- T1423532024
PEMBERIAN SELF-NANO EMULSION EKSTRAK BIJI PEPAYA (Carica papaya) TERHADAP KUA…
Carica papaya is known to reduce the quality of spermatozoa in rats. Papaya seed formulation in the form of SNE (Self-Nano Emulsion) is an alternative drug delivery system to increase bioavailability by lipophilic means. Papaya seed extract was characterized using GC-MS to see the compounds contained therein. Papaya seed extract was formulated into Self-nano emulsion and evaluated including pH,…
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- xviii, 70 hlm.; tab.; 29 cm.
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- T1425052024
ANALISIS HUBUNGAN KEPATUHAN MINUM OBAT ANTIHIPERTENSI TERHADAP KUALITAS HIDUP…
Penyakit hipertensi merupakan salah satu penyebab utama kematian di dunia dengan peningkatan prevalensi seiring bertambahnya usia pada pasien geriatri (usia ≥ 60 tahun). Proses degeneratif dan banyaknya jumlah obat yang harus diminum dapat menimbulkan masalah kepatuhan minum obat yang dapat mempengaruhi kualitas hidup pasien geriatri hipertensi. Penelitian ini bertujuan untuk menganalisis hub…
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- xviii, 96 hlm.; tab.; 29 cm.
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- T1421152024
KAJIAN DRUG RELATED PROBLEMS (DRPs) PADA PASIEN GAGAL GINJAL KRONIK DENGAN AT…
Chronic renal failure is a condition in which kidney function decreases progressively and can cause various complications that can increase the potential for Drug Related Problems (DRPs). The purpose of this study was to determine the incidence of Drug Related Problems (DRPs) and the percentage of incidence of DRPs in patients with chronic renal failure with or without complications at RSUD Sit…
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- xix, 66 hlm.; ilus.; tab.; 29 cm.
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- T1419422024
STUDI STABILITAS PROTRANSETOSOM KLINDAMISIN HCL DENGAN LIOPROTEKTAN TREHALOSA…
Clindamycin HCl as a topical anti-acne drug has low bioavailability due to its hydrophilic nature which is difficult to penetrate the stratum corneum. Propionibacterium acnes, the main pathogen of acne, lives in the sebaceous glands in the dermis, so it requires deeper penetration. Transethosomes can increase penetration because they are classified as lipid nanovesicles with good elasticity and…
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- xvii, 99 hlm.; ilus.; 29 cm.
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- T1389142024
OPTIMASI PATCH TRANSDERMAL EKSTRAK KULIT MANGGIS (Garcinia mangostana L.) TER…
Wounds or damage to part of the body tissue if not treated immediately will cause infection and even death. Plants that can help the wound healing process include alpha mangostin compounds from mangosteen skin (Garcinia mangostana L.). Optimization of active substance delivery is carried out in the form of transdermal patch preparations. This study aims to obtain the optimum formula for transde…
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- xix, 92 hlm.; ilus.; 29 cm.
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- T1401532024
PENENTUAN INDEKS PREBIOTIK TEPUNG MAGGOT BSF TERHADAP Lactobacillus plantarum…
BSF (Black Soldier Fly) maggot flour has a high protein content that can act as a natural prebiotic. Lactic Acid Bacteria (LAB) of the genus Lactobacillus such as Lactobacillus plantarum (L. plantarum) produce bacteriocins that can inhibit the growth of pathogenic bacteria such as Escherichia coli (E. coli). This study aims to see the effect and prebiotic index of BSF maggot flour in inhibiting…
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- xviii, 75 hlm.; ilus.; 29 cm.
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- T1424552024
EVALUASI PENGGUNAAN OBAT PADA PASIEN DISPEPSIA RAWAT JALAN DI RSUD SITI FATIM…
Dyspepsia is a condition of discomfort that persists (episodic) or experiences recurrence of pain in the upper abdomen, nausea, vomiting, bloating, fullness, fullness of the stomach, and pain in the epigastrium. with an incidence proportion of 35.5% in Palembang City in 2015. Rational use of dyspepsia medication is very important to ensure that the medication given is appropriate, safe, and eff…
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- xxiii, 57 hlm.; ilus.; tab.; 29 cm.
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- T1454552024
PREPARASI DAN KARAKTERISASI TRANSDERMAL PATCH EKSTRAK KULIT MANGGIS (Garcinia…
Mangosteen peel extract has an alfa-mangosteen compound that can accelerate cell healing by stimulating fibroblast growth, thus providing effects as an anti�inflammatory and antimicrobial. The choice of transdermal patch dosage form for mangosteen peel extract aims to effectively deliver active substances through the skin to reach the systemic. The purpose of this study was to obtain a formul…
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- xviii, 64 hlm.; ilus.; 29 cm.
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- T1399032024
OPTIMASI DAN UJI AKTIVITAS ANTIBAKTERI ETOSOM FRAKSI ETIL ASETAT EKSTRAK DAUN…
Daun singkong (Manihot Esculenta Crantz.) mengandung senyawa metabolit yang dihasilkan salah satunya flavonoid terdapat rutin dikenal sebagai quercetin-3-rutinoside yang berpotensi sebagai anti acne. Etosom memiliki kemampuan sebagai pengantar untuk meningkatkan transfer bahan aktif melalui kulit dengan lebih efisien dalam hal permeabilitas kulit. Tujuan dari penelitian ini adalah mengetahui fo…
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- xx, 137 hlm.; ilus.; tab.; 29 cm.
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- T1401952024
UJI AKTIVITAS HEPATOPROTEKTOR EKSTRAK ETANOL DAUN KENCANA UNGU (Ruellia Tuber…
The Purple golden leaves (Ruellia tuberosa L.) contain secondary metabolites in the form of flavonoid compounds which have antioxidant activity which can act as a hepatoprotector. This study aims to determine the hepatoprotective activity of ethanol extract of purple golden leaves (Ruellia tuberosa L.) in male Wistar white rats induced by CCl4 based on parameters measuring SGOT, SGPT and ALP le…
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- xix, 64 hlm.; ilus.; 29 cm.
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- T1454332024
UJI AKTIVITAS DIURETIK EKSTRAK ETANOL DAUN KENCANA UNGU (Ruellia tuberosa L.)…
The leaves of the kencana ungu (Ruellia tuberosa L.) contains flavonoid compounds potentially as diuretics. This study aims to determine the diuretic activity of ethanol extract of kencana ungu leaves. Diuretic activity testing was carried out on 6 groups of test animals including normal (aquades), negative (NaCMC), positive (Furosemide), and three groups of treatment doses of 100, 200 and 400 …
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- xix, 76 hlm.; ilus.; 29 cm.
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- T1424152024
PENENTUAN INDEKS PREBIOTIK TEPUNG MAGGOT BSF TERHADAP Lactobacillus bulgaricu…
BSF maggots are the larvae of the fly Hermetia illucens L. BSF maggot flour has a very high animal protein content, besides that BSF maggot flour also contains carbohydrates, amino acids, chitin and Antimircobial peptide (AMP). This research aims to determine the effect, index and activity values that can determine the potential of BSF maggot flour as a prebiotic agent using L. bulgaricus Lacti…
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- xix, 81 hlm.; ilus.; 29 cm.
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- T1424842024
AKTIVITAS ANTIBAKTERI KOMBINASI TEPUNG MAGGOT BSF DAN TEPUNG IKAN GABUS TERHA…
Tepung maggot BSF (TMB) dan tepung ikan gabus (TIG) memiliki Antimicrobial peptide dan senyawa lain sebagai antibakteri yang bersifat bakterisidal. Penelitian ini dilakukan untuk mengetahui aktivitas antibakteri kombinasi TMB dan TIG terhadap Escherichia coli dan Staphylococcus aureus. Uji aktivitas antibakteri dilakukan dengan mencari Konsentrasi Hambat Minimum (KHM) TMB dan TIG tunggal, Konse…
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- xxi, 144 hlm.; ilus.; 29 cm.
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- T1423012024
AKTIVITAS ANTIBAKTERI KOMBINASI MINYAK LARVA BSF DAN MINYAK IKAN TUNA TERHADA…
Staphylococcus aureus bacterial infection is a health threat. Treatment of infections using antibiotics has been widely used. However, misuse of antibiotics can cause resistance. One way to overcome typically by creating common fixings as antibacterials. BSF larvae oil (MLB) and tuna fish oil (MIT) are known to have antibacterial potential. This study aims to determine the antibacterial activit…
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- xvii, 137 hlm.; ilus.; tab.; 29 cm.
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- T1423772024
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