AKTIVITAS ANTIBAKTERI NANOEMULSI DAUN SAMBILOTO DENGAN KOMBINASI TWEEN 20 DAN…

Sambiloto leaves (Andrographis paniculate (Burm. F) Wall ex. Ness) contain andrografolid and flavonoids as the main compounds that have potential as antibacterial. Nanoemulsion with a combination of tween 20 and PEG-400 was carried out to produce preparations that have better antibacterial effects and are thermodynamically stable. This study was conducted to determine the characteristics and st…

STUDI IN SILICO POTENSI SENYAWA DAUN OREGANO (Origanum vulgare L.) SEBAGAI AG…

Tuberculosis is a contagious respiratory tract infection caused by Mycobacterium tuberculosis. This research utilized an in silico approach to predict the molecular potential of target compounds in oregano leaves (Origanum vulgare L.) for antituberculosis activity. The potential compounds in oregano leaves included phytol, carvacrol, γ-terpinene, p-cymene, and cyclotetradecane. The SwissADME d…

OPTIMASI FORMULA NANOENKAPSULASI MODIFIKASI POLIMER KITOSAN-ALGINAT PEMBAWA F…

Spirulina platensis is a blue-green algae species that contains phycocyanin. The low stability of phycocyanin requires an effective delivery system, one of which is through the process of nanoencapsulation using the ionic gelation method. Potential natural polymers serving as encapsulating agents include chitosan and alginate. Folic acid is among the targeting moieties used for the targeted del…

PENENTUAN INDEKS PREBIOTIK TEPUNG MAGGOT BSF TERHADAP BIFIDOBACTERIUM BIFIDUM…

BSF maggot flour has the highest protein content as well as other ingredients such as carbohydrates, fatty acids, minerals, antimicrobial peptide (AMP), and chitin. BSF maggot flour protein can be utilized by Bifidobacterium bifidum (B. bifidum) to stimulate its growth. The purpose of this study was to determine the potential of BSF maggot flour as a prebiotik by testing its effect, index, and …

OPTIMASI KONSENTRASI TWEEN 80 DAN ETANOL 96% DALAM SEDIAAN NANOEMULSI EKSTRAK…

Ekstrak daun sukun (Artocarpus altilis (Parkinson) Fosberg) mengandung senyawa metabolit sekunder utama flavonoid dan fenolik. Penelitian ini bertujuan untuk mengetahui optimum konsentrasi Tween 80 dan Etanol 96% dalam sediaan nanoemulsi ekstrak etanol daun sukun. Optimasi dilakukan dengan desain faktorial 22 menggunakan Design Expert 12®. Formula optimum yang diperoleh selanjutnya dilakukan k…

PEMBERIAN SELF-NANO EMULSION EKSTRAK BIJI PEPAYA (Carica papaya) TERHADAP KUA…

Carica papaya is known to reduce the quality of spermatozoa in rats. Papaya seed formulation in the form of SNE (Self-Nano Emulsion) is an alternative drug delivery system to increase bioavailability by lipophilic means. Papaya seed extract was characterized using GC-MS to see the compounds contained therein. Papaya seed extract was formulated into Self-nano emulsion and evaluated including pH,…

ANALISIS HUBUNGAN KEPATUHAN MINUM OBAT ANTIHIPERTENSI TERHADAP KUALITAS HIDUP…

Penyakit hipertensi merupakan salah satu penyebab utama kematian di dunia dengan peningkatan prevalensi seiring bertambahnya usia pada pasien geriatri (usia ≥ 60 tahun). Proses degeneratif dan banyaknya jumlah obat yang harus diminum dapat menimbulkan masalah kepatuhan minum obat yang dapat mempengaruhi kualitas hidup pasien geriatri hipertensi. Penelitian ini bertujuan untuk menganalisis hub…

KAJIAN DRUG RELATED PROBLEMS (DRPs) PADA PASIEN GAGAL GINJAL KRONIK DENGAN AT…

Chronic renal failure is a condition in which kidney function decreases progressively and can cause various complications that can increase the potential for Drug Related Problems (DRPs). The purpose of this study was to determine the incidence of Drug Related Problems (DRPs) and the percentage of incidence of DRPs in patients with chronic renal failure with or without complications at RSUD Sit…

STUDI STABILITAS PROTRANSETOSOM KLINDAMISIN HCL DENGAN LIOPROTEKTAN TREHALOSA…

Clindamycin HCl as a topical anti-acne drug has low bioavailability due to its hydrophilic nature which is difficult to penetrate the stratum corneum. Propionibacterium acnes, the main pathogen of acne, lives in the sebaceous glands in the dermis, so it requires deeper penetration. Transethosomes can increase penetration because they are classified as lipid nanovesicles with good elasticity and…

OPTIMASI PATCH TRANSDERMAL EKSTRAK KULIT MANGGIS (Garcinia mangostana L.) TER…

Wounds or damage to part of the body tissue if not treated immediately will cause infection and even death. Plants that can help the wound healing process include alpha mangostin compounds from mangosteen skin (Garcinia mangostana L.). Optimization of active substance delivery is carried out in the form of transdermal patch preparations. This study aims to obtain the optimum formula for transde…

PENENTUAN INDEKS PREBIOTIK TEPUNG MAGGOT BSF TERHADAP Lactobacillus plantarum…

BSF (Black Soldier Fly) maggot flour has a high protein content that can act as a natural prebiotic. Lactic Acid Bacteria (LAB) of the genus Lactobacillus such as Lactobacillus plantarum (L. plantarum) produce bacteriocins that can inhibit the growth of pathogenic bacteria such as Escherichia coli (E. coli). This study aims to see the effect and prebiotic index of BSF maggot flour in inhibiting…

EVALUASI PENGGUNAAN OBAT PADA PASIEN DISPEPSIA RAWAT JALAN DI RSUD SITI FATIM…

Dyspepsia is a condition of discomfort that persists (episodic) or experiences recurrence of pain in the upper abdomen, nausea, vomiting, bloating, fullness, fullness of the stomach, and pain in the epigastrium. with an incidence proportion of 35.5% in Palembang City in 2015. Rational use of dyspepsia medication is very important to ensure that the medication given is appropriate, safe, and eff…

PREPARASI DAN KARAKTERISASI TRANSDERMAL PATCH EKSTRAK KULIT MANGGIS (Garcinia…

Mangosteen peel extract has an alfa-mangosteen compound that can accelerate cell healing by stimulating fibroblast growth, thus providing effects as an anti�inflammatory and antimicrobial. The choice of transdermal patch dosage form for mangosteen peel extract aims to effectively deliver active substances through the skin to reach the systemic. The purpose of this study was to obtain a formul…

OPTIMASI DAN UJI AKTIVITAS ANTIBAKTERI ETOSOM FRAKSI ETIL ASETAT EKSTRAK DAUN…

Daun singkong (Manihot Esculenta Crantz.) mengandung senyawa metabolit yang dihasilkan salah satunya flavonoid terdapat rutin dikenal sebagai quercetin-3-rutinoside yang berpotensi sebagai anti acne. Etosom memiliki kemampuan sebagai pengantar untuk meningkatkan transfer bahan aktif melalui kulit dengan lebih efisien dalam hal permeabilitas kulit. Tujuan dari penelitian ini adalah mengetahui fo…

UJI AKTIVITAS HEPATOPROTEKTOR EKSTRAK ETANOL DAUN KENCANA UNGU (Ruellia Tuber…

The Purple golden leaves (Ruellia tuberosa L.) contain secondary metabolites in the form of flavonoid compounds which have antioxidant activity which can act as a hepatoprotector. This study aims to determine the hepatoprotective activity of ethanol extract of purple golden leaves (Ruellia tuberosa L.) in male Wistar white rats induced by CCl4 based on parameters measuring SGOT, SGPT and ALP le…

UJI AKTIVITAS DIURETIK EKSTRAK ETANOL DAUN KENCANA UNGU (Ruellia tuberosa L.)…

The leaves of the kencana ungu (Ruellia tuberosa L.) contains flavonoid compounds potentially as diuretics. This study aims to determine the diuretic activity of ethanol extract of kencana ungu leaves. Diuretic activity testing was carried out on 6 groups of test animals including normal (aquades), negative (NaCMC), positive (Furosemide), and three groups of treatment doses of 100, 200 and 400 …

PENENTUAN INDEKS PREBIOTIK TEPUNG MAGGOT BSF TERHADAP Lactobacillus bulgaricu…

BSF maggots are the larvae of the fly Hermetia illucens L. BSF maggot flour has a very high animal protein content, besides that BSF maggot flour also contains carbohydrates, amino acids, chitin and Antimircobial peptide (AMP). This research aims to determine the effect, index and activity values that can determine the potential of BSF maggot flour as a prebiotic agent using L. bulgaricus Lacti…

AKTIVITAS ANTIBAKTERI KOMBINASI TEPUNG MAGGOT BSF DAN TEPUNG IKAN GABUS TERHA…

Tepung maggot BSF (TMB) dan tepung ikan gabus (TIG) memiliki Antimicrobial peptide dan senyawa lain sebagai antibakteri yang bersifat bakterisidal. Penelitian ini dilakukan untuk mengetahui aktivitas antibakteri kombinasi TMB dan TIG terhadap Escherichia coli dan Staphylococcus aureus. Uji aktivitas antibakteri dilakukan dengan mencari Konsentrasi Hambat Minimum (KHM) TMB dan TIG tunggal, Konse…

AKTIVITAS ANTIBAKTERI KOMBINASI MINYAK LARVA BSF DAN MINYAK IKAN TUNA TERHADA…

Staphylococcus aureus bacterial infection is a health threat. Treatment of infections using antibiotics has been widely used. However, misuse of antibiotics can cause resistance. One way to overcome typically by creating common fixings as antibacterials. BSF larvae oil (MLB) and tuna fish oil (MIT) are known to have antibacterial potential. This study aims to determine the antibacterial activit…

FORMULASI DAN UJI ANTIBAKTERI SEDIAAN PATCH TRANSDERMAL FRAKSI ETIL ASETAT DA…

Cassava leaves contain rutin compounds which are flavonoid derivatives that have antibacterial properties. Transdermal patch preparation was chosen for the ethyl acetate fraction of cassava leaves because it can produce effective preparations to deliver active compounds through the skin to reach the systemic. This study aims to obtain the best formula with plasticizer concentration in transderm…

FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI TRANSDERMAL PATCH FRAKSI ETIL ASETAT …

Fraksi etil asetat daun singkong mengandung senyawa rutin yang efektif menghambat pertumbuhan bakteri Staphylococcus aureus. Penelitian ini bertujuan mengetahui variasi konsentrasi kalsium klorida sebagai crosslinker terhadap transdermal patch yang dihasilkan dan mengetahui aktivitas antibakteri sediaan transdermal patch. Polimer yang digunakan pada penelitian ini adalah kitosan dan natrium alg…

STUDI STABILITAS PROTRANSETOSOM KLINDAMISIN HCL DENGAN LIOPROTEKTAN SUKROSA M…

Clindamycin HCl has hydrophilic properties so if made in conventional topical formulations it has problems penetrating into the dermis layer. Transethosomes as a drug delivery system can be used in the transdermal route to increase the permeation of active substances. However, transethosomes in suspension form are still a challenge in terms of storage and stability. This study aims to overcome …

UJI IN VITRO ANTIOKSIDAN DAN UJI IN VIVO ANTIINFLAMASI FRAKSI DAUN NANGKA (Ar…

Jackfruit (Artocarpus heterophyllus) is a medicinal plant that is rich in phenolic and flavonoid compounds. Phenolic compounds are known to have high potential as antioxidants. Compounds that act as antioxidants generally also have the potential to act as anti-inflammatory. This study aims to determine the in vitro antioxidant activity and in vivo anti-inflammatory activity of A. heterophyllus …

STUDI STABILITAS PROTRANSETOSOM KLINDAMISIN HCL DENGAN LIOPROTEKTAN MANITOL M…

The topical anti-acne preparation clindamycin HCl has low bioavailability (5-8%) because its hydrophilic makes it difficult to penetrate the stratum corneum where Propionibacterium acnes resides. Efforts have been made to increase the bioavailability of clindamycin HCl through development into transethosomes, but clindamycin HCl transethosomes have less than optimal stability (shelf life

POTENSI EKSTRAK ETANOL DAN FRAKSI DAUN PELAWAN (Tristaniopsis merguensis Grif…

Free radicals trigger oxidative stress through an increase in Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) which leads to degenerative diseases such as cancer, cardiovascular diseases, and others. Antioxidants are needed to protect from free radicals. One of the plants that has potential as a natural antioxidant is pelawan leaves (Tristaniopsis merguensis Griff). Secondary …

STUDI MOLEKULER POTENSI SENYAWA PADA DAUN Clinacanthus nutans SEBAGAI ANTIPRO…

Kanker payudara adalah kelainan pada payudara yang berupa tumor karena proliferasi sel. Penelitian ini bertujuan memprediksi potensi molekuler dari senyawa daun Clinacanthus nutans terhadap aktivitas antiproliferasi kanker payudara dengan pendekatan bioinformatika. Ekstrak yang memiliki senyawa potensi ditelaah interaksi molekulernya. Basis data pkCSM menampilkan profil ADMET tiap senyawa. Basi…

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAN FRAKSI DAUN SEBURO (GARCINIA FOR…

Reactive radicals cause oxidative stress, leading to cell damage. Antioxidants can convert radicals into less reactive ones. Seburo leaf (Garcinia forbesii King) has the potential as a natural antioxidant containing flavonoids, phenolic compounds, saponins, tannins, triterpenoids and steroids. This study aims to determine the characteristics of ethanol extracts, the effect of giving ethanol ext…

FARMASI KLINIS OXFORD (Oxford Handbook of Clinical Pharmacy)

Edition

-

ISBN/ISSN

978-979-044-493-5

Collation

xxviii, 627 hlm.; 21 cm.; illus.

Series Title

-

Call Number

615.4 Far f

Glosarium Farmasi

Edition

1

ISBN/ISSN

979-461-405-X

Collation

vii, 229 hlm.; 21 cm.

Series Title

-

Call Number

615.1 Glo g

Stabilitas Kimiawi Sediaan Farmasi : BUKU PEGANGAN BAGI TENAGA FARMASI, EDIS…

Edition

2

ISBN/ISSN

979-8107-46-2

Collation

xiii, 388 hlm.; 23 cm.; Illus.

Series Title

-

Call Number

615.18 Con s