UJI AKTIVITAS PENYEMBUHAN LUKA TERBUKA FRAKSI ETIL ASETAT DAUN SINGKONG (Mani…

National injury prevalence tends to increase every year. Wounds must be healed immediately because they are an important role in maintaining homeostasis and have the potential to become chronic infections if not treated. Cassava leaves (Manihot esculenta) contain the main substance rutin or quercetin 3-O-rutinoside (flavonoids) and contain saponins and tannins as anti-inflammatory, antibacteria…

UJI ANTINEFROLITHIASIS FRAKSI ETANOL DAUN KERSEN (Muntingia calabura L.) TERH…

Kidney stone disease (antinefrolithiasis) of calcium stone type is one of the health problems among Indonesian people. The use of diuretic drugs as a treatment for kidney stones can be replaced with natural ingredients to reduce the risk of side effects. Kersen leaves (Muntingia calabura L.) contain a lot of flavanes, flavones, flavanones, flavonols, and chalcones which are included in the flav…

UJI ANTINEFROLITHIASIS FRAKSI ETIL ASETAT DAUN KERSEN (Muntingia calabura L.)…

Kidney stone disease (antinefrolithiasis) of calcium stone type is one of the health problems among Indonesian people. The use of diuretic drugs as a treatment for kidney stones can be replaced with natural ingredients to reduce the risk of side effects. Kersen leaves (Muntingia calabura L.) contain a lot of flavanes, flavones, flavanones, flavonols, and chalcones which are included in the flav…

FORMULASI DAN UJI ANTIOKSIDAN ORALLY DISSOLVING FILM EKSTRAK ETANOL BUNGA KEC…

Kecombrang flower (Etlingera elatior) contains various secondary metabolite compounds, one of which is flavonoids that have antioxidant activity. Orally Dissolving Film (ODF) was formulated to cover the unpleasant taste of kecombrang flowers. Pullulan is used as a polymer due to its ease of solubility in water and has good film-forming properties. This study aims to determine the best formulati…

FORMULASI NANOPARTIKEL PERAK-MAGNETIT MENGGUNAKAN METODE GREEN SYNTHESIS DENG…

Thrombosis is a condition in which a blood clot (thrombus) forms in a blood vessel. Treatment involves antithrombotic agents such as anticoagulants, and researchers developed silver-magnetite nanoparticles (Ag-Fe₃O₄) using a green synthesis method using robusta coffee bean extract (Coffea canephora) containing chlorogenic acid as a natural reducing, stabilizing, and thrombolytic agent. The …

GREEN SYNTHESIS NANOPARTIKEL BESI OKSIDA EKSTRAK JARAH GAMBIR (UNCARIA GAMBIR…

Thrombosis is a leading global cause of cardiovascular diseases. While anticoagulants, antiplatelet agents, and thrombolytic therapies are the standard clinical treatments, iron oxide nanoparticles offer an alternative approach due to their ability to accumulate at sites of inflammation, such as thrombi and atherosclerotic plaques. These nanoparticles can act as photothermal agents, absorbing l…

KARAKTERISASI LIPOSOM PHOTOSENSITIZER PEMBAWA EKSTRAK KASAR NANAS (Ananas com…

Thrombosis is a condition that occurs due to an imbalance in the hemostasis system characterized by the formation of a blood clot (thrombus) in the blood vessel wall so that it can cause ischemic stroke disease. The anti-thrombotic drugs commonly used are thrombolytics. These drugs contain fibrinolytic enzymes such as protease enzymes. Pineapple (Ananas comosus (L.) Merr) is known to have an an…

OPTIMASI GREEN SYNTHESIS NANOPARTIKEL Ag-Fe3O4 MENGGUNAKAN EKSTRAK AIR BUNGA …

Thrombosis caused by blood clot formation can lead to serious complications. Conventional therapies carry a risk of bleeding, making photothermal therapy based on optical-magnetic nanoparticles such as AgNO₃ and Fe₃O₄ a safer alternative. These nanoparticles are synthesized via green synthesis using butterfly pea flower (Clitoria ternatea L.) extract, which contains flavonoids and anthocy…

FORMULASI DAN UJI ANTIOKSIDAN ORALLY DISSOLVING FILM EKSTRAK ETANOL BUNGA KEC…

Kecombrang flower (Etlingera elatior) are plant from the Zingiberaceae family which has potential as an antioxidant. Kecombrang flowers have a distinctive smell and sour taste. The orally dissolving film (ODF) formulation which uses a combination of HPMC polymer and maltodextrin was able to eliminate the unpleasant taste of kecombrang flowers. Orally dissolving film (ODF) preparations was made …

EFEK TERATOGENIK FRAKSI ETIL ASETAT DAUN MELINJO (Gnetum gnemon L.) PADA FETU…

One of the special toxicity tests is the teratogenic test which is carried out to obtain information on the presence of fetal abnormalities that occur due to the administration of test preparations during the formation of fetal organs (organogenesis period) and to complete safety data from the melinjo plant. The doses given were 69.48, 104.22, 138.96 and 173.7 mg/kgBW. The administration of the…

EFEK TERATOGENIK FRAKSI ETANOL DAUN KERSEN (Muntingia calabura L.) PADA FETUS…

Kersen leaves (Muntingia Calabura L) contain secondary metabolite compounds alkaloids, flavonoids and tanins. The use of herbal medicine during pregnancy needs to be considered because the drug can cross the placenta so that it can cause teratogenic effects on the fetus. Teratogenic toxicity research on the ethanol fraction of kersen leaves (Muntingia Calabura L) has been conducted to determine…

UJI AKTIVITAS ANTIDIABETES FRAKSI ETIL ASETAT KULIT BUAH PISANG KEPOK (MUSA B…

ABSTRAK Kulit pisang kepok, yang mengandung sejumlah senyawa metabolit sekunder seperti flavonoid, telah diketahui memiliki potensi sebagai agen antidiabetes. Penelitian ini bertujuan untuk mengevaluasi seberapa efektif fraksi etil asetat dari kulit pisang kepok dalam menurunkan kadar glukosa darah. Penelitian melibatkan pembagian tikus percobaan ke dalam enam kelompok: kelompok normal (mendapa…

EVALUASI PENGGUNAAN ANTIBIOTIK PADA PASIEN DEMAM TIFOID DENGAN METODE ATC/DDD…

Typhoid fever is an acute infectious disease of the small intestine caused by food and drinks contaminated with Salmonella typhi bacteria. The purpose of this study was to determine the profile of antibiotic drug use in typhoid fever patients, to determine the quantitative evaluation and qualitative evaluation of antibiotic use. This study is a descriptive study conducted retrospectively, the d…

ANALISIS HUBUNGAN KEPATUHAN PENGGUNAAN OBAT TERHADAP KUALITAS HIDUP PASIEN GA…

Hemodialysis is the primary treatment for patients with Chronic Kidney Failure (CKD). CKD Patients experience disruptions in fluid balance, electrolyte levels, acid-base balance, hormone production, and the secretion of toxic metabolic waste. This study aims to analyze the relationship between adherence to medication use and the quality of life of CKD patients with hemodialysis therapy at RSI S…

ANALISIS HUBUNGAN PENGGUNAAN OBAT PENURUN KADAR KOLESTEROL TERHADAP KUALITAS …

Pengobatan yang baik berpengaruh pada tingkat pengetahuan, kepatuhan minum obat penurun kadar kolesterol dan kualitas hidup pasien. Tujuan penelitian ini adalah menganalisis hubungan antara tingkat kepatuhan minum obat dengan kualitas hidup pasien hiperkolesterolemia di Rumah Sakit Islam Siti Khadijah Palembang. Desain penelitian dilakukan secara observasional analitik dengan pendekatan cross-s…

EFEK PREVENTIF FRAKSI ETIL ASETAT DAUN MELINJO (Gnetum gnemon L.) SEBAGAI HEP…

Melinjo leaves (Gnetum gnemon L.) is a plan that is often used as a medicinal ingredient because it has a high content of secondary metabolites. Secondary metabolites that are thought to act as hepatoprotectors are flavonoid. This study aims to determine the decrease in SGPT and SGOT levels of various doses, determine ED50 (Effective Dose 50) and determine the effect on the macroscopic and hist…

STANDARISASI DAN UJI TOKSISITAS AKUT EKSTRAK ETANOL RIMPANG TEMU MANGGA (Curc…

Temu mango rhizome (Curcuma amada Roxb.) is one of the plants that has anti-inflammatory and antidiabetic activities. The safety of using temu mango rhizome as a natural medicinal preparation must be supported by scientific research on toxicity testing. This study aims to evaluate the characteristics of acute toxicity of ethanol extract of temu mango rhizome to female Wistar rats using the Acut…

UJI HEPATOPROTEKTOR FRAKSI ETIL ASETAT DAUN MELINJO (Gnetum gnemon L.) DAN GA…

Melinjo leaves (Gnetum gnemon L.) have benefits in the field of traditional medicine. Melinjo leaves (Gnetum gnemon L.) contain secondary metabolite compounds such as flavonoids, saponins, tannins, phenolics, and saponins. This study aims to determine the hepatoprotector activity of ethyl acetate fraction of melinjo leaves (Gnetum gnemon L.) and hepatic histopathological picture of male white r…

Kimia Farmasi Analisis

Edition

-

ISBN/ISSN

978-623-180-167-8

Collation

vii, 118 hlm.; ilus., tab., 24 cm

Series Title

-

Call Number

615.1 Was k

ANALISA PERBANDINGAN RETURN DAN RISK SAHAM PERUSAHAAN INDUSTRI ROKOK DAN INDU…

Edition

-

ISBN/ISSN

-

Collation

xiv, 108 hlm.: Ilus., tab.; 28 cm

Series Title

-

Call Number

T591522005

DEFINED DAILY DOSE PENGGUNAAN OBAT ANTIHIPERTENSI DI PUSKESMAS MERDEKA PALEMBANG

Hipertensi adalah keadaan seseorang yang mengalami kenaikan tekanan darah diatas normal yaitu sistolik dan diastolik diatas 140/90 mmHg. Dalam proses terapinya, JNC8, AHA/ACC dan ESC menerbitkan pedoman terapi hipertensi dan merekomendasikan terapi lini pertama antara lain golongan ACEI, CCB, ARB dan obat diuretik golongan thiazid. Penelitian ini bertujuan untuk melihat penggunaan obat menurut …

FORMULASI DAN EVALUASI SEDIAAN ACNE PATCH TRANSDERMAL EKSTRAK ETANOL DAUN CAB…

Acne is a condition characterized by the accumulation of sebum from sebaceous glands in the skin layers, which often stimulates the growth of acne-causing bacteria, such as Staphylococcus aureus. Acne treatment can be performed using acne patches; however, commercial acne patches are only capable of absorbing sebum without providing antibacterial activity. This study aimed to enhance therapeuti…

STANDARDISASI DAN UJI TOKSISITAS AKUT EKSTRAK ETANOL RIMPANG TEMU IRENG (Curc…

Temu ireng (Curcuma aeruginosa Roxb.) is one of the medicinal plants that has been reported to have antioxidant, antibacterial, anti-inflammatory, and hepatoprotector activities, but this plant has not been widely studied regarding its toxicity. This study conducted an acute toxicity test of ethanol extract of temu ireng rhizome against female Wistar strain rats using the Acute Toxic Class meth…

 FORMULASI DAN UJI ANTIOKSIDAN ORALLY DISSOLVING FILM EKSTRAK ETANOL BUNGA K…

Bunga kecombrang (Etlingera elatior) dikenal sebagai bunga khas Asia tenggara famili Zingiberaceae dengan warna merah menyala dan bau khas. Pemanfaatan sediaan orally dissolving film (ODF) dapat menetralisir rasa asam pada bunga kecombrang. Variasi konsentrasi ekstrak etanol bunga kecombrang 0,5%, 0,6%, 0,7%. Evalusi sediaan untuk menentukan formula terbaik meliputi organoleptis, ketebalan, bob…

ISOLASI MINYAK ATSIRI PADA TANAMAN GAMBIR (Uncaria gambir Roxb) DAN INDETIFIK…

Essential oil is one of the non-oil and gas export commodities, gambir is one of the sap-producing plants used for industrial and pharmaceutical purposes, how much gambir essential oil and yield obtained and what components are contained in gambir essential oil, and how much yield is obtained, knowing the components contained in gambir essential oil (Uncaria Gambir Roxb), the research method us…

ANALISIS DRUG RELATED PROBLEMS (DRPs) PADA PASIEN HIPERLIPIDEMIA DENGAN KOMPL…

Hyperlipidemia is a metabolic disorder that acts as a major risk factor for cardiovascular disease. This condition is often accompanied by various complications such as hypertension, diabetes mellitus, and ischemic heart disease, which causes higher complexity of therapy. The complexity of treatment in hyperlipidemia patients increases the potential for Drug-Related Problems (DRPs), which can a…

UJI STIMULASI PROBIOTIK Bifidobacterium longum DENGAN EKSTRAK ETANOL DAUN PUT…

This study aims to evaluate the potential of ethanol extract of putat leaves (Barringtonia acutangula) in stimulating the growth of probiotic Bifidobacterium longum and test its ability to inhibit the growth of pathogenic Escherichia coli bacteria. Bifidobacterium longum is one of the lactic acid bacteria that are beneficial for human gut health, while E. coli bacteria are known as opportunisti…

FORMULASI SEDIAAN SPANSULE EKSTRAK ETANOL DAUN PUTAT (Barringtonia acutangula…

Diarrhea caused by Escherichia coli infections remains a significant public health problem in developing countries, including Indonesia. Overuse of antibiotics can lead to resistance, so alternatives are needed. Putat leaves (Barringtonia acutangula) contain the flavonoid quercetin, which has prebiotic and antibacterial potential. This study aims to investigate the effect of putat leaf extract …

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAN FRAKSI HERBA SIRIH CINA (peperomia pell…

Chinese betel leaf (peperomia pellucida) contains secondary metabolite compounds such as flavonoids and terpenoids that have potential as antioxidants. This study aims to determine the effect of giving extracts and fractions of Chinese betel herb invivo on male Wistar rats induced oxidative stress by carbon tetrachloride (CCl4). The 30 test animals were divided into 6 treatment groups, namely t…

UJI AKTIVITAS ANTIDEPRESAN EKSTRAK ETANOL DAUN AKASIA (acacia mangim wild) TE…

Acacia leaves (Acacia Mangium Wild) contain secondary metabolite compounds of flavonoids in the form of quercetin which have the potential as antidepressants. This study aims to determine the effect of giving ethanol extract of acacia leaves and its effective dose on antidepressant activity. This study used 30 test animals which were divided into 6 groups, namely, the normal group (1 NaCMC with…