Latar belakang: Aggregatibacter actinomycetemcomitans adalah bakteri gram negatif yang paling sering ditemukan pada periodontitis. Daun sirih merah sebagai bahan alami dilaporkan memiliki kandungan senyawa berupa flavonoid, alkaloid, tanin, saponin dan minyak atsiri yang terbukti memiliki efek antibakteri. Tujuan: Mengetahui ada atau tidaknya aktivitas antibakteri ekstrak daun sirih merah (Pipe…
Kidney stone disease (antinefrolithiasis) of calcium stone type is one of the health problems among Indonesian people. The use of diuretic drugs as a treatment for kidney stones can be replaced with natural ingredients to reduce the risk of side effects. Kersen leaves (Muntingia calabura L.) contain a lot of flavanes, flavones, flavanones, flavonols, and chalcones which are included in the flav…
Background: Drug allergy is a hypersensitivity reaction to medications involving immunological mechanisms that can cause clinical manifestations ranging from mild to severe, such as rash, urticaria, and anaphylaxis. Children are a vulnerable group due to their immature immune systems and limited alternative treatment options. This study aimed to determine the distribution of drug allergy incide…
Background: Wound healing is a complex biological process that progresses through the phases of inflammation, proliferation, and remodeling. Cung kediro (Solanum lycopersicum var. cerasiforme) contains lycopene, β–carotene, vitamin C, and flavonoids, which act as potent antioxidants and have the potential to accelerate epithelialization, angiogenesis, and keratinization. This study aimed to …
Introduction: Oxidative stress is an imbalance between free radicals and endogenous antioxidants that plays a role in the pathogenesis of various degenerative diseases. Natural antioxidants from plants, particularly those containing phenolic compounds and flavonoids, have become potential alternatives for the prevention of oxidative stress. Kersen mistletoe leaves contain various secondary meta…
Thrombosis is a leading global cause of cardiovascular diseases. While anticoagulants, antiplatelet agents, and thrombolytic therapies are the standard clinical treatments, iron oxide nanoparticles offer an alternative approach due to their ability to accumulate at sites of inflammation, such as thrombi and atherosclerotic plaques. These nanoparticles can act as photothermal agents, absorbing l…
Thrombosis is a condition that occurs due to an imbalance in the hemostasis system characterized by the formation of a blood clot (thrombus) in the blood vessel wall so that it can cause ischemic stroke disease. The anti-thrombotic drugs commonly used are thrombolytics. These drugs contain fibrinolytic enzymes such as protease enzymes. Pineapple (Ananas comosus (L.) Merr) is known to have an an…
Kegiatan penelitian yang dilakukan di Sungai Saka Formasi Gumai Daerah Negeri Sindang dan sekitarnya, Kecamatan Sosoh Buay Rayap, Kabupaten Ogan Komering Ulu, Provinsi Sumatera Selatan. Lokasi penelitian terbagi menjadi delapan lokasi dengan litologi batulempung karbonat dan batupasir karbonat. Penelitian ini dilakukan untuk mengidentifikasi lingkungan batimetri dan iklim purba melalui analisi…
Barringtonia acutangula or indian oak is a type of tree that are found in many swamps and river banks in Sumatera Selatan region. Determination of total phenolic content, total flavonoid content, antioxidant activity and toxicity of indian oak (Barringtonia acutangula) leaves extract was carried out. Extraction process was carried out by using increasing polarity maceration with n-hexane, ethyl…
Background: Gout is a chronic condition caused by the accumulation of monosodium urate (MSU) crystals due to hyperuricemia, often associated with a diet high in purines, obesity, and other metabolic disorders. Allopurinol is the first-line drug used to lower serum uric acid levels in gout patients. Ensuring the correct dosage of allopurinol is essential to enhance therapeutic effectiveness and …
Pengobatan yang baik berpengaruh pada tingkat pengetahuan, kepatuhan minum obat penurun kadar kolesterol dan kualitas hidup pasien. Tujuan penelitian ini adalah menganalisis hubungan antara tingkat kepatuhan minum obat dengan kualitas hidup pasien hiperkolesterolemia di Rumah Sakit Islam Siti Khadijah Palembang. Desain penelitian dilakukan secara observasional analitik dengan pendekatan cross-s…
Introduction: Myocardial infarction (MI) is a leading cause of global mortality with reperfusion therapy as its the gold standard. However, the following myocardial ischemia-reperfusion injury (MIRI) still lacks effective pharmacologic treatment. Mapping protein interaction networks may help identify herbal-based therapeutic targets related to mitochondria which holds central role in energy met…
This study aims to analyze and assess the compliance of the implementation of the internal control system for drug inventory at the Pharmacy Installation of the Health Office of Ogan Komering Ilir District (IFK OKI). This research employs a qualitative method with a case study approach. The analysis refers to the five components of COSO (Committee of Sponsoring Organizations of the Treadway Com…
Apitherapy adalah pengobatan dengan menggunakan produk lebah madu. Penelitian ini menggunakan propolis sebagai salah satu produk lebah madu yang bertujuan untuk memperoleh data mengenai perbedaan sensasi nyeri dan perubahan ukuran lesi sebelum dan sesudah dilakukan terapi selama 4 hari. Penelitian dilakukan pada masyarakat Kelurahan Rejosari Kecamatan Pangkal Balam Kota Pangkalpinang yang mende…
Penelitian ini beijudul hubungan antara pemanfaatan pengobatan alternatif dan perilaku kesehatan pada masyarakat perkotaan (studi Kelurahan Lebung Gajah Kecamatan Sako Kota Palembang), permasalahan yang akan dibahas adalah (1) bagaimana pemanfaatan pengobatan alternatif pada masyarakat Lebung Gajah? (2) bagaimana perilaku kesehatan pada masyarakat Lebung Gajah Palembang? (3) bagaimana hubungan …
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This research was done to study the ability of tannin degradation by various rumen fluid it was conducted with 3 treatment and 4 replication each (SI - S3). Observed parameters were 1) Total cont bacteria, 2) Tannin concentration and 3) Characterization of rumen microbes and tannin degradation activity. This research had been conducted from Sept 24^ 2007 - Oct 29^ 2007 in Animal Feed and Nutrit…
Pengobatan sendiri merupakan tindakan yang paling banyak dipilih oleh masyarakat Indonesia, termasuk juga di kalangan mahasiswa. Obat analgesik bebas merupakan obat yang banyak digunakan dalam upaya pengobatan sendiri. Namun tindakan pengobatan sendiri harus disertai dengan pengetahuan yang memadai agar upaya pengobatan tersebut bisa efektif dan aman. Pengetahuan juga akan mempengaruhi sikap ma…
Obat antituberkulosis “Fixed Dose Combinatiori” (OAT-FDC) dinilai memberikan beberapa keuntungan praktis dalam meminimalisasikan faktor-faktor yang mempengaruhi keberhasilan pengobatan, obat ini kini sudah direkomendasikan oleh WHO sebagai pendekatan baru dalam pengobatan tuberkulosis paru dan mulai digunakan secara luas. Penggunaan OAT-FDC tergolong masih baru dan data-data keberhasilannya…
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Stenotrophomonas maltophilia is a Gram-negative bacterium that acts as an opportunistic pathogen and is frequently associated with pneumonia and bacteremia. One of the bio-pharmaceutical plants with potential activity against Stenotrophomonas maltophilia infection is karamunting (Rhodomyrtus tomentosa (Aiton) Hassk.), which is widely found in Southeast Asia. The use of karamunting leaf extract …
Background: Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen that frequently causes nosocomial infections and exhibits strong biofilmforming ability as well as high resistance to various antibiotics, including carbapenems. The increasing incidence of MDR-P. aeruginosa highlights the need for alternative antimicrobial agents derived from natural sources. Karamunting leaves (Rhod…
Kenikir (Cosmos caudatus) is plant commonly used as food ingredient and traditional medicine. The method used to measure protein content of kenikir leaves in previous study was relatively unspecific. Warburg–Christian and Bicinchoninic acid assay methods can serve as alternative for measuring protein content of kenikir leaves. This study aimed to compare the protein levels of kenikir (Cosmos …
Background: Cigarettes are one of the leading causes of death worldwide. The number of deaths caused by exposure to cigarette smoke reaches 8 million individuals per year. This can occur because cigarette smoke contains more than 7,000 chemical compounds that can cause damage to body cells due to high levels of reactive oxygen species (ROS), thereby increasing oxidative stress that triggers lip…