Background: Nasopharyngeal non-Hodgkin lymphoma (NHL) is an extranodal lymphoid malignancy of the head and neck that is treated with systemic chemotherapy. Chemotherapy may be accompanied by changes in hematological parameters; therefore, monitoring of hematological profiles is required. Data regarding the hematological profile of patients with nasopharyngeal NHL in Indonesia are still limited.…
Meningioma is the most commonly diagnosed primary tumor of the central nervous system, with the majority being benign (WHO Grade I). Imaging modalities such as CT-Scan and MRI play a crucial role in the diagnosis and evaluation of meningioma. This study aims to describe the imaging features of brain scans in meningioma patients at Dr. Mohammad Hoesin General Hospital Palembang during the period…
Background: Drug allergy is a hypersensitivity reaction to medications involving immunological mechanisms that can cause clinical manifestations ranging from mild to severe, such as rash, urticaria, and anaphylaxis. Children are a vulnerable group due to their immature immune systems and limited alternative treatment options. This study aimed to determine the distribution of drug allergy incide…
Tuberculosis (TB) is an infectious disease that remains a major public health problem in Indonesia. TB transmission often occurs within households through close contact with infected individuals. This study aims to identify the risk factors associated with TB occurrence among household contacts of TB patients at Siti Fatimah Regional Hospital, South Sumatra. This research employed a descriptive…
Background: Wound healing is a complex biological process that progresses through the phases of inflammation, proliferation, and remodeling. Cung kediro (Solanum lycopersicum var. cerasiforme) contains lycopene, β–carotene, vitamin C, and flavonoids, which act as potent antioxidants and have the potential to accelerate epithelialization, angiogenesis, and keratinization. This study aimed to …
Background: Epidural hematoma (EDH) is defined as the accumulation of blood between the dura mater and the internal table due to trauma. Epidural hematoma occupies intracranial space, which can cause rapid expansion of bleeding. This causes pressure on the brain and triggers clinical manifestations such as decreased consciousness, reversible or irreversible disability, and even death. GCS is th…
Background. Systemic Lupus Erythematosus (SLE) is a chronic multisystem autoimmune disease characterized by the production of autoantibodies and excessive immune activation, resulting in widespread organ damage. Immunosuppressive therapy constitutes a cornerstone in the management of SLE by suppressing abnormal immune responses and preventing further organ injury. The effectiveness of such ther…
Background: Menstruation is a physiological process experienced by adolescent girls as a sign of reproductive maturity. Inadequate personal hygiene practices during menstruation can increase the risk of urinary tract and reproductive tract infections. Female students living in Islamic boarding schools face unique challenges, such as limited sanitation facilities, lack of privacy, and cultural f…
Introduction: Oxidative stress is an imbalance between free radicals and endogenous antioxidants that plays a role in the pathogenesis of various degenerative diseases. Natural antioxidants from plants, particularly those containing phenolic compounds and flavonoids, have become potential alternatives for the prevention of oxidative stress. Kersen mistletoe leaves contain various secondary meta…
Neck pain is one of the most common musculoskeletal complaints across various age groups, including elementary school-aged children, and may be influenced by postural factors such as Forward Head Posture (FHP). This study aimed to analyze the relationship between FHP and neck pain among elementary school students. An observational analytic study with a cross-sectional design was conducted invol…
Background: Obesity is a global health problem that contributes to metabolic disorders, one of which is through changes in the structure and function of the pancreas, particularly the islets of Langerhans. Intermittent fasting, especially time- restricted feeding, is known to have the potential to improve metabolic parameters and tissue structure, but its effect on histology and islet diameter …
Background: Low birth weight (LBW) is a condition in which an infant is born weighing less than 2,500 grams, regardless of gestational age. LBW is an important indicator of perinatal health because it can lead to both short-term and long-term complications, such as growth impairment, increased risk of chronic diseases, and neonatal mortality. The occurrence of LBW is multifactorial, influenced …
Background: β-thalassemia major is a genetic disorder that causes chronic anemia, requiring patients to undergo regular lifelong blood transfusions. Repeated transfusions and ineffective erythropoiesis lead to iron accumulation, which is indicated by elevated serum ferritin levels. Iron overload can affect endocrine function, including growth hormone, thereby increasing the risk of growth diso…
Background. Pelvic organ prolapse (POP) is one of the most common pelvic floor disorders affecting women. This condition is caused by weakening of the pelvic floor supportive structures, with risk factors including age, obesity, menopause, parity, vaginal delivery, and a history of pelvic surgery. This study aims to determine the incidence of POP at RSUD Siti Fatimah Palembang and to identify t…
Introduction : Low back pain (LBP) is a global health problem that significantly impacts quality of life. LBP can be classified as inflammatory or non-inflammatory. Recently, the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been studied as practical, accessible, and economical inflammatory biomarkers, potentially supporting evaluation of inflammatory processe…
Background: Systolic blood pressure (SBP) is presumed to influence intraocular pressure (IOP), which is a major risk factor for glaucoma. However, previous studies have shown inconsistent findings. Furthermore, research directly assessing the relationship between SBP and primary angle-closure glaucoma (ACG) remains limited. Therefore, this study aimed to analyze the relationship between SBP and…
Low Back Pain is one of the most frequently encountered musculoskeletal complaints in healthcare settings and is associated with activity limitation, reduced productivity, and impaired quality of life. Inflammatory processes are believed to contribute to the pathophysiology of LBP, particularly in conditions related to autoimmune diseases, leading to the use of systemic inflammatory biomarkers …
Background: The increasing use of online games along with technological development may lead to Internet Gaming Disorder (IGD), a behavioral addiction recognized in DSM-5 and ICD-11. University students are a vulnerable group due to academic demands and greater autonomy in time management. Methods: This study was a descriptive observational study with a cross-sectional design involving 561 acti…
Background : Diabetes mellitus is a non-communicable disease with a high prevalence and is frequently accompanied by hypertension, which increases the risk of vascular complications and imposes a substantial burden on quality of life and healthcare costs. It is estimated that approximately 40–80% of patients with diabetes also have hypertension; therefore, identifying risk factors associated …
Critically ill children have complex nutritional needs and require intensive nutritional support to prevent organ dysfunction. This study evaluated differences in gastrointestinal tolerance to intermittent and bolus enteral nutrition rates in children on mechanical ventilation. A single-blind, randomized, controlled trial was conducted from May 2024 to March 2025 at Dr. Mohammad Hoesin Hospital…
Contributing Factors to Peripheral Nerve Conduction in Children with Type 1 Diabetes Background: (T1DM) in children results from autoimmune destruction of pancreatic β-cells, leading to absolute insulin deficiency and chronic hyperglycemia. This condition poses a risk for long-term complications, including diabetic peripheral neuropathy, which may affect sensory, motor, or autonomic nerves and…
ABSTRAK Uji Diagnostik Nilai Titik Potong Lingkar Lengan Atas untuk Mendeteksi Gangguan Gizi pada Bayi Usia 1 – < 6 Bulan Gangguan gizi dapat didiagnosis dengan pemeriksaan antropometri baik menggunakan berat badan dan panjang badan ataupun menggunakan lingkar lengan atas (LiLA). Lingkar lengan atas telah digunakan secara rutin untuk mendiagnosis gangguan gizi pada anak usia 6-59 bulan. Pada …
Anak dengan diabetes melitus tipe 1 (DMT1) memiliki risiko lebih tinggi mengalami gangguan perilaku akibat beban penyakit kronis yang dialaminya. Gangguan ini dapat memengaruhi perkembangan sosial, prestasi akademik, dan kualitas hidup secara keseluruhan. Penelitian ini bertujuan mengetahui prevalensi dan faktor risiko gangguan perilaku pada anak dengan DMT1. Penelitian observasional analitik d…
Background: Pelvic organ prolapse (POP) is a gynecological condition in which the pelvic organs descend from their normal anatomical position into the vagina due to weakness caused by decreased strength in the ligaments. This condition can lead to complications that affect daily life, one of which is a reduced quality of life. One of the management approaches for POP is a surgical procedure cal…
Background. Hyperuricemia is a condition characterized by increased uric acid levels due to excessive activity of the xanthine oxidase (XO) enzyme. Arcangelisia flava is known to contain secondary metabolites, such as flavonoids, alkanoids, and terpenoids, which have been reported to exhibit potential inhibitory effects on XO. This study aims to determine the effect of variations in ethanol sol…
ABSTRACT Factors Associated Constipation in Children with Cerebral Palsy at Mohammad Hoesin Hospital Background: Cerebral palsy (CP) is a neuromotor disorder often accompanied by constipation, which can impair quality of life and worsen clinical outcomes. Several factors such as functional independence level, communication ability, use of antiepileptic drugs (AEDs), CP type, and diet are suspec…
Emotional and behavioral disorders (EBD) are prevalent mental health issues among adolescents, particularly in those with obesity. Obesity affects not only physical health but also has potential psychosocial consequences. This study aimed to determine the prevalence of EBD among obese adolescents and analyze associated risk factors, including metabolic parameters and lifestyle. This was an obse…
Background: Oral mucositis is a common side effect of chemotherapy in children with cancer, which can reduce quality of life and interfere with treatment. Standard therapies such as chlorhexidine are not fully effective, prompting the need for a safe and effective adjunctive therapy. Randu honey is known to have anti-inflammatory, antibacterial, and tissue-healing properties. Objective: To eval…
Background: Cognitive impairment is characterized by a decline in the ability to think, remember, and perform daily activities, and its prevalence increases with age. Globally, more than 57 million people were living with dementia in 2021, and this number is projected to reach 139 million by 2050. In Indonesia, the number of individuals with dementia is estimated to increase to 4 million by 205…
Background: End-stage renal disease requires patients to undergo long-term hemodialysis, which may lead to psychological impacts, including stress. The duration of hemodialysis is suspected to be associated with stress levels, yet data regarding patients at Dr. Mohammad Hoesin General Hospital Palembang remain limited. This study aims to analyze the relationship between the duration of hemodial…