EFEK TERATOGENIK FRAKSI ETIL ASETAT DAUN MELINJO (Gnetum gnemon L.) PADA FETU…

One of the special toxicity tests is the teratogenic test which is carried out to obtain information on the presence of fetal abnormalities that occur due to the administration of test preparations during the formation of fetal organs (organogenesis period) and to complete safety data from the melinjo plant. The doses given were 69.48, 104.22, 138.96 and 173.7 mg/kgBW. The administration of the…

EFEK TERATOGENIK FRAKSI ETANOL DAUN KERSEN (Muntingia calabura L.) PADA FETUS…

Kersen leaves (Muntingia Calabura L) contain secondary metabolite compounds alkaloids, flavonoids and tanins. The use of herbal medicine during pregnancy needs to be considered because the drug can cross the placenta so that it can cause teratogenic effects on the fetus. Teratogenic toxicity research on the ethanol fraction of kersen leaves (Muntingia Calabura L) has been conducted to determine…

UJI AKTIVITAS ANTIDIABETES FRAKSI ETIL ASETAT KULIT BUAH PISANG KEPOK (MUSA B…

ABSTRAK Kulit pisang kepok, yang mengandung sejumlah senyawa metabolit sekunder seperti flavonoid, telah diketahui memiliki potensi sebagai agen antidiabetes. Penelitian ini bertujuan untuk mengevaluasi seberapa efektif fraksi etil asetat dari kulit pisang kepok dalam menurunkan kadar glukosa darah. Penelitian melibatkan pembagian tikus percobaan ke dalam enam kelompok: kelompok normal (mendapa…

EVALUASI PENGGUNAAN ANTIBIOTIK PADA PASIEN DEMAM TIFOID DENGAN METODE ATC/DDD…

Typhoid fever is an acute infectious disease of the small intestine caused by food and drinks contaminated with Salmonella typhi bacteria. The purpose of this study was to determine the profile of antibiotic drug use in typhoid fever patients, to determine the quantitative evaluation and qualitative evaluation of antibiotic use. This study is a descriptive study conducted retrospectively, the d…

ANALISIS HUBUNGAN KEPATUHAN PENGGUNAAN OBAT TERHADAP KUALITAS HIDUP PASIEN GA…

Hemodialysis is the primary treatment for patients with Chronic Kidney Failure (CKD). CKD Patients experience disruptions in fluid balance, electrolyte levels, acid-base balance, hormone production, and the secretion of toxic metabolic waste. This study aims to analyze the relationship between adherence to medication use and the quality of life of CKD patients with hemodialysis therapy at RSI S…

ANALISIS HUBUNGAN PENGGUNAAN OBAT PENURUN KADAR KOLESTEROL TERHADAP KUALITAS …

Pengobatan yang baik berpengaruh pada tingkat pengetahuan, kepatuhan minum obat penurun kadar kolesterol dan kualitas hidup pasien. Tujuan penelitian ini adalah menganalisis hubungan antara tingkat kepatuhan minum obat dengan kualitas hidup pasien hiperkolesterolemia di Rumah Sakit Islam Siti Khadijah Palembang. Desain penelitian dilakukan secara observasional analitik dengan pendekatan cross-s…

EFEK PREVENTIF FRAKSI ETIL ASETAT DAUN MELINJO (Gnetum gnemon L.) SEBAGAI HEP…

Melinjo leaves (Gnetum gnemon L.) is a plan that is often used as a medicinal ingredient because it has a high content of secondary metabolites. Secondary metabolites that are thought to act as hepatoprotectors are flavonoid. This study aims to determine the decrease in SGPT and SGOT levels of various doses, determine ED50 (Effective Dose 50) and determine the effect on the macroscopic and hist…

STANDARISASI DAN UJI TOKSISITAS AKUT EKSTRAK ETANOL RIMPANG TEMU MANGGA (Curc…

Temu mango rhizome (Curcuma amada Roxb.) is one of the plants that has anti-inflammatory and antidiabetic activities. The safety of using temu mango rhizome as a natural medicinal preparation must be supported by scientific research on toxicity testing. This study aims to evaluate the characteristics of acute toxicity of ethanol extract of temu mango rhizome to female Wistar rats using the Acut…

UJI HEPATOPROTEKTOR FRAKSI ETIL ASETAT DAUN MELINJO (Gnetum gnemon L.) DAN GA…

Melinjo leaves (Gnetum gnemon L.) have benefits in the field of traditional medicine. Melinjo leaves (Gnetum gnemon L.) contain secondary metabolite compounds such as flavonoids, saponins, tannins, phenolics, and saponins. This study aims to determine the hepatoprotector activity of ethyl acetate fraction of melinjo leaves (Gnetum gnemon L.) and hepatic histopathological picture of male white r…

Kimia Farmasi Analisis

Edition

-

ISBN/ISSN

978-623-180-167-8

Collation

vii, 118 hlm.; ilus., tab., 24 cm

Series Title

-

Call Number

615.1 Was k

ANALISA PERBANDINGAN RETURN DAN RISK SAHAM PERUSAHAAN INDUSTRI ROKOK DAN INDU…

Edition

-

ISBN/ISSN

-

Collation

xiv, 108 hlm.: Ilus., tab.; 28 cm

Series Title

-

Call Number

T591522005

DEFINED DAILY DOSE PENGGUNAAN OBAT ANTIHIPERTENSI DI PUSKESMAS MERDEKA PALEMBANG

Hipertensi adalah keadaan seseorang yang mengalami kenaikan tekanan darah diatas normal yaitu sistolik dan diastolik diatas 140/90 mmHg. Dalam proses terapinya, JNC8, AHA/ACC dan ESC menerbitkan pedoman terapi hipertensi dan merekomendasikan terapi lini pertama antara lain golongan ACEI, CCB, ARB dan obat diuretik golongan thiazid. Penelitian ini bertujuan untuk melihat penggunaan obat menurut …

FORMULASI DAN EVALUASI SEDIAAN ACNE PATCH TRANSDERMAL EKSTRAK ETANOL DAUN CAB…

Acne is a condition characterized by the accumulation of sebum from sebaceous glands in the skin layers, which often stimulates the growth of acne-causing bacteria, such as Staphylococcus aureus. Acne treatment can be performed using acne patches; however, commercial acne patches are only capable of absorbing sebum without providing antibacterial activity. This study aimed to enhance therapeuti…

STANDARDISASI DAN UJI TOKSISITAS AKUT EKSTRAK ETANOL RIMPANG TEMU IRENG (Curc…

Temu ireng (Curcuma aeruginosa Roxb.) is one of the medicinal plants that has been reported to have antioxidant, antibacterial, anti-inflammatory, and hepatoprotector activities, but this plant has not been widely studied regarding its toxicity. This study conducted an acute toxicity test of ethanol extract of temu ireng rhizome against female Wistar strain rats using the Acute Toxic Class meth…

 FORMULASI DAN UJI ANTIOKSIDAN ORALLY DISSOLVING FILM EKSTRAK ETANOL BUNGA K…

Bunga kecombrang (Etlingera elatior) dikenal sebagai bunga khas Asia tenggara famili Zingiberaceae dengan warna merah menyala dan bau khas. Pemanfaatan sediaan orally dissolving film (ODF) dapat menetralisir rasa asam pada bunga kecombrang. Variasi konsentrasi ekstrak etanol bunga kecombrang 0,5%, 0,6%, 0,7%. Evalusi sediaan untuk menentukan formula terbaik meliputi organoleptis, ketebalan, bob…

ISOLASI MINYAK ATSIRI PADA TANAMAN GAMBIR (Uncaria gambir Roxb) DAN INDETIFIK…

Essential oil is one of the non-oil and gas export commodities, gambir is one of the sap-producing plants used for industrial and pharmaceutical purposes, how much gambir essential oil and yield obtained and what components are contained in gambir essential oil, and how much yield is obtained, knowing the components contained in gambir essential oil (Uncaria Gambir Roxb), the research method us…

ANALISIS DRUG RELATED PROBLEMS (DRPs) PADA PASIEN HIPERLIPIDEMIA DENGAN KOMPL…

Hyperlipidemia is a metabolic disorder that acts as a major risk factor for cardiovascular disease. This condition is often accompanied by various complications such as hypertension, diabetes mellitus, and ischemic heart disease, which causes higher complexity of therapy. The complexity of treatment in hyperlipidemia patients increases the potential for Drug-Related Problems (DRPs), which can a…

UJI STIMULASI PROBIOTIK Bifidobacterium longum DENGAN EKSTRAK ETANOL DAUN PUT…

This study aims to evaluate the potential of ethanol extract of putat leaves (Barringtonia acutangula) in stimulating the growth of probiotic Bifidobacterium longum and test its ability to inhibit the growth of pathogenic Escherichia coli bacteria. Bifidobacterium longum is one of the lactic acid bacteria that are beneficial for human gut health, while E. coli bacteria are known as opportunisti…

FORMULASI SEDIAAN SPANSULE EKSTRAK ETANOL DAUN PUTAT (Barringtonia acutangula…

Diarrhea caused by Escherichia coli infections remains a significant public health problem in developing countries, including Indonesia. Overuse of antibiotics can lead to resistance, so alternatives are needed. Putat leaves (Barringtonia acutangula) contain the flavonoid quercetin, which has prebiotic and antibacterial potential. This study aims to investigate the effect of putat leaf extract …

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAN FRAKSI HERBA SIRIH CINA (peperomia pell…

Chinese betel leaf (peperomia pellucida) contains secondary metabolite compounds such as flavonoids and terpenoids that have potential as antioxidants. This study aims to determine the effect of giving extracts and fractions of Chinese betel herb invivo on male Wistar rats induced oxidative stress by carbon tetrachloride (CCl4). The 30 test animals were divided into 6 treatment groups, namely t…

UJI AKTIVITAS ANTIDEPRESAN EKSTRAK ETANOL DAUN AKASIA (acacia mangim wild) TE…

Acacia leaves (Acacia Mangium Wild) contain secondary metabolite compounds of flavonoids in the form of quercetin which have the potential as antidepressants. This study aims to determine the effect of giving ethanol extract of acacia leaves and its effective dose on antidepressant activity. This study used 30 test animals which were divided into 6 groups, namely, the normal group (1 NaCMC with…

Nutrasetikal

Nutrasetikal adalah sejenis makanan yang memiliki manfaat untuk kesehatan secara medis, termasuk pencegahan dan pengobatan penyakit. Makanan seperti ini sering disebut functional foods, yang menandakan bahwa komponennya dapat memberikan manfaat untuk kesehatan, lebih dari sekedar nutrisi dasar, contohnya sayuran dan buah-buahan serta makanan yang telah diperkaya (portified). Dalam proses pengem…

EVALUASI PENGARUH WAKTU TUNGGU RESEP TERHADAP TINGKAT KEPUASAN PASIEN RAWAT J…

Pharmaceutical services are an important aspect of health facilities that directly affect patient satisfaction, one such service is prescription services. Patients often complain about waiting time for prescription services because it impacts their experience obtaining health services. The objective of this study evaluates how waiting time towards prescription services affects outpatient satisf…

STUDI IN SILICO EKSTRAK BUNGA KECOMBRANG (Etlingera Elatior) SEBAGAI ANTIBAKT…

Staphylococcus aureus infection is caused by a bacterium that colonizes various organs in the human body, particularly the upper respiratory tract, including the skin, nasal cavity, axilla, and inguinal area. The emergence of antibiotic-resistant S. aureus, known as MRSA and VRSA, presents a significant challenge in the treatment of such infections. Natural products, such as the torch ginger fl…

BIOSINTESIS NANOPARTIKEL EMAS BERBASIS EKSTRAK ETANOL KULIT BUAH SUKUN SEBAGA…

Thrombosis is caused by the formation of abnormal blood clots in arterial or venous vessels, which obstruct blood flow. Conventional thrombolytic therapies, such as streptokinase and alteplase, carry a high risk of systemic bleeding. As an alternative, thrombolytic therapy using gold nanoparticles synthesized with green synthesis approach utilizes breadfruit peel extract (Artocarpus altilis) as…

PREPARASI DAN KARAKTERISASI SUBMIKRO PARTIKEL KITOSAN-ALGINAT PEMBAWA CEFIXIM…

Cefixime is a broad-spectrum antibiotic with low water solubility, which limits its absorption in the gastrointestinal tract and affects its therapeutic effectiveness. To address this limitation, a submicroparticle formulation of chitosan-alginate loaded with cefixime was developed using the ionic gelation method with CaCl₂ as a cross-linker. This approach aims to enhance the solubility, stab…

LIPOSOM PHOTOTHERMAL SENSITIZER DENGAN ENZIM TEMPE BONGKREK SEBAGAI TERAPI TR…

Thrombosis can trigger diseases such as ischemic stroke and acute myocardial infarction. Thrombosis therapy is usually administered with antiplatelets, anticoagulants, and thrombolytic agents. Unlike antiplatelets and anticoagulants which are preventive, thrombolytic agents work directly to dissolve thrombus, for example tPA. Tempe bongkrek is a food fermented by Rhizopus oligosporus fungus tha…

PEMANFAATAN MINYAK ATSIRI NILAM SEBAGAI ANTIBAKTERI TERHADAP Staphylococcus a…

Excessive sweat production caused body odor to appear in certain parts of the body, one of which was Staphylococcus aureus. Deodorant lotion was applied to the armpit as a topical antibacterial preparation. Deodorant lotion was prepared with different concentrations of patchouli essential oil of 0%, 5%, 7%, and 10%. The deodorant lotion was tested for physical properties including organoleptic,…

STUDI DRUG RELATED PROBLEMS (DRPs) PADA PASIEN CHRONIC KIDNEY DISEASE (CKD) D…

Chronic Kidney Disease (CKD) is a condition of impaired kidney function that is influenced by clinical factors such as diabetes, hypertension, obesity, autoimmune, infection, or with other complications so that therapy involves polypharmacy. Polypharmacy therapy is thought to cause an increased risk of Drug Related Problems (DRPs). The purpose of this study was to analyze DRPs in CKD patients a…

PENGARUH KEPATUHAN DAN EDUKASI PASIEN HIPERTENSI TERHADAP PENURUNAN TEKANAN D…

Hypertension treatment must be accompanied by compliance with medication consumption and good blood pressure management, otherwise this condition can be a major cause of morbidity and mortality in various countries including Indonesia. Hypertension therapy is highly dependent on the level of patient compliance in undergoing treatment to maintaining blood pressure stability, increasing the effec…