POLA PENGGUNAAN ALLOPURINOL PADA PASIEN GOUT ARTRITIS DI PUSKESMAS SEKIP PALE…

Background: Gout arthritis is an inflammatory disease of the joints caused by the deposition of monosodium urate crystals in the joint area, especially the extremities. In pharmacological therapy, allopurinol is the first-line choice in the management of gout, especially asymptomatic, intercritical, and chronic hyperuricemia phases. In Indonesia, especially now there is no data discussed gout a…

PENGETAHUAN, SIKAP, DAN PERILAKU SWAMEDIKASI OBAT BEBAS PADA MAHASISWA FAKULT…

Background: Over-the-counter drug (OTC) is a medicine that can be purchased freely without a doctor's prescription. Students tend to need medicine that can be accessed quickly and efficiently. Thus, the majority of population who do self-medication is mostly students. Unfortunately, there are still many people who do self-medication without being given sufficient education, so knowledge, attitu…

EFEK INHIBISI EKSTRAK N-HEKSANA DAUN BENALU KERSEN (DENDROPHTHOE PENTANDRA (L…

Background. Kersen leaf extract has the effect of inhibiting the xanthine oxidase enzyme and cherry mistletoe leaves also have the same properties considering that they are hemiparasites with their host. This study aims to determine the effect of n-hexane extract from mistletoe cherry leaves on the xanthine oxidase enzyme. Method. This research is an in vitro experimental research. The samples …

HUBUNGAN KADAR ALBUMIN SERUM DAN DERAJAT VARISES ESOFAGUS PADA PASIEN SIROSIS…

Background: Esophageal varices is the most life-threatening complication of portal hypertension in hepatic cirrhosis patients. Around 80% of cirrhosis patients will eventually experience this complication. Non-invasive parameters are needed for early detection of the degree of esophageal varices so that patients with severe varices can be immediately referred for endoscopic examination. In addi…

UJI POTENSI EFEK ANTIOBESITAS EKSTRAK DAUN KELOR (Moringa oleifera L.) PADA M…

Introduction: Obesity is characterized by the abnormal accumulation of fat within the body, resulting from an imbalance between the energy intake and expenditure. Obesity elevates the risk of various chronic diseases, necessitating efforts to prevent and treat this condition. Previous research has revealed that Moringa oleifera leaf extract contains polyphenolic compounds with advantageous prop…

senyawa OBAT: Buku Pelajaran KIMIA FARMASI edisi kedua

Edition

2

ISBN/ISSN

979-420-154-5

Collation

xii, 894 hlm. : ilus. ; 21 cm

Series Title

-

Call Number

615.1 Sch s

OPTIMASI SEDIAAN SUNSCREEN SPRAY GEL EKSTRAK ETANOL DAUN ALPUKAT (Persea amer…

KIN THAT IS EXPOSED TO EXCESSIVE SUN EXPOSURE CAN RESULT IN SEVERAL LOSSES THAT CAN DAMAGE THE SKIN INCLUDING PREMATURE AGING, SKIN DAMAGE BY ULTRAVIOLET RADIATION, AND SUNBURN OR BURNING REACTIONS. SUNSCREEN IS NEEDED TO PROTECT THE SKIN FROM DAMAGE CAUSED BY UV RAYS. ZINC OXIDE IS A PHYSICAL SUNSCREEN AGENT THAT IS OFTEN USED AS AN ACTIVE INGREDIENT IN SUNSCREEN PREPARATIONS. AVOCADO LEAVES H…

OPTIMASI GELLING AGENT PADA SEDIAAN GEL EKSTRAK SAMBILOTO (ANDROGRAPHIS PANIC…

Daun sambiloto (Andrographis paniculata (Burm.f.) Nees) merupakan tanaman yang mengandung senyawa aktif seperti andrografolida (diterpenlactone), flavonoid, asam quinic, steroid, saponin, alkaloid dan tanin yang memiliki potensi sebagai antiinflamasi, antioksidan, antibakteri, dan mempercepat penyembuhan luka. Penelitian ini bertujuan untuk mengoptimasi Gelling Agent pada sediaan gel ekstrak sa…

PENGARUH EKSTRAK ETIL ASETAT DAUN SUKUN (Artocarpus altilis) TERHADAP PERBAIK…

Daun sukun (artocarpus altilis) dilaporkan memiliki kandungan flavonoid yang memiliki aktivitas antioksidan dan antiinflamasi yang berpotensi memperbaiki fungsi ginjal. Penelitian ini bertujuan untuk mengetahui pengaruh variasi dosis terhadap efek nefroprotektif. Parameter yang diamati meliputi volume urin, pH urin, kreatinin serum, ureum serum, protein urin, klirens kreatinin, serta dilakukan …

FORMULASI DAN UJI AKTIVITAS ANTIDIABETES NANOSUSPENSI EKSTRAK DAUN KENIKIR (C…

Kenikir leaves has pharmacological activity as an antidiabetic because it contains flavonoid compounds in the form of quersetin which can become the α-glukosidase enzyme inhibitor so that excess blood glucose level can be lowered. The effectiveness and bioavailability of extracts tend to be low so that the formula in the form of nanosuspension is an option for improving the delivery system whi…

UJI AKTIVITAS ANTIOKSIDAN KOMBINASI EKSTRAK ETANOL DAUN SIRSAK (Annona murica…

Soursop leaf and sapodilla leaf contain secondary metabolit is flavonoid which is antioxidant. The study aimed to the characteristic of the ethanol extract soursop leaf (Annona muricata L.) and sapodilla leaf (Manilkara zapota L.), total flavonoid contents, and antioxidant activity of combine ethanol extract soursoup leaf and sapodilla leaf using DPPH method. The treatment of antioxidant activi…

ANALISIS HUBUNGAN PENGGUNAAN OBAT ANTIPSIKOTIK TERHADAP KEJADIAN EFEK SAMPING…

Skizofrenia merupakan salah satu ganggu jiwa berat yang ditandai dengan kesulitan pada penderita untuk membedakan antara nyata dan tidak nyata dalam kehidupan sehari-hari seperti halusinasi dan delusi. Manajemen terapi yang digunakan pada pasien skizofrenia adalah menggunakan terapi antipsikotik. Efek samping yang sering muncul akibat terapi antipsikotik adalah gejala ekstrapiramidal. Penelitia…

HUBUNGAN RASIONALITAS PENGGUNAAN OBAT TERHADAP OUTCOME KLINIS PASIEN GOUT DI …

Gout is an arthritis disease that occurs due to increased levels of uric acid in the blood (hyperuricemia), causing the deposition of monosodium urate (MSU) crystals in the joints. Rational drug use in gout patients can affect the success of therapy. This study aims to determine the correlation between the rationality of drug use and clinical outcomes in gout patients at RSI Siti Khadijah Palem…

PENGARUH EKSTRAK ETIL ASETAT DAUN NANGKA (Artocarpus heterophyllus) TERHADAP …

Ekstrak etil asetat daun nangka (Artocarpus heterophyllus) mengandung senyawa metabolit sekunder berupa flavonoid yang memiliki aktivitas antioksidan dan antiinflamasi yang berpotensi memperbaiki fungsi ginjal. Penelitian ini bertujuan mengetahui aktivitas perbaikan fungsi ginjal dari ekstrak etil asetat daun nangka (EEADN). Uji aktivitas perbaikan ginjal dilakukan selama 28 hari menggunakan 30…

FORMULASI DAN UJI AKTIVITAS ANTIERITEMA GEL TABIR SURYA EKSTRAK ETIL ASETAT D…

Breadfruit leaves (Artocarpus altilis (Park.) Fosberg) contain flavonoids which have activity and have the potential to act as photoprotective agents because of their ability to absorb UV light. This study aims to determine the effect of variations in the formulation of breadfruit leaf ethyl acetate extract on the effect of activity tests as a sunscreen with Carbomer 940 and Triethanolamine as …

FORMULASI DAN UJI AKTIVITAS ANTIERITEMA KRIM TABIR SURYA EKSTRAK ETIL ASETAT …

Exposure to direct sunlight for a long time can cause damage to the epidermal tissue of the skin which is a factor in the emergence of erythema and causes skin cancer. Sunscreen is a cosmetic product that functions to protect the skin from exposure to UV rays. Breadfruit leaves (Artocarpus altilis) are reported to contain antioxidant compounds which have the potential to be active ingredients f…

OPTIMASI KONSENTRASI TWEEN 80 DAN ETANOL 96% DALAM SEDIAAN NANOEMULSI DAUN SA…

Sambiloto leaves extract (Andrographis paniculata (Burm.f.) Wall. Ex Ness) contains andrographolid and flavonoid main secondary metabolites which have potential as ultraviolet radiation protection and antioxidant activity as photoprotective agents. This research aims to determine the optimization of Tween 80 and Ethanol 96% concentrations to increase their photoprotective and stability. Optimiz…

PENGARUH EKSTRAK ETIL ASETAT DAUN CEMPEDAK (Artocarpus champeden) TERHADAP PE…

Daun cempedak (Artocarpus champeden) mengandung metabolit sekunder berupa flavonoid yang memiliki aktivitas antioksidan dan antiinflamasi yang berpotensi dalam memperbaiki fungsi ginjal. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etil asetat daun cempedak (EEADC) terhadap volume dan pH urin, kadar kreatinin dan ureum serum, kadar protein urin, klirens kretinin dan gamb…

OPTIMASI EKSTRAKSI DAUN GAMBIR (UNCARIA GAMBIR ROXB.) MENGGUNAKAN METODE ULTR…

Catechins compounds in gambier leaves have an antioxidant effect. The purpose of this study is to determine the optimal results of gambir leaf extract and the characteristic of optimal gambier leaf extract. The extraction method used in the study was ultrasoundassisted extraction (UAE). Data analysis was carried out using software design expert 13 with factorial 23. Factors in the extraction pr…

JAMU & KESEHATAN

Edition

-

ISBN/ISSN

978-602-0936-18-5

Collation

ii, 28 hlm.; illus.; 18,5 cm.

Series Title

-

Call Number

615.3 Adi j

HUBUNGAN CURIOSITY DENGAN PENGAMBILAN KEPUTUSAN PADA WANITA PENGGUNA KOSMETIK…

Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara curiosity dengan pengambilan keputusan pada wanita pengguna kosmetik pemutih wajah. Terdapat 4 hipotesis dalam penelitian ini, yaitu adanya hubungan antara curiosity dengan: (1) vigilance; (2) hypervigilance; (3) buckpassing; (4) procrastination pada wanita pengguna kosmetik pemutih wajah. Partisipan pada penelitian ini adalah s…

DAYA ANTIBAKTERI EKSTRAK DAUN NANAS KOTA PRABUMULIH (ANANAS COMOSUS) TERHADAP…

Background: The failure of endodontic treatment is often caused by errors during elimination procedures of Gram-positive bacteria (Enterococcus faecalis) so that it is necessary to use irrigating solutions such as sodium hypochlorite (NaOCl) to eliminate it from the root canal. Prabumulih City’s pineapple leaves (Ananas comosus) are herbal plants that have antibacterial properties due to the …

PENGARUH PENDIDIKAN KESEHATAN MENGGUNAKAN MEDIA VIDEO TERHADAP PENGETAHUAN DA…

The teenager is a transitional phase in which individuals experience rapid changes physically, cognitively, and psychosocially. This change makes a person have the desire to find an identity and perform risky behavior that will result in complex health problems in the teenager. Teenager integrated healthcare center was formed to monitor teenager health in a comprehensive and holistic. However, …

PENGARUH PERMAINAN EDUKASI MONOPOLI BERMAIN ASIK MENGENAL DIRI (BERSINAR) TER…

The psychological impact of breast cancer on patients happens to significantly affect their quality of life, leading to issues such as low self-concept, low self-esteem, anxiety, and fear of death. Low self-esteem can hinder the patient’s treatment process. One potential strategy to address this problem is through the use of health education interventions. The health education media use is Mo…

EVALUASI PENGGUNAAN OBAT PADA PASIEN TUKAK PEPTIK DI INSTALASI RAWAT INAP RSI…

Tukak peptik berupa suatu keadaan rusaknya pada jaringan mukosa, submukosa hingga lapisan otot dari suatu daerah saluran cerna. Tukak peptik merupakan keadaan yang perlu mendapat perhatian yang serius karena prevalensinya yang cukup tinggi. Tukak peptik dapat menimbulkan komplikasi sedikitnya 25% pada kasus perdarahan saluran cerna. Penelitian ini bertujuan mengevaluasi penggunaan obat pada pas…

UJI AKTIVITAS ANTIOKSIDAN FRAKSI ETANOL DAUN SALAM (Syzigium polyanthum [Wigh…

Daun salam (Syzygium polyanthum [Wight.] Walp.) mempunyai banyak khasiat bagi tubuh, salah satu khasiatnya adalah untuk mengatasi penyakit degeneratif. Telah dilakukan penelitian aktivitas antioksidan dari fraksi etanol daun salam secara in vivo dengan mengukur kadar malondialdehid, aktivitas enzim katalase, makroskopik dan histopatologi hati tikus. Metabolit sekunder yang terdapat di dalam dau…

OPTIMASI FORMULA SELF-NANOEMULSIFYING (SNE) EKSTRAK KULIT BUAH KOPI DENGAN ME…

The main problem in the coffee processing process is the handling of coffee waste. Coffee fruit skin is only used as animal feed. Even though coffee peel extract has potential as an antioxidant because it contains flavonoids, especially catechins. Coffee pod extract has low solubility and bioavailability, so it is formulated in a self-nanoemulsifying (SNE) form. SNE) is able to increase solubil…

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAN FRAKSI DAUN KARDIA (BELLUCIA PEN…

Oxidative stress can cause degenerative diseases such as cancer, diabetes, heart disease and stroke, antioxidants are needed to overcome this. One of the Indonesian plants that has the potential as an antioxidant is cardia (Bellucia pentamera Naudin). Based on the results of the phytochemical screening, kardia leaves contain secondary metabolites which have pharmacological activity as antioxida…

UJI TOKSISITAS SUBKRONIS FRAKSI ETIL ASETAT DAUN MELINJO (GNETUM GNEMON LINN.…

Daun melinjo memiliki aktivitas farmakologis sebagai antidiare, antihiperlipidemia, antidiabetes, antioksidan, dan diuretik. Tujuan penelitian ini untuk mengetahui toksisitas subkronis fraksi etil asetat daun melinjo terhadap tikus putih jantan galur Wistar. Pada penelitian ini dibagi menjadi 5 kelompok yaitu kelompok kontrol (Na-CMC 0,5%) dan 4 kelompok perlakuan yang terdiri dari dosis 40 mg/…

UJI ANTI INFLAMASI TRANSDERMAL PATCH EKSTRAK DAUN CEMPEDAK (ARTOCARPUS INTEGE…

Inflamasi dapat menyebabkan rasa kurang nyaman pada penderita akibat edema yang ditimbulkan, sehingga diperlukan obat antiinflamasi. Daun cempedak mengandung flavonoid yang berpotensi sebagai antiinflamasi dengan kemampuannya menghambat pembentukan prostaglandin. Proses penghantaran zat aktif akan lebih efektif apabila dilakukan dalam bentuk suatu sediaan seperti sediaan transdermal patch. Komp…