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This research was done to study the ability of tannin degradation by various rumen fluid it was conducted with 3 treatment and 4 replication each (SI - S3). Observed parameters were 1) Total cont bacteria, 2) Tannin concentration and 3) Characterization of rumen microbes and tannin degradation activity. This research had been conducted from Sept 24^ 2007 - Oct 29^ 2007 in Animal Feed and Nutrit…
Pengobatan sendiri merupakan tindakan yang paling banyak dipilih oleh masyarakat Indonesia, termasuk juga di kalangan mahasiswa. Obat analgesik bebas merupakan obat yang banyak digunakan dalam upaya pengobatan sendiri. Namun tindakan pengobatan sendiri harus disertai dengan pengetahuan yang memadai agar upaya pengobatan tersebut bisa efektif dan aman. Pengetahuan juga akan mempengaruhi sikap ma…
Obat antituberkulosis “Fixed Dose Combinatiori” (OAT-FDC) dinilai memberikan beberapa keuntungan praktis dalam meminimalisasikan faktor-faktor yang mempengaruhi keberhasilan pengobatan, obat ini kini sudah direkomendasikan oleh WHO sebagai pendekatan baru dalam pengobatan tuberkulosis paru dan mulai digunakan secara luas. Penggunaan OAT-FDC tergolong masih baru dan data-data keberhasilannya…
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Stenotrophomonas maltophilia is a Gram-negative bacterium that acts as an opportunistic pathogen and is frequently associated with pneumonia and bacteremia. One of the bio-pharmaceutical plants with potential activity against Stenotrophomonas maltophilia infection is karamunting (Rhodomyrtus tomentosa (Aiton) Hassk.), which is widely found in Southeast Asia. The use of karamunting leaf extract …
Background: Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen that frequently causes nosocomial infections and exhibits strong biofilmforming ability as well as high resistance to various antibiotics, including carbapenems. The increasing incidence of MDR-P. aeruginosa highlights the need for alternative antimicrobial agents derived from natural sources. Karamunting leaves (Rhod…
Kenikir (Cosmos caudatus) is plant commonly used as food ingredient and traditional medicine. The method used to measure protein content of kenikir leaves in previous study was relatively unspecific. Warburg–Christian and Bicinchoninic acid assay methods can serve as alternative for measuring protein content of kenikir leaves. This study aimed to compare the protein levels of kenikir (Cosmos …
Background: Cigarettes are one of the leading causes of death worldwide. The number of deaths caused by exposure to cigarette smoke reaches 8 million individuals per year. This can occur because cigarette smoke contains more than 7,000 chemical compounds that can cause damage to body cells due to high levels of reactive oxygen species (ROS), thereby increasing oxidative stress that triggers lip…
Background. Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia, requiring rational pharmacological therapy. Metformin is the first-line therapy for type 2 DM as recommended by WHO and the National Formulary. Defined Daily Dose (DDD) measurement enables a quantitative evaluation of drug use. However, studies on DDD for metformin in South Sumatra remain limited.…
Cervical cancer is the main cause of cancer death among woman and the third most cancer case in the world. High expression of VEGF in cervical cancer is linked to a poor prognosis, therefore anti-VEGF therapy has an important role in cervical cancer resolution. Several studies show that emodin inhibit proliferation, migration, and a formation of endothelial cells stimulated by VEGF. This resear…
This research explores how ASEAN plays a role in tackling the threat of narcotics trafficking from the Golden Triangle, an area that includes Laos, Myanmar, and Thailand For years, this region has been one of the world's major drug-producing centers, creating challenges not only for Southeast Asia but also for other regions beyond. To analyze this issue, the study draws on Clive Archer's framew…
Gout arthritis is an inflammatory joint condition caused by uric acid crystal accumulation. The inflammatory mechanism involves complex pathways that increase Reactive Oxygen Species (ROS) levels. Muntingia calabura L. leaves contain bioactive compounds, such as flavonoids, which are known to reduce ROS production by mitigating pro-inflammatory signaling pathways. This study aims to evaluate th…
Indonesia merupakan salah satu negara dengan kekayaan hayati terbesar di dunia yang memiliki lebih dari 30.000spesies tanaman tingkat tinggi. Hingga saat ini tercatat 7000 spesies tanaman telah diketahui khasiatnya namun kurang dari 300 tanaman telah diketahui bahan baku farmasi secara regular. Namun, isu besar yang menjadi pemikiran pemerintah Indonesia saat ini adalah bagaimana menjamin obat …
Zaman dahulu, pengobatan menjadi aspek yang diutamakan oleh banyak orang untuk mencapai hidup sehat. Namun, sekarang orang cenderung memilih tindakan pencegahan, karena biaya yang dibutuhkan relatif lebih rendah.Tubuh dapat membuat sendir sebagian kecil zat gizi, tetapi sebagian besar tidak dapat dibuat di dalam tubuh sehingga harus diperoleh dari luar (makanan). Zat gizi jenis ini disebut zat …
Zaman dahulu, pengobatan menjadi aspek yang diutamakan oleh banyak orang untuk mencapai hidup sehat. Namun, sekarang orang cenderung memilih tindakan pencegahan, karena biaya yang dibutuhkan relatif lebih rendah.Tubuh dapat membuat sendir sebagian kecil zat gizi, tetapi sebagian besar tidak dapat dibuat di dalam tubuh sehingga harus diperoleh dari luar (makanan). Zat gizi jenis ini disebut zat …
Introduction: Sepsis remains a leading cause of mortality in intensive care units. Fluid resuscitation is the cornerstone of management; however, excessive volume may exacerbate inflammation, activate necroptosis, and aggravate organ injury. This study aimed to evaluate the effect of different fluid resuscitation volumes on inflammation, necroptosis, and renal injury in a lipopolysaccharide (LP…
This research discusses the illness behavior of Miftahuayifa patients in Pasar IVillage, Aluara Enim Regency (case study of Miftahusyifa Alternative MedicinePondak). The aim of this research it to analyse und understand the illnestbehavior of Afflahusyifa patients. The results of this research show that manyprople choose Miftakutyifa Alternative Aledicine Pondok at a treatment mediumbecause the…
Background: The World Health Organization (WHO) states that malocclusion ranks third among the most common oral health problems after dental caries and periodontal disease. The global prevalence of malocclusion among children and adolescents is 56%, with no significant gender differences. Objective: To determine the variation of skeletal patterns in orthodontic patients at RSKGM, South Sumatra …
Background: Tuberculosis is a chronic disease which one of the keys to successful treatment is patient adherence to taking medication every day without missing a day. Patients who do not adhere to their anti-tuberculosis medication are at risk of therapy failure, which can lead to a relapse of tuberculosis in the future or even lead to the risk of anti-tuberculosis drug resistance. One effort t…
HIV/AIDS is a disease for which no cure has yet been found. However, there is an effective treatment to manage the virus, known as Antiretroviral Therapy (ART). Consistent ART can suppress the amount of HIV virus to undetectable levels. People living with HIV (PLHIV) who achieve viral suppression maintain a strong immune system, enjoy a better quality of life, and have a lower likelihood of tra…
Indonesi amerupakan negara yang kaya akan keanekagaragaman hayati. Terdapat puluhan ribu tanaman di tanah air, dan sekitar 2.500 diantaranya masuk sebagai kategori tanaman obat. Tanaman obat dipilih sebagai alternatif karena dipicu oleh mahalnya biaya pengobatan kimiawi dan efek samping dalam jangka panjang obat kimiawi. Walaupun dampak kesembuhannya lebih lama dari pengobatan medis, tetapi pen…
Infections caused by antibiotic-resistant bacteria, particularly carbapenem-resistant Pseudomonas aeruginosa (CRPA), have become a significant global health issue. Pseudomonas aeruginosa is a common nosocomial pathogen that often demonstrates resistance to many antibiotics. Given the rising cases of antibiotic resistance, alternative treatments are needed, one of which involves utilizing the po…
Latar Belakang: Pasien dengan penurunan kesadaran yang menggunakan ventilator mekanik di ruang intensif memiliki risiko tinggi mengalami Ventilator Associated Pneumonia (VAP). Kondisi ini disebabkan oleh gangguan refleks batuk dan mekanisme pertahanan jalan napas yang memudahkan aspirasi sekret orofaring serta kolonisasi bakteri patogen. Upaya pencegahan VAP dapat dilakukan melalui penerapan VA…
Osteoporosis merupakan penyakit sistemik yang ditandai oleh penurunan densitas tulang (BMD) dan kerusakan mikroarsitektur tulang, yang meningkatkan risiko fraktur. Terapi bisfosfonat, termasuk ibandronat dan zoledronat, merupakan salah satu terapi untuk meningkatkan BMD dan mengurangi insidensi fraktur. Penelitian ini bertujuan membandingkan nilai BMD sebelum dan setelah terapi bisfosfonat pada…
One of the obstacles in tilapia cultivation is the Aeromonas hydrophila bacteria that causes Motile Aeromonas Septicemia (MAS) disease. This disease can be overcome by using natural ingredients. One of the natural ingredients that can be used to treat bacterial diseases in fish is the stem of brotowali (Tinospora crispa L.). The use of the stem of brotowali has been proven in vitro to inhibit A…
Excessive free radicals can cause oxidative stress, leading to various degenerative diseases. Natural antioxidants derived from plants have the potential to counteract these effects. Nypa fruticans fiber contains high levels of polyphenols, making it a potential source of antioxidants that can be formulated into lozenges as a practical and consumer-friendly dosage form. This study aimed to desc…
Untuk mendapatkan kondisi sehat tidak harus tergantung dokter, atau tidak harus diatasidengan obat. Berbagai penyakit tidak harus diatasi dengan obat atau upaya-upaya kuratif lain, apabila dapat dilakukan tanpa obat. Gaya hidup sehat harus diterapkan dalam perilaku sehari-hari. Perilaku hidup sehat mencakup beberapa hal, antara lain; makan dengan menu seimbang, olahraga secara teratur, tidak me…
Pemakaian tanaman obat untuk mengatasi berbagai masalah kesehatansaat ini mulai kembali menjadi tren dalam masyarakat di berbagai belahan dunia. “Back to Nature” pun sudah familiar terutama di kalangan masyarakat perkotaan. Sangat tidak tepat membandingkan manakah yang lebih baikantara obat-obatan konvensional atau modern dengan obat tradisional. Cara kerja obat tradisional tidaklah cepat,…