The high incidence of Out-of-Hospital Cardiac Arrest (OHCA) highlights the critical role of the community as bystanders. However, the assistance provided to victims remains suboptimal, leading to an increasing prevalence of OHCA-related mortality each year. This issue is primarily attributed to the public's limited knowledge of performing cardiopulmonary resuscitation (CPR), underscoring the ne…
Background: Cardiomegaly refers to an abnormal enlargement of the heart, which can be detected through various diagnostic methods, with echocardiography regarded as the gold standard. However, in patients who are bedridden, along with the limitations in healthcare infrastructure at some medical facilities, antero-posterior (AP) chest radiography serves as a more accessible alternative. This stu…
Medical students often face heavy academic burdens, high expectations for achievement, and difficulties in balancing studies with personal life. These conditions make them vulnerable to experiencing emotional mental disorders. However, awareness and intention to seek psychological help remain low. Seeking psychological help is an active effort to obtain support or treatment related to mental he…
Background: According to data released by the World Health Organization (WHO) in 2022, around 450,000 cases of TB-RO will occur throughout the world. In TB-RO patients there was an increase in the number of neutrophils and a decrease in the number of leukocytes. RNL calculations are carried out as an indicator that plays a role in reflecting the body's inflammatory response to infection. At the…
Background: Breast Milk is an essential source of nutrition for infants, containing micronutrients, macronutrients, and bioactive components that support their health and development. Breast milk consists of 87%-88% water, 7% lactose, 1% protein, and 3.8% fat, as well as various vitamins and antibodies that play a role in protecting infants from diseases. The composition of breast milk is influ…
Background: Hepatoma, or hepatocellular carcinoma, is the primary liver tumor accounting for 90% of liver tumor cases. In certain cases, hepatoma patients only undergo laboratory examinations without radiological imaging. An alternative method is needed to monitor tumor progression, predict patient prognosis, and determine appropriate treatment without radiological examinations, namely by measu…
Background: The most common superficial fungal skin disease, which has become a global health problem, is Tinea versicolor or Pityriasis versicolor. Personal hygiene behaviors were performed to maintain personal cleanliness and health. Several behaviors increased the risk of Pityriasis versicolor among scavengers, including not showering immediately after work, rarely changing work clothes, and…
Menopause is the cessation of menstruation for 12 consecutive months due to the loss of ovarian follicle function. Various factors can influence the menopausal process, such as dietary patterns, sleep patterns, stress levels, and physical activity. A study conducted by Mirrah in Palembang in 2023 revealed that 93.93% of women experienced menopausal symptoms. However, research on the relationshi…
Bakteri Klebsiella penumoniae dapat menyebabkan infeksi serius, terutama ketika sudah menyebar pada organ tubuh. Penggunaan antibiotik sering menjadi pilihan dalam menangani infeksi, namun bakteri dapat beradaptasi dengan membentuk biofilm. Senyawa antibiofilm yang biasa digunakan berbahan sintetik kimia yang dapat berdapak negatif pada manusia. Oleh karena itu, pencarian alternatif antibiofilm…
Background. Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia, requiring rational pharmacological therapy. Metformin is the first-line therapy for type 2 DM as recommended by WHO and the National Formulary. Defined Daily Dose (DDD) measurement enables a quantitative evaluation of drug use. However, studies on DDD for metformin in South Sumatra remain limited.…
Cervical cancer is the main cause of cancer death among woman and the third most cancer case in the world. High expression of VEGF in cervical cancer is linked to a poor prognosis, therefore anti-VEGF therapy has an important role in cervical cancer resolution. Several studies show that emodin inhibit proliferation, migration, and a formation of endothelial cells stimulated by VEGF. This resear…
Infectious diseases are a major health problem in Indonesia, with antibiotics being the primary choice for treatment. However, inappropriate antibiotic use can lead to resistance, increasing morbidity, mortality, and healthcare costs. The World Health Organization (WHO) recommends the Defined Daily Dose (DDD) method to standardize and measure antibiotic use for effective monitoring. This study …
Caffeine is commonly consumed to enhance alertness, combat drowsiness, reduce fatigue, and improve physical performance, such as increasing stamina and energy. Excessive consumption, however, may disrupt hormonal balance and sleep patterns, potentially affecting the menstrual cycle in women. This study aimed to investigate the relationship between coffee consumption and the menstrual cycle amon…
Introduction: Stroke is one of the leading causes of morbidity and mortality worldwide, including in Indonesia. Stroke can be categorized into two main types: ischemic stroke and hemorrhagic stroke, each influenced by various risk factors such as age, gender, history of hypertension, and cardiomegaly. This study aims to analyze the association between age, gender, history of hypertension, and c…
The global increase in life expectancy, including in Indonesia, has led to a growing elderly population, often accompanied by cognitive decline. This study aims to evaluate the effectiveness of a modified Brain Gym intervention in improving cognitive function among elderly residents of nursing homes. The study utilized a non-randomized experimental design with a pretest-posttest and control gro…
Malnutrition during pregnancy may affect the future health of both mother and child. Malnutrition occurs when the body has an excess or deficiency of nutrients. Diet is a factor that can be modified to achieve optimal pregnancy weight gain. This study aims to determine the association between maternal diet quality index and gestational weight gain. This study has an observational analytic desig…
Sepsis is one of the leading causes of acute kidney injury (AKI). Ureum and creatinine testing is a routine diagnostic tool for acute kidney failure. This study aimed to analyze differences in ureum and creatinine levels across AKI stages in sepsis patients.This study is an analytic descriptive study using a cross sectional study design. Data were collected from the medical records of AKI sepsi…
Cervical cancer is a malignancy of the cervix wall with a high prevalence among women worldwide, ranking third after breast and colorectal cancer. The disease is primarily caused by Human Papillomavirus (HPV) infection, with HPV types 16 and 18 being the leading cause in more than 70% of cases. Cervical cancer patient survival is influenced by various factors, including stage, histopathology ty…
Background: Diabetic ulcers are a serious complication of diabetes that commonly occur, especially in patients with poor glycemic control, neuropathy, and vascular disease. The Ankle-Brachial Index (ABI) is a non-invasive method used to assess the severity of ulcers. This study aims to analyze the relationship between ABI and the severity of diabetic ulcers in type 2 diabetes mellitus patients …
According to WHO, stunting is a condition where the TB/U Z-score is less than -2 SD. The problem that arises when children reach the age of 2 years is a critical period for growth disorders, including short stature or dwarfism. Genetic factors become the main foundation in achieving the final result of the child's growth and development process. The study untilized an analytic observational des…
Osteoarthritis (OA) is a degenerative joint disease of the joints characterized by cartilage destruction and thickening of the subchondral bone. Joint degeneration in osteoarthritis causes pain and stiffness, which limits joint movement. In Indonesia, the prevalence of osteoarthritis reaches 5% at age 61 years. Body mass index and physical activity are factors that can affect the severity of ge…
Pediatric transfusion-dependent thalassemia patients require lifelong transfusion to compensate for inadequate erythrocyte and to support patient’s growth and development. However, regular transfusion can cause iron overload leading to oxidative stress-induced liver injury. The purpose of this study is to analyze the relationship between iron overload and liver function in pediatric transfusi…
Hirschsprung disease (HSCR) is a congenital disorder of the large intestine resulting from missing nerve cells in the colon, leading to bowel obstruction. Despite surgical interventions, post-operative challenges, including constipation, incontinence, and emotional stress, can impact patients' quality of life. This study aims to evaluate the quality of life in school-aged HSCR patients post-sur…
Obesity in Indonesia has experienced a very significant increase over the past decade (10 years), especially in Palembang City. This rise can be influenced by several factors, one being behavioral factors. Poor eating habits and low physical activity contribute to the rising incidence of obesity in Palembang City. The purpose of this research is to analyze the significance of the relationship b…
Hipertensi adalah keadaan seseorang yang mengalami kenaikan tekanan darah diatas normal yaitu sistolik dan diastolik diatas 140/90 mmHg. Dalam proses terapinya, JNC8, AHA/ACC dan ESC menerbitkan pedoman terapi hipertensi dan merekomendasikan terapi lini pertama antara lain golongan ACEI, CCB, ARB dan obat diuretik golongan thiazid. Penelitian ini bertujuan untuk melihat penggunaan obat menurut …
Musculoskeletal disorders are injuries or functional impairments that result in abnormalities of the muscles, nerves, tendons, joints, cartilage, and spinal discs, leading to complaints of musculoskeletal pain. The Global Burden of Disease (GBD) 2019 data shows around 1.71 billion people of all ages experience musculoskeletal pain complaints throughout their lives. Ergonomic factors that cause …
Gastroesophageal Reflux Disease (GERD) is a common digestive disorder that affects quality of life, including sleep quality. GERD symptoms, especially those occurring at night, can lead to significant sleep disturbances, such as insomnia, frequent nighttime awakenings, and poor sleep quality. This condition can negatively impact daily life, particularly for students who bear a heavy academic wo…
One of the global health problems that is still neglected, especially in tropical and sub-tropical countries such as Indonesia, is soil-transmitted helminths (STH) infection. Scavengers who come into contact with the soil while working are a group that is vulnerable to STH contamination of the fingernails. This study aims to analyze the relationship between the level of personal hygiene and STH…
Background:Candy is a high-calorie food product, typically made with added sucrose, and if consumed excessively, it can lead to a decrease in saliva pH. A decrease in saliva pH causes the oral cavity to become acidic, facilitating the growth of bacteria, which in turn triggers cavities. To prevent a decrease in saliva pH, gambir extract is added to the candy. Gambir (Uncaria gambir Roxb.) is a …
Acute Otitis Media (AOM) is a condition characterized by inflammation of the middle ear mucosa, the Eustachian tube, antrum antrum, and mastoid cells, caused by bacteria or viruses. AOM is marked by the presence of fluid and/or inflammation in the middle ear. If a persistent perforation occurs with continuous discharge, it can lead to further complications, such as chronic suppurative otitis me…