Osteoarthritis (OA) merupakan bentuk penyakit sendi yang paling umum ditemukan di dunia dan diasosiasikan oleh usia. OA bermula saat faktor katabolik, sepeti TNF-α, yang berperan pada metabolisme kartilago mendominasi dan menekan faktor anabolik membuat degradasi kartilago terjadi. Faktor pertumbuhan yang didapat dari platelet memiliki peran krusial dalam penyembuhan jaringan dan respons imun.…
Osteoarthritis (OA) adalah gangguan sendi yang paling umum dan merupakan penyebab utama disabilitas dengan dampak sosial ekonomi yang besar dan terjadi akibat ketidakseimbangan mediator proinflamasi dan antiinflamasi atau aktivitas anabolik dan katabolik. Penelitian ini bertujuan untuk mengetahui pengaruh Faktor Pertumbuhan Platelet (FPP) terhadap kadar Alpha-SMA. Penelitian ini merupakan studi…
In this paper, we concentrate on a stochastic non-monotone DR-submodular maximization problem over a convex constraint , where the objective function arises as an expectation of a set of stochastic functions. We develop an algorithm named SPIDER-FW, which is a stochastic version of the classical Frank-Wolfe algorithm with (in expectation) approximation guarantee, the best guarantee so far …
Comprehension learners sometimes have a different understanding of concepts than scientifically accepted concepts, leading to misconceptions. The purpose of this study was to determine the validity and reliability of three tier diagnostic tests of human reproductive system material in high school students in Muara Enim Regency. The method in this study is the Treagust development method which i…
Background: Stem of yellow wood (Arcangelisia flava) is a plant that are efficacious as an antihyperuricemic. This is because it contains secondary metabolites in the form of alkaloids, flavonoids, terpenoids, and tannins. Previous research conducted in vitro research on ethyl acetate extract from stem of the yellow wood (Arcangelisia flava) which has been proven to be antihyperuricemic. This s…
Background. Critical illness is a life threatening disease, therefore intensive care and comprehensive observation are required. Intensive care in hospital is mandatory which requires attention to the assessment of the patient's nutritional status. Malnutrition can occur when a child is admitted to the hospital and can get worse while the child is on an undergoing treatment in hospital. Malnutr…
Osteoarthritis (OA) adalah penyakit degeneratif tulang rawan sendi yang diikuti oleh peradangan rongga synovial. Interleukin-1β (IL-1β) bertanggung jawab pada proses terjadi OA. Faktor pertumbuhan platelet diprediksi mampu memodulasi penyembuhan OA. Tujuan penelitian ini untuk mengetahui pengaruh pemberian FPP terhadap kadar IL-1β. Eksperimental in vivo menggunakan pendekatan post-test only …
Background. Human immunodeficiency virus (HIV) infection is one of the risk factors for the development of TB cases. Co-infection with TB and HIV is a serious problem with high rates of cases globally and in Indonesia, which, if not properly managed, can pose a threat to public health. Information on age, gender, and laboratory results, including hemoglobin levels and CD4 cell counts, are neede…