Children with Virtual Autism (VA) are at risk of developing social, emotional, and communication disorders due to excessive exposure to digital media. This study aims to determine the prevalence and risk factors of VA in children. An observational analytic study with a cross-sectional design was conducted at RSUP Dr. Mohammad Hoesin Palembang from February 2025 to June 2025. The study involved …
Background: Vitamin D deficiency is an emergency problem in Indonesia with a prevalence rate of 33% in all children and young adults and can affect the function in the field of orthopedics and traumatology, especially in the physical performance of the musculoskeletal system even there was controversial in level of molecular theory. This study aims to determine correlation of serum vitamin D le…
SAC dan CPA merupakan prosedur ACDF yang sering dilakukan pada pasien dengan stenosis kanalis servikalis. Kedua metode prosedur pembedahan tersebut menunjukkan fusion rate yang sebanding. Penelitian ini bertujuan untuk menganalisis asosiasi antara prosedur ACDF-SAC dan ACDF-CPA dengan fusion rate pada single level degenerative subaxial cervical stensosis di Rumah Sakit Umum Dr Mohammad Hoesin P…
Background: Nasopharyngeal carcinoma (NPC) is one of the most common malignancies in Indonesia, with the majority of patients presenting at an advanced stage. Vitamin D has been suggested to play a role in improving treatment response, but clinical evidence remains limited. This study aimed to evaluate the effectiveness of vitamin D supplementation on treatment response in NPC patients undergoi…
Latar Belakang: Karsinoma nasofaring merupakan keganasan epitel mukosa yang sering ditemukan di Asia Tenggara, termasuk Indonesia, dengan tingkat kesintasan rendah akibat sifatnya yang agresif dan penyebaran limfatik maupun hematogen yang cepat. Penanda proliferasi Ki67 berperan penting dalam menilai aktivitas pembelahan sel tumor, memprediksi prognosis, serta mengevaluasi respons terhadap kemo…
Background: High-resolution computed tomography (HRCT) imaging of the temporal bone prior to mastoidectomy is a routine examination in the field of Otorhinolaryngology–Head and Neck Surgery (ENT-HNS). HRCT findings play an important role in the medical and surgical management of patients with chronic suppurative otitis media (CSOM). In addition, HRCT can serve as the basis for planning the su…
Background: Acute diffuse otitis externa is an inflammation of the skin and subcutaneous tissue of the external auditory canal, commonly caused by bacterial infection, particularly Pseudomonas aeruginosa and Staphylococcus aureus. Treatment involves ear canal cleaning, pain control, and topical antibiotic therapy using ear tampons. Single antibiotic tampons effectively treat infection but lack …
Introduction: Cardiovascular disease is the leading cause of morbidity and mortality in chronic haemodialysis patients. Conventional assessment of systolic function using left ventricular ejection fraction (LVEF) is often less sensitive in detecting subclinical myocardial dysfunction that impacts short-term prognosis. Left ventricular Global Longitudinal Strain (GLS) is suspected to be closely …
Background: Sarcopenia is a progressive skeletal muscle disorder characterized by a decline in muscle strength, mass, and physical performance, leading to increased fall risks and reduced quality of life in the elderly. The pathogenesis is driven by "inflammaging," particularly elevated levels of Interleukin 6 (IL-6). Given the rising geriatric population in Palembang, early detection through c…
Background: As people age, the human body undergoes physiological changes, including a progressive reduce of skeletal muscle mass and strength, known as sarcopenia. The diagnosis of sarcopenia is based on calf circumference screening, also measurement of muscle mass, muscle strength, and physical performance. The primary factors contributing to sarcopenia are systemic inflammation and oxidative…
Background Elderly individuals represent a population with a high potential for a decline in the quantity and quality of skeletal muscles, a condition known as sarcopenia. Muscle quantity refers to the reduction in muscle mass, while muscle quality can be assessed through muscle strength and physical performance as age advances. Sarcopenia significantly reduces the ability to perform daily func…
Background: The presence of a malignant pleural effusion (MPE) indicates advanced stage in malignancy, which severely compromises in a poor prognosis. The LENT score has been developed as a prognostic tool for MPE, yet its association with pleural effusion progression and six-month survival has not been thoroughly evaluated, particularly in Indonesia. Methods: This prospective cohort study incl…
Background: Type 2 diabetes mellitus (T2DM) is characterized by hyperglycemia resulting from impaired insulin secretion or insulin resistance, with chronic low-grade inflammation playing a role in its pathogenesis. Diacerein has anti-inflammatory effects and improves insulin sensitivity; however, clinical evidence in Indonesia remains limited. Objective: To evaluate the effect of adding diacere…
Background: Acute Coronary Syndrome (ACS) is one of the leading causes of mortality and hospitalization due to cardiovascular disease. Variations in patient characteristics and the presence of metabolic risk factors may influence the occurrence and prognosis of ACS. Therefore, understanding the profile of ACS patient characteristics is essential as a basis for preventive planning and clinical s…
Background: STEMI is an acute condition caused by obstruction of blood flow to the heart, leading to cardiomyocyte necrosis. This process begins with the formation of atherosclerotic plaques that cause total occlusion of the coronary artery lumen, resulting in myocardial ischemia. When transmural ischemia lasts for 20–40 minutes, cardiomyocyte necrosis occurs. Methods: This study aimed to des…
Background: Type 2 Diabetes Mellitus (T2DM) was a chronic metabolic disease with an increasing prevalence, accompanied by hepatic complications such as Metabolic Dysfunction–Associated Fatty Liver Disease (MAFLD). The duration of T2DM affected the severity of metabolic disturbances, insulin resistance, and hepatic fat accumulation. However, data on the incidence of MAFLD at RSUP Dr. Mohammad …
Background. Low back pain (LBP) is one of the most common musculoskeletal complaints and can adversely affect physical function, quality of life, and patient productivity. Vitamin D deficiency, assessed through serum 25-hydroxyvitamin D (25-OH D) levels, plays a role in pain modulation, muscle function, and inflammatory responses, and is suspected to be associated with LBP occurrence. This stud…
Urothelial carcinoma is the most common malignancy of the urinary tract and exhibits a wide range of clinicopathological characteristics that influence prognosis and patient management. Local data regarding the clinicopathological characteristics of urothelial carcinoma in Palembang remain limited; therefore, this study was conducted to provide a more representative overview. This study was a d…
Background: Chronic Kidney Disease (CKD) is a progressive condition that requires long-term hemodialysis treatment. Hemodialysis results are greatly influenced by vascular access, especially Arteriovenous Shunt (AV Shunt) as permanent access and Double Lumen Catheter (CDL) as temporary access. The difference between the patient's characteristics and the clinical condition is often a factor in t…
Background: Bone marrow trephine biopsy is an essential diagnostic procedure for hematological diseases through assessment of morphology, fibrosis, cellularity, and tumor involvement. Since 2023, Dr. Mohammad Hoesin General Hospital Palembang has routinely performed bone marrow biopsies; however, clinicohistopathological data remain limited. This study aimed to describe the bone marrow clinicoh…
Background: Coronary Artery Bypass Graft (CABG) is a myocardial revascularization procedure aimed at restoring blood flow to the heart in patients with coronary artery disease. Postoperative evaluation of functional capacity is important to assess the effectiveness of cardiac recovery, particularly during phase I of cardiac rehabilitation. The Six-Minute Walk Test (6MWT) is a simple and safe me…
Background: Diffuse large B-cell lymphoma (DLBCL) is the most common subtype, with 150,000 new cases yearly. Roughly 40% of patients who receive rituximab in addition to vincristine, cyclophosphamide, doxorubicin, and prednisone treatment have primary refractory disease or recurrence. Although the Ann Arbor stage could determine DLBCL prognosis, new biomarkers are needed to stratify patient pro…
Background: Sarcopenia is a condition characterized by a decrease in muscle mass accompanied by a reduction in muscle strength and/or physical performance, which frequently occurs in older adults and leads to an increased risk of falls, dependency, cognitive and cardiopulmonary function decline, lower quality of life, mortality, and high healthcare costs. Calf circumference is recommended as a …
Background: Morbus Hansen (MH), also known as leprosy, is a chronic infectious disease caused by Mycobacterium leprae that primarily affects the skin and peripheral nerves. Despite global elimination efforts, MH remains a public health problem in Indonesia. Histopathological examination plays an essential role in establishing the diagnosis and determining the disease spectrum. This study aimed …
Background: Anemia is a common health problem among adolescent girls and can lead to decreased productivity, learning concentration, and academic performance. Medical students are expected to have good knowledge and attitudes toward anemia prevention; however, such understanding is not always reflected in preventive behaviors. Objective: This study aimed to determine the relationship between kn…
Background: The use of contact lenses continues to increase among university students, both for cosmetic purposes and refractive correction. However, improper usage behavior may increase the risk of complications, particularly when hygiene and wearing duration are not adequately managed. This study aimed to describe the compliance level regarding contact lens use among medical students at the F…
Background: Disorders of Sexual Development (DSD) is a congenital condition with a prevalence of 1:4,500–5,500 live births that can result in ambiguous genitalia and endocrine emergencies. External genitalia examination in newborns is often not comprehensive, risking sex assignment errors and diagnostic delays. This study aims to provide an overview of external genitalia features in pediatric…
Background: Leukemia is a hematopoietic malignancy characterized by abnormal leukocyte production in the bone marrow. The mortality and incidence rates of children with leukemia are the highest among all childhood cancers. One type of leukemia is acute myeloid leukemia (AML). About 20% of AML cases occur in children. The outcomes of children with AML may be influenced by several factors. Object…
Background. Overcrowded, humid, and unhygienic prison environments increase the risk of skin diseases among inmates. Epidemiological data on skin diseases in Indonesian prisons are still limited; therefore, this study aims to describe the pattern of skin diseases among inmates at the Class IIA Women’s Penitentiary in Palembang. Methods. This study was an analytical observational study with a …
Background: Nutritional problems among preschool-aged children remain a public health concern because they affect children’s growth and development. The Free Nutritious Meal Program (Makan Bergizi Gratis, MBG) is a school-based nutrition intervention initiated by the government to improve the quality of children’s dietary intake. However, data on changes in the anthropometric status of kind…