Type 2 diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia resulting from insulin resistance and pancreatic β-cell dysfunction. Limitations of conventional therapies, which may cause adverse effects, have encouraged the development of antidiabetic agents derived from natural products. Paliasa leaves (Kleinhovia hospita Linn.) are known to contain bioactive compound…
Type 2 diabetes is a chronic disease that requires early detection to reduce the risk of complications. This study aims to design a web-based prototype Clinical Decision Support System (CDSS) to predict diabetes risk using the XGBoost algorithm and improve interpretability through the SHAP method. The dataset used was obtained from Kaggle and consisted of approximately 100,000 records with eigh…
The prevalence of type 2 diabetes mellitus in adults continues to increase, but the relationship between age, anxiety levels, and quality of life still shows varying results. This study aims to determine the relationship between age and anxiety levels with the quality of life of type 2 diabetes mellitus patients. This study used a quantitative method with a correlational design. The sample cons…
Program Pengelolaan Penyakit Kronis (Prolanis) merupakan sistem pelayanan kesehatan dan pendekatan proaktif yang diimplementasikan secara terintegrasi untuk mencegah dan mengendalikan penyakit kronis, termasuk DM. Keberhasilan program Prolanis dan PRB sangat bergantung pada kepatuhan pasien dalam melakukan kunjungan ulang secara teratur untuk pemantauan kondisi kesehatan dan penyesuaian terapi …
Chayote leaves (Sechium edule (Jacq.) Swartz) contain secondary metabolites like flavonoids, tannins, and saponins acting as antidiabetic agents through beta-cell protection. This study aimed to determine the antidiabetic activity of the ethanolic extract of chayote leaves (EECL) and evaluate its effect on pancreatic histopathology in hyperglycemic male Wistar rats. Hyperglycemia was successful…
Background : Diabetes mellitus (DM) is a chronic metabolic disorder characterized by elevated blood sugar levels caused by insulin resistance or impaired insulin secretion. The prevalence of type 2 diabetes mellitus continues to increase, especially in rural areas due to low public awareness and limited access to non-communicable disease control. Methods : This study used a case-control design …
Background: Diabetes Mellitus (DM) is a chronic disease that may lead to long-term complications, including cognitive impairment, particularly among the pre-elderly population. Glycemic control, measured by HbA1c, is a key component of DM management and is influenced, among other factors, by medication adherence. Good glycemic control may contribute to reducing the risk of cognitive impairment.…
Type II Diabetes Mellitus is a non-communicable disease closely associated with dietary patterns and physical activity. This study aims to determine the relationship between dietary patterns and physical activity with random blood glucose levels among Type II Diabetes Mellitus patients at Balai Agung Health Center, Sekayu. The study employed a quantitative method with a cross-sectional design. …
Background: Type 2 diabetes mellitus (T2DM) is characterized by hyperglycemia resulting from impaired insulin secretion or insulin resistance, with chronic low-grade inflammation playing a role in its pathogenesis. Diacerein has anti-inflammatory effects and improves insulin sensitivity; however, clinical evidence in Indonesia remains limited. Objective: To evaluate the effect of adding diacere…
The ability to do Self Care Management in patients with type 2 DM is low due to poor family support. Many family members in today's era of progress who are busy with their work cause people with type 2 DM if there are problems that are not paid attention to and feel burdensome to the family because of the disease experienced. Doing Self Care Management is very important because it can improve t…
Diabetes melitus is a chronic disease with a steadily increasing global prevalence, posing a significant concern in public health. This metabolic disorder is characterized by elevated blood glucose levels, which may lead to long-term complications if not managed properly. Conventional pharmacological therapies are commonly used to regulate glucose levels, but long-term use carries a risk of ser…
Diabetic retinopathy (DR) is a major complication of diabetes mellitus, characterized by damage to the retinal blood vessels and a high risk of blindness, particularly among individuals of productive age. Early detection of DR is essential, as the disease often presents no noticeable symptoms in its initial stages but can progress to permanent vision impairment if left untreated. This study aim…
Background: Type 2 Diabetes Mellitus (T2DM) was a chronic metabolic disease with an increasing prevalence, accompanied by hepatic complications such as Metabolic Dysfunction–Associated Fatty Liver Disease (MAFLD). The duration of T2DM affected the severity of metabolic disturbances, insulin resistance, and hepatic fat accumulation. However, data on the incidence of MAFLD at RSUP Dr. Mohammad …
Diabetes Mellitus is a chronic disease that requires long-term management, one of which is through dietary compliance. However, dietary non-compliance remains a common problem among Diabetes Mellitus patients in various healthcare facilities, including Makrayu Community Health Center of Palembang. Nurses' therapeutic communication plays an important role in improving patient understanding and m…
Adolescents represent a critical target group for early prevention efforts, as lifestyle behaviors adopted during this developmental stage contribute significantly to the risk of non- communicable diseases in adulthood, including diabetes mellitus. Diabetes mellitus is a global health concern with a continuously increasing prevalence. Unhealthy lifestyle patterns combined with low levels of kno…
Background: Semaglutide is a GLP-1 receptor agonist used as a therapy to improve glycemic control in patients with Type 2 Diabetes Mellitus. Although its use continues to increase globally, data regarding the utilization pattern of this drug in Indonesia, remains scarce. Objective: To determine the pattern of semaglutide use among T2DM patients at Siloam Sriwijaya Hospital Palembang from Januar…
Background: Diabetic foot ulcer is a serious complication of diabetes mellitus that can lead to amputation and increase morbidity and mortality rates. PEDIS (Perfusion, Extent, Depth, Infection, Sensation) Score is a classification system developed by the International Working Group on the Diabetic Foot (IWGDF) to assess the severity of diabetic foot ulcers and predict prognosis. This study aim…
The highest number of cases of diabetes mellitus in Ogan Ilir District in 2021 is the Puskesmas Indralaya with 1602 cases. The RPPT standard is at least 5%. While the DM RPPT indicator at the Puskesmas Indralaya is 0.12%. The purpose of this study is to evaluate the DM chronic disease management program (Prolanis) using a systems approach (input, process, output). This research uses qualitative…
Background : Diabetes mellitus is a non-communicable disease with a high prevalence and is frequently accompanied by hypertension, which increases the risk of vascular complications and imposes a substantial burden on quality of life and healthcare costs. It is estimated that approximately 40–80% of patients with diabetes also have hypertension; therefore, identifying risk factors associated …
Diabetic foot ulcers are one of the most common chronic complications in patients with uncontrolled diabetes mellitus and may lead to amputation. Inadequate knowledge of foot care increases the risk of developing diabetic foot ulcers; therefore, one preventive strategy is health education using PeKa (Foot Care) educational video media. This study aimed to determine the effect of the PeKa educat…
The prevalence of Type 2 Diabetes Mellitus (T2DM) continues to increase and has become a major global public health problem. This condition can be prevented through the adoption of healthy lifestyle behaviors. The effectiveness of preventive efforts is influenced by individuals' perceptions of disease risk and the perceived benefits of preventive actions. Inadequate or inaccurate perceptions ma…
Background: Diabetes mellitus (DM) is a chronic disease with an increasing prevalence on a global scale, including in Indonesia. Based on the International Diabetes Federation (IDF) data, Indonesia ranks fifth in the world in terms of the number of people living with diabetes. In 2021, there were an estimated 19.5 million individuals with diabetes in Indonesia, a figure that is predicted to rea…
ABSTRAK Kulit pisang kepok, yang mengandung sejumlah senyawa metabolit sekunder seperti flavonoid, telah diketahui memiliki potensi sebagai agen antidiabetes. Penelitian ini bertujuan untuk mengevaluasi seberapa efektif fraksi etil asetat dari kulit pisang kepok dalam menurunkan kadar glukosa darah. Penelitian melibatkan pembagian tikus percobaan ke dalam enam kelompok: kelompok normal (mendapa…
Background : Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia resulting from impaired insulin secretion or reduced insulin sensitivity. Hemoglobin A1c (HbA1c) reflects long-term glycemic control and is suspected to be associated with changes in lipid profiles. This study aimed to analyze the correlation between HbA1c levels and lipid profile parameters in pat…
Background: Type 2 diabetes mellitus (T2DM) is a chronic disease with an increasing prevalence and remains a major cause of morbidity and mortality due to metabolic and vascular complications. These conditions require sustained glycemic control, one of which is supported through the Chronic Disease Management Program (PROLANIS) by BPJS Kesehatan. However, its implementation across primary healt…
Non-communicable diseases (NCDs) currently constitute the majority of global health problems, one of which is diabetes mellitus. Diabetes mellitus is influenced by unhealthy lifestyle behaviors, such as poor dietary patterns, lack of physical activity, overweight or obesity, and smoking habits. The prevention of diabetes mellitus can be achieved through health education programs. Health educati…
Latar Belakang: Diabetes melitus (DM) adalah penyakit metabolik menahun, ditandai dengan hiperglikemia akibat dari defisiensi sekresi insulin atau resistensi terhadap kerja insulin ataupun keduanya. Penderita diabetes mempunyai risiko yang lebih tinggi terkena penyakit periodontal, disfungsi kelenjar ludah, karies gigi, kelainan pada mukosa, dan sensasi mulut terasa terbakar, sehingga dapat men…
Pada masa lampau badan yang gemuk merupakan lambang kemakmuran yang menentukan status sosial seseorang. Dengan pandangan tersebut maka ada kecenderungan banyak orang menginginkan badan yang gemuk bahkan sampai terjadi obesitas. Namun saat ini obesitas merupakan suatu penyakit kronik yang menjadi perhatian bagi dunia kesehatan. Seseorang yang mengalami obesitas mempunyai resiko lebih tinggi untu…
Diabetes Mellitus tipe 2 merupakan masalah utama kesehatan dunia yang jumlah penderitanya terus meningkat secara drastis di negara-negara industri baru dan negara sedang berkembang termasuk Indonesia yang menempati urutan terbesar ke empat di dunia. Oleh sebab itu penatalaksanaan penyakit ini membutuhkan perhatian serius termasuk cara pengobatan yang tepat agar tujuan terapi dapat dicapai dan d…
Obesitas merupakan suatu kelainan metabolisme yang paling lama tercatat dalam sejarah, mulai sejak jaman Mesir dan Yunani purba, bahkan hingga sekarang keadaan ini telah menjadi suatu permasalahan serius. Masyarakat sering tidak menganggap obesitas sebagai suatu penyakit tetapi justru merupakan sesuatu yang wajar bahkan dianggap sebagai suatu tanda kemakmuran. Padahal, sebenarnya obesitas mempu…