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KARAKTERISASI LIPOSOM PHOTOSENSITIZER PEMBAWA EKSTRAK KASAR NANAS (Ananas com…
Thrombosis is a condition that occurs due to an imbalance in the hemostasis system characterized by the formation of a blood clot (thrombus) in the blood vessel wall so that it can cause ischemic stroke disease. The anti-thrombotic drugs commonly used are thrombolytics. These drugs contain fibrinolytic enzymes such as protease enzymes. Pineapple (Ananas comosus (L.) Merr) is known to have an an…
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- xix, 98 hlm.; ilus.; tab.; 29 cm.
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- T1842462025
OPTIMASI GREEN SYNTHESIS NANOPARTIKEL Ag-Fe3O4 MENGGUNAKAN EKSTRAK AIR BUNGA …
Thrombosis caused by blood clot formation can lead to serious complications. Conventional therapies carry a risk of bleeding, making photothermal therapy based on optical-magnetic nanoparticles such as AgNO₃ and Fe₃O₄ a safer alternative. These nanoparticles are synthesized via green synthesis using butterfly pea flower (Clitoria ternatea L.) extract, which contains flavonoids and anthocy…
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- xx, 175 hlm.; ilus.; tab.; 29 cm.
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- T1841272025
EFEK TERATOGENIK FRAKSI ETIL ASETAT DAUN MELINJO (Gnetum gnemon L.) PADA FETU…
One of the special toxicity tests is the teratogenic test which is carried out to obtain information on the presence of fetal abnormalities that occur due to the administration of test preparations during the formation of fetal organs (organogenesis period) and to complete safety data from the melinjo plant. The doses given were 69.48, 104.22, 138.96 and 173.7 mg/kgBW. The administration of the…
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- xvi, 107 hlm.; ilus.; 29 cm
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- T1590302024
EFEK TERATOGENIK FRAKSI ETANOL DAUN KERSEN (Muntingia calabura L.) PADA FETUS…
Kersen leaves (Muntingia Calabura L) contain secondary metabolite compounds alkaloids, flavonoids and tanins. The use of herbal medicine during pregnancy needs to be considered because the drug can cross the placenta so that it can cause teratogenic effects on the fetus. Teratogenic toxicity research on the ethanol fraction of kersen leaves (Muntingia Calabura L) has been conducted to determine…
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- xiv, 165 hlm.; ilus.; 29 cm
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- T1590292024
FORMULASI DAN EVALUASI SEDIAAN ACNE PATCH TRANSDERMAL EKSTRAK ETANOL DAUN CAB…
Acne is a condition characterized by the accumulation of sebum from sebaceous glands in the skin layers, which often stimulates the growth of acne-causing bacteria, such as Staphylococcus aureus. Acne treatment can be performed using acne patches; however, commercial acne patches are only capable of absorbing sebum without providing antibacterial activity. This study aimed to enhance therapeuti…
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- xvi, 107 hlm.; ilus.; tab.; 29 cm.
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- T1861272025
FORMULASI DAN UJI ANTIOKSIDAN ORALLY DISSOLVING FILM EKSTRAK ETANOL BUNGA K…
Bunga kecombrang (Etlingera elatior) dikenal sebagai bunga khas Asia tenggara famili Zingiberaceae dengan warna merah menyala dan bau khas. Pemanfaatan sediaan orally dissolving film (ODF) dapat menetralisir rasa asam pada bunga kecombrang. Variasi konsentrasi ekstrak etanol bunga kecombrang 0,5%, 0,6%, 0,7%. Evalusi sediaan untuk menentukan formula terbaik meliputi organoleptis, ketebalan, bob…
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- xiii, 87 hlm.; ilus.; 29 cm
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- T1598302024
ISOLASI MINYAK ATSIRI PADA TANAMAN GAMBIR (Uncaria gambir Roxb) DAN INDETIFIK…
Essential oil is one of the non-oil and gas export commodities, gambir is one of the sap-producing plants used for industrial and pharmaceutical purposes, how much gambir essential oil and yield obtained and what components are contained in gambir essential oil, and how much yield is obtained, knowing the components contained in gambir essential oil (Uncaria Gambir Roxb), the research method us…
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- xiv, 58 hlm.; ilus.; 29 cm
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- T1595682024
ANALISIS DRUG RELATED PROBLEMS (DRPs) PADA PASIEN HIPERLIPIDEMIA DENGAN KOMPL…
Hyperlipidemia is a metabolic disorder that acts as a major risk factor for cardiovascular disease. This condition is often accompanied by various complications such as hypertension, diabetes mellitus, and ischemic heart disease, which causes higher complexity of therapy. The complexity of treatment in hyperlipidemia patients increases the potential for Drug-Related Problems (DRPs), which can a…
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- xxvii, 115 hlm.; ilus.; tab.; 29 cm.
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- T1859012025
UJI STIMULASI PROBIOTIK Bifidobacterium longum DENGAN EKSTRAK ETANOL DAUN PUT…
This study aims to evaluate the potential of ethanol extract of putat leaves (Barringtonia acutangula) in stimulating the growth of probiotic Bifidobacterium longum and test its ability to inhibit the growth of pathogenic Escherichia coli bacteria. Bifidobacterium longum is one of the lactic acid bacteria that are beneficial for human gut health, while E. coli bacteria are known as opportunisti…
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- xx, 128 hlm.; ilus.; tab, 29 cm
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- T1806912025
FORMULASI SEDIAAN SPANSULE EKSTRAK ETANOL DAUN PUTAT (Barringtonia acutangula…
Diarrhea caused by Escherichia coli infections remains a significant public health problem in developing countries, including Indonesia. Overuse of antibiotics can lead to resistance, so alternatives are needed. Putat leaves (Barringtonia acutangula) contain the flavonoid quercetin, which has prebiotic and antibacterial potential. This study aims to investigate the effect of putat leaf extract …
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- xvii, 64 hlm.; ilus.; tab.; 29 cm.
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- T1806002025
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAN FRAKSI HERBA SIRIH CINA (peperomia pell…
Chinese betel leaf (peperomia pellucida) contains secondary metabolite compounds such as flavonoids and terpenoids that have potential as antioxidants. This study aims to determine the effect of giving extracts and fractions of Chinese betel herb invivo on male Wistar rats induced oxidative stress by carbon tetrachloride (CCl4). The 30 test animals were divided into 6 treatment groups, namely t…
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- xvi, 52 hlm.; ilus.; tab, 29 cm
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- T1795672025
UJI AKTIVITAS ANTIDEPRESAN EKSTRAK ETANOL DAUN AKASIA (acacia mangim wild) TE…
Acacia leaves (Acacia Mangium Wild) contain secondary metabolite compounds of flavonoids in the form of quercetin which have the potential as antidepressants. This study aims to determine the effect of giving ethanol extract of acacia leaves and its effective dose on antidepressant activity. This study used 30 test animals which were divided into 6 groups, namely, the normal group (1 NaCMC with…
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- xvi, 48 hlm.; ilus.; tab, 29 cm
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- T1802672025
EVALUASI PENGARUH WAKTU TUNGGU RESEP TERHADAP TINGKAT KEPUASAN PASIEN RAWAT J…
Pharmaceutical services are an important aspect of health facilities that directly affect patient satisfaction, one such service is prescription services. Patients often complain about waiting time for prescription services because it impacts their experience obtaining health services. The objective of this study evaluates how waiting time towards prescription services affects outpatient satisf…
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- xvi, 125 hlm.; ilus.; tab, 29 cm
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- T1806392025
STUDI IN SILICO EKSTRAK BUNGA KECOMBRANG (Etlingera Elatior) SEBAGAI ANTIBAKT…
Staphylococcus aureus infection is caused by a bacterium that colonizes various organs in the human body, particularly the upper respiratory tract, including the skin, nasal cavity, axilla, and inguinal area. The emergence of antibiotic-resistant S. aureus, known as MRSA and VRSA, presents a significant challenge in the treatment of such infections. Natural products, such as the torch ginger fl…
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- xvii, 64 hlm.; ilus.; tab, 29 cm
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- T1805082025
UJI TOKSISITAS SUBKRONIS EKSTRAK ETANOL DAUN KENCANA UNGU (Ruellia tuberosa L…
Daun kencana ungu (Ruellia tuberosa L.) merupakan salah satu tanaman yang dimanfaatkan secara luas sebagai obat tradisional. Daun kencana ungu memiliki aktivitas farmakologis sebagai antihiperglikemia, antidiabetes, dan antihipertensi. Penelitian ini dilakukan dengan tujuan untuk mengetahui toksisitas subkronis ekstrak etanol daun kencana ungu terhadap tikus putih jantan galur Wistar. Pada pene…
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- xxi, 107 hlm.; ilus.; 29 cm
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- T1426592024
UJI DAYA ANTIOKSIDAN EKSTRAK DAN FRAKSI-FRAKSI PADA TANAMAN PALIASA (Kleinhov…
Paliasa (Kleinhovia hospita L.) belongs to Malvaceae family with high potential as a medicinal plant because it contains flavonoids,tannins,saponins, steroids and phenolic compounds. This study aims to measure total phenolic content and antioxidant power in extracts and fractions of stem bark, leaves, and root bark of Paliasa and the correlation between antioxidant and total phenolic. Testing t…
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- xviii, 132 hlm.; ilus.; 29 cm
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- T1430042024
OPTIMASI DAN UJI AKTIVITAS ANTIBAKTERI TRANSFERSOM FRAKSI ETIL ASETAT DAUN SI…
Daun singkong (Manihot esculenta Crantz.) terbukti sebagai antibakteri karena kandungan senyawa rutin yang tinggi. Transfersom mampu berpenetrasi melintasi stratum korneum untuk meningkatkan efek antibakteri senyawa rutin pada fraksi etil asetat daun singkong dengan hidrofilisitasnya. Penelitian ini bertujuan untuk mengoptimalkan formula transfersom fraksi etil asetat daun singkong dengan varia…
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- xx, 135 hlm.; ilus.; 29 cm
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- T1412992024
FORMULASI DAN UJIAKTIVITAS ANTIBAKTERI TRANSDERMAL PATCH FRAKSI ETIL ASETAT D…
Transdermal patch was chosen to manage the delivery system of the antibacterial compound in cassava leaves, which is rutin, that is hydrophilic. Plasticizer is one of the additional ingredients of transdermal patches that can maintain the bioavailability of a drug. Transdermal patch formulation with active cassava leaf ethyl acetate fraction ingredients and 3 variations of PEG-400 concentration…
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- xix, 118 hlm.; ilus.; 29 cm
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- T1421242024
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAN FRAKSI DAUN GELAM (MELALEUCA LEU…
Free radicals are dangerous because they can cause degenerative disease. Free radicals can be neutralized by antioxidants. Plants that has potential as an antioxidant is gelam (Melaleuca leucadendra (L.) L.). Gelam leaves contain phenolics, flavonoids, steroids, triterpenoids, tannins, and saponins that have pharmacological activity as antioxidants. The study aimed to determine the characterist…
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- xxii, 179 hlm.; ilus.; 29 cm
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- T1416672024
FORMULASI DISPERSI PADAT IBUPROFEN DENGAN NATRIUM ALGINAT DAN VARIASI KITOSAN…
Ibuprofen is included in the Biopharmaceutical Classification System (BCS) Class II, namely drugs with irregular, slow and incomplete absorption properties. The combination of chitosan polymer with sodium alginate will increase the solubility of ibuprofen without causing systemic toxicity. Making a solid dispersion of ibuprofen using the co-grinding technique is carried out with the aim of redu…
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- xvi, 88 hlm.; ilus.; 29 cm
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- T1422962024
KLASIFIKASI PENYAKIT STROKE MENGGUNAKAN METODE NAIVE BAYES DAN FUZZY NAIVE BA…
A stroke is a nerve funcion that results from a blockage caused by blood clots and causes the oxygen and nutrients in the brain to suffer tissue damage. This study uses the Naïve Bayes and Fuzzy Naïve Bayes method based on Repeated Split Validation Resampling and variable selection use Chi square to classify stroke disease. The data used on this research is a Stroke Prediction Dataset from Ka…
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- xv, 75 hlm.; ilus.; 29 cm
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- T1317042024
UJI DAYA ANTIOKSIDAN EKSTRAK DAN FRAKSI-FRAKSI TANAMAN HARENDONG BULU (Miconi…
Harendong Bulu (Miconia crenata (Vahl) Michelang.) contains secondary metabolites including flavonoids, saponins, tannins, steroids, triterpenoids, and phenolics. Phenolic compounds contained in harendong bulu are known to have antioxidant power. The purpose of this study was to measure total phenolic content and antioxidant power of extracts and fractions from stems, leaves, and roots of haren…
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- xvii, 122 hlm.; ilus.; 29 cm
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- T1429842024
FORMULASI DAN KARAKTERISASI FISIK SEDIAAN KRIM GEL ANTI ACNE EKSTRAK MINYAK J…
Acne vulgaris is often a skin problem that can be caused by the bacteria Propionibacterium acnes. A natural ingredient that can inhibit the growth of P. acnes bacteria is Thymoquinone which is contained in black cumin oil. A combination of HPMC as a gelling agent and black cumin oil as an anti-acne with 3 kinds of formulas with different concentrations of HPMC and black cumin. The aim of this r…
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- xv, 55 hlm.; ilus.; 29 cm
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- T1456592024
EVALUASI PENGGUNAAN OBAT PADA PASIEN BEDAH SESAR (Sectio Caesarea) DI RSUD SI…
Bedah sesar (Sectio Caesarea) adalah suatu tindakan medis untuk melahirkan seorang bayi dengan cara penyatan pada dinding abdomen dan uterus wanita. Pemberian antibiotik profilaksis dapat mencegah terjadinya infeksi luka operasi (ILO) dan pemberian analgesik dapat mengurangi rasa nyeri yang dirasakan paska bedah sesar. Apabila tidak diberikan antibiotik dan analgesik besar resiko persalinan bed…
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- xix, 117 hlm.; ilus.; 29 cm
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- T1418692024
EVALUASI PENGGUNAAN ANTIBIOTIK SECARA KUALITATIF DAN KUANTITATIF PADA PASIEN …
Diare merupakan salah satu masalah kesehatan global termasuk di Indonesia, khususnya pada anak. Pada tahun (2017) World Health Organization mencatat bahwa sekitar 1,7 milliar anak balita meninggal setiap tahunnya karena diare di seluruh dunia. Tujuan dari penelitian ini adalah mengevaluasi penggunaan antibiotik secara kuantitatif dan kualitatif. Penelitian ini merupakan penelitian prospektif ya…
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- vii, 110 hlm.; ilus.; 29 cm
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- T1421262024
UJI ANTINEFROLITHIASIS FRAKSI ETIL ASETAT DAUN MELINJO (Gnetum gnemon L.) TER…
The flavonoid content in melinjo leaves (Gnetum gnemon L.) has the potential to dissolve kidney stones through increased urinary citrate excretion, diuresis, and antioxidant effects. This study aims to examine the kidney stone dissolving activity of ethyl acetate fraction of melinjo leaves (FEADM) through urine pH, serum creatinine, ureum and kidney calcium levels, macroscopic and histopatholog…
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- xviii, 142 hlm.; ilus.; 29 cm
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- T1446942024
UJI AKTIVITAS ANTIDIABETES KULIT BUAH PISANG KEPOK (MUSA BALBISIANA COLLA) TE…
Kepok banana peel (Musa balbisiana Colla) is known to contain flavonoid secondary metabolites which have antidiabetic effects. The purpose of this research was to determine the effectiveness of reducing blood glucose levels in the ethanol fraction of Kepok banana peel. This study was divided into 6 groups, namely the normal group (0.5% Na-CMC suspension), positive control (Metformin 9mg/200g), …
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- xvii, 89 hlm.; ilus.; 29 cm
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- T1452652024
PREPARASI DAN KARAKTERISASI GEL PEMBAWA DISPERSI PADAT ERITROMISIN-PEG 6000 D…
Erythromycin has the properties of a macrolide derivative antibiotic, but erythromycin has the disadvantage that it is not soluble in water. One way to increase the solubility of erythromycin is through a solid dispersion system. The solid dispersion that has been made is then formulated into a gel preparation with the aim of inserting erythromycin through the skin pores. The gel base used is H…
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- xvii, 71 hlm.; ilus.; 29 cm
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- T1458222024
PENINGKATAN KELARUTAN DAN STABILITAS NANOPARTIKEL GELASI IONIK DENGAN EKSTRAK…
This research aims to increase the solubility of seaweed extract (sargassum sp) in sunscreen formulations using ionic gelation nanoparticles. determine the resulting characteristics including particle diameter, PDI, and zeta potential. This research begins with the seaweed process to make alginate, make ionic gelation nanoparticles and make sunscreen cream preparations. The ionic gelation metho…
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- xvi, 55 hlm.; ilus.; 29 cm
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- T1427802024
FORMULASI SUNSCREEN MENGGUNAKAN EKSTRAK RUMPUT LAUT (SARGASSUM. SP) DENGAN PE…
Sunscreen memiliki manfaat bagi kulit manusia yaitu melindung kulit dari paparan sinar matahari dimana vitamin D yang dibutuhkan oleh manusia dan bersumber dari sinar matahari tetapi akibat penipisan lapisan ozon, sinar matahari yang berbahaya menembus ke kulit manusia yang berdampak negatif jika terpapar terlalu lama. Penelitian ini dilakukan untuk mengetahui peningkatan stabilitas dan penetra…
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- xiv, 79 hlm.; ilus.; 29 cm
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- T1424592024
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