PENGARUH PEMBERIAN ESTRADIOL TERHADAP EKSPRESI BIOMARKER NEKROPTOSIS DAN PERA…

Introduction: Sepsis is a leading cause of morbidity and mortality in critically ill patients. While estradiol administration shows potential as a sepsis therapy, its impact on the necroptosis process remains unclear. This study aims to investigate the effect of estradiol administration on necroptosis and inflammation in a sepsis-induced Wistar rat model. Methods: This experimental study employ…

PENGARUH EKSTRAK ETIL ASETAT DAUN UBI JALAR UNGU (Ipomoea batatas L.) TERHADA…

Free radicals are molecules with unpaired electrons that can cause tissue damage through oxidative stress, accelerate aging, and trigger various diseases, including cancer. Antioxidants play an important role in warding off free radicals. Purple sweet potato leaves (Ipomoea batatas L.) are known to contain active compounds such as polyphenols, flavonoids, tannins and triterpenoids which have hi…

UJI AKTIVITAS DIURETIK FRAKSI ETIL ASETAT DAUN GAMAL (Gliricidia sepium) TERH…

Hypertension provides a major risk factor for cardiovascular and kidney disease. One of a therapy that used to treat a hypertension is diuretics. Gamal (Gliricidia sepium)contains flavonoid compounds which have diuretic effect. This study aims to determined activity of ethyl acetate fraction of gamal leaves as diuretic by measuring urine volume output and Na⁺, Cl⁻, dan K⁺ ion contents. Th…

PSIKOLOGI EKSPERIMEN

Ada lima perbedaan antara ilmu dan pengetahuan, yaitu dari segi penggunaan konsep dan teori, pengujian teori dan hipotesis, kontrol, kemampuan melihat hubungan antargejala, dan penjelasan terhadap gejala yang diobservasi. Suatu masalah dapat diteliti baik dengan penelitian eksperimental ataupun penelitian non-eksperimental. Ada dua kelebihan utama dari penelitian eksperimental, yaitu kemampuan …

TESIS EFEK EKSTRAK DAUN MAHONI (Swietenia mahagoni (L.) Jacq.) TERHADAP STRUK…

EFFECT OF MAHOGANY LEAF EXTRACT (Swietenia mahagoni L. Jacq.) ON THE HISTOLOGICAL STRUCTURE OF GASTRIC MUCOSA IN MICE (Mus musculus L.) Tegar Adi Wibowo 08082622327002 RESUME Traditional medicine has long been the most widely used form of treatment for various human diseases across the world. The World Health Organization (WHO) reports that approximately 80 of the population in developing count…

PENGARUH KOMBINASI POC KIRINYUH (Chromolaena odorata L.) DAN CANGKANG TELUR A…

This research aims to determine the effect of thecombination of liquid organic fertilizer from Kirinyuh (Chromolaena odorata L.) and Chicken Eggshell (Gallus gallus domesticus) on the growth of Cherry Tomato plants (Solanum lycopersicum Var. Cerasiforme). The method used in this study is an experimental method using a completely randomized design (RAL) with 5 treatments and 5 replications. The …

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAN FRAKSI HERBA SIRIH CINA (peperomia pell…

Chinese betel leaf (peperomia pellucida) contains secondary metabolite compounds such as flavonoids and terpenoids that have potential as antioxidants. This study aims to determine the effect of giving extracts and fractions of Chinese betel herb invivo on male Wistar rats induced oxidative stress by carbon tetrachloride (CCl4). The 30 test animals were divided into 6 treatment groups, namely t…

 EFEKTIVITAS EKSTRAK UBI JALAR UNGU (Ipomoea batatas L.) TERHADAP PENURUNAN …

Background: Purple sweet potato (Ipomoea batatas L.) is a carbohydrate food other than rice that is rich in antioxidant and anti-inflammatory compounds. There is few scientific research on the use of purple sweet potato as an herbal therapy ingredient to treat fibrosis. The purpose of this study was to determine the efficacy of purple sweet potato extract on reducing serum creatinine levels in …

PENGARUH PEMBERIAN EKSTRAK CARICA PAPAYA DALAM MENINGKATKAN KADAR HEMOGLOBIN …

Latar Belakang: Anemia defisiensi besi adalah suatu penyakit karena kadar pada eritrosit dan hemoglobin di bawah batas normal, berkurangnya kadar eritropoesis pada tubuh, sehingga tubuh mengalami kelemahan dan dapat menganggu aktivitas sehari-hari. Carica papaya atau tanaman papaya dikenal banyak memiliki manfaat sebagai obat tradisional obat hipertensi, malaria, malnutrisi, anemia, Penelitian …

EFEK PAPARAN SODIUM FLUORIDA TERHADAP KADAR GULA DARAH MENCIT

Introduction: Consumable water hygiene problems related to fluoride contamination are becoming an important issue in Indonesia. Indonesia's geographical location has many active mountains causes a lot of fluoride content in mountain air which is often used for consumable water. Fluoride has several impacts on health, one of which is the level effect of blood sugar. The research that has been ca…

EFEK EKSTRAK DAUN KERSEN (MUNTINGIA CALABURA L.) TERHADAP PROFIL HISTOPATOLOG…

Background: Acute gouty arthritis is an inflammation caused by MSU crystal deposition in the joint. Kersen leaves contain flavonoids that have anti-inflammatory and antioxidant activities. This study aims to determine the effect of kersen (Muntingia calabura L.) leaf extract on the histopathological profile of gout model rat joints. Methods: This research is an in vivo post-test-only control gr…

Strategi-Strategi Pengajaran: Memilih Strategi Berbasis Penelitian yang Tepat…

Edition

-

ISBN/ISSN

978-979-062-028-5

Collation

xii, 276 hlm. : ilus. ; 29 cm.

Series Title

-

Call Number

371.3 Sil s

EFEK EKSTRAK DAUN KERSEN (Muntingia calabura L.) TERHADAP KADAR TNF-α PADA T…

Background: Acute gout arthritis is an inflammation due to the accumulation of MSU crystal in the joint which leads to pain, swelling, and an increase in proinflammatory cytokines such as TNF-α. Cherry leaves contain flavonoids that have anti-inflammatory activity which plays a role in inhibiting the production of TNF-α. This study aims to determine the anti-infammatory effect of cherry leave…

EFEKTIVITAS PEMBERIAN EKSTRAK BAWANG MERAH TERHADAP PENURUNAN KADAR GULA DARA…

Background: Diabetes mellitus is a chronic disease characterized by the pancreas being unable to produce insulin or when the body cannot use insulin properly. This situation causes the body to experience hyperglycemia and can result in body damage and even organ and tissue failure. The main goal of therapy for diabetes mellitus sufferers is controlling blood sugar levels. Shallots (Allium cepa …

EFEK PAPARAN SODIUM FLUORIDA TERHADAP PERILAKU TERKAIT FUNGSI KOGNITIF DAN RE…

Background: Fluoride is one of the minerals that are abundant in nature. WHO has declared the existence of fluorosis endemic areas due to excessive consumption. Fluoride has a neurotoxicity effect and impaired the cognitive function in memory domain. Memory formation is closely related to glutamate and its receptors (NMDA and AMPA). This study aimed to determine the effect of sodium fluoride ex…

Strategi dan Model Pembelajaran; Mengajarkan Konten dan Keterampilan Berfikir…

-

PENGARUH FAKTOR PERTUMBUHAN PLATELET TERHADAP KADAR TUMOR NECROSIS FACTOR ALP…

Osteoarthritis (OA) merupakan bentuk penyakit sendi yang paling umum ditemukan di dunia dan diasosiasikan oleh usia. OA bermula saat faktor katabolik, sepeti TNF-α, yang berperan pada metabolisme kartilago mendominasi dan menekan faktor anabolik membuat degradasi kartilago terjadi. Faktor pertumbuhan yang didapat dari platelet memiliki peran krusial dalam penyembuhan jaringan dan respons imun.…

PENGARUH FAKTOR PERTUMBUHAN PLATELET TERHADAP KADAR ALPHA-SMA PADA TIKUS PUTI…

Osteoarthritis (OA) adalah gangguan sendi yang paling umum dan merupakan penyebab utama disabilitas dengan dampak sosial ekonomi yang besar dan terjadi akibat ketidakseimbangan mediator proinflamasi dan antiinflamasi atau aktivitas anabolik dan katabolik. Penelitian ini bertujuan untuk mengetahui pengaruh Faktor Pertumbuhan Platelet (FPP) terhadap kadar Alpha-SMA. Penelitian ini merupakan studi…

UJI ANTIHIPERURISEMIA EKSTRAK ETIL ASETAT BATANG KAYU KUNING (ARCANGELISIA FL…

Background: Stem of yellow wood (Arcangelisia flava) is a plant that are efficacious as an antihyperuricemic. This is because it contains secondary metabolites in the form of alkaloids, flavonoids, terpenoids, and tannins. Previous research conducted in vitro research on ethyl acetate extract from stem of the yellow wood (Arcangelisia flava) which has been proven to be antihyperuricemic. This s…

PENGARUH FAKTOR PERTUMBUHAN PLATELET TERHADAP KADAR INTERLEUKIN-1β (IL-1β) …

Osteoarthritis (OA) adalah penyakit degeneratif tulang rawan sendi yang diikuti oleh peradangan rongga synovial. Interleukin-1β (IL-1β) bertanggung jawab pada proses terjadi OA. Faktor pertumbuhan platelet diprediksi mampu memodulasi penyembuhan OA. Tujuan penelitian ini untuk mengetahui pengaruh pemberian FPP terhadap kadar IL-1β. Eksperimental in vivo menggunakan pendekatan post-test only …

EVALUASI MIKROANATOMI GINJAL PEMBERIAN SELF NANO EMULSION (SNE) EKSTRAK TEH P…

White tea has pharmacological activity as an antidiabetic because it contains polyphenol compounds in the form of epigallocatechin gallate (EGCG) which can inhibit the α-glucosidase enzyme so that blood glucose levels can be returned within normal limits. However, plant extracts have low oral bioavailability, so the formula in the form of SNEDDS (Self-Nano Emulsifying Drug Delivery Systems) is…

UJI AKTIVITAS ANTIOKSIDAN FRAKSI ETIL ASETAT DAUN BELUNTAS (Pluchea indica L.…

Daun beluntas (Pluchea indica L.) mengandung metabolit sekunder seperti flavonoid yang berpotensi sebagai antioksidan. Tujuan penelitian ini adalah untuk mengetahui karakterisasi, jumlah kadar flavonoid total, dan pengaruh pemberian fraksi etil asetat daun beluntas terhadap kadar MDA, aktivitas enzim katalase, gambaran makroskopik dan histopatologi hepar tikus yang diinduksi CCl4, serta mengeta…

UJI AKTIVITAS ANTIOKSIDAN FRAKSI ETANOL DAUN MELINJO (Gnetum gnemon L.) TERHA…

Melinjo leaves (Gnetum gnemon L.) have been widely researched in their use as an efficacious medicinal plant. Flavonoid as secondary metabolite compounds contained in melinjo leaves have the potential to be antioxidants. Antioxidant activity test on the ethanol fraction of melinjo leaves was tested with in vivo method with the aim of determining its effect on malondialdehyde (MDA) levels, catal…

Rancangan Percobaan: Teori & Aplikasi, Edisi Ketiga

Buku ini menuntun peneliti dan mahasiswa dalam memahami dan menguasai falsafah dan penerapan ilmu rancangan percobaan dalam penelitiannya.

UJI EFEK GASTROPROTEKTIF EKSTRAK ETANOL RIMPANG TEMULAWAK (Curcuma Xanthorrhi…

Rimpang temulawak mengandung senyawa metabolit sekunder berupa flavonoid, steroid, triterpenoid dan tannin. Penelitian ini bertujuan untuk mengetahui efek gastroprotektif ekstrak etanol rimpang temulawak melalui parameter makroskopik lambung, volume, pH, keasaman total cairan lambung, kadar mucin, serta pengamatan mikroskopik. Tikus dibagi menjadi 6 kelompok yaitu kelompok normal, kontrol posit…

UJI AKTIVITAS ANTIOKSIDAN FRAKSI ETIL ASETAT DAUN SALAM (SYZYGIUM POLYANTHUM …

Ketidakseimbangan antara jumlah radikal bebas dan antioksidan endogen tubuh menimbulkan stress oksidatif yang dapat menyebabkan kerusakan sel. Tubuh memerlukan asupan antioksidan dari luar tubuh, baik sintetis atau alami. Salah satu sumber antioksidan alami adalah daun salam yang mengandung flavonoid yang dapat menstabilkan radikal bebas. Pengujian aktivitas antioksidan fraksi etil asetat daun …

PENGARUH PEMBERIAN FRAKSI ETANOL DAUN UBI JALAR UNGU TERHADAP ALIRAN DAN PARA…

Purple sweet potato leaves contain alkaloids, flavonoids, quinones, steroids, monoterpenes, sesquiterpenes, polyphenolics and tannins which are anti-atherosclerotic. This study aims to determine the effect of giving the ethanol fraction of purple sweet potato leaves on rat blood flow and coagulation factors and its effect on the histopathological picture of the rat aorta induced by high-fat sup…

UJI AKTIVITAS EKSTRAK ETANOL DAUN KARDIA (Bellucia pentamera Naudin) TERHADAP…

Luka terbuka merupakan luka yang mengakibatkan kerusakan pada kulit jika diabaikan akan terjadi infeksi. Tanaman obat yang telah diteliti dan dimanfaatkan untuk penyembuhan luka terbuka salah satunya yaitu daun kardia (Bellucia pentamera Naudin). Daun kardia (Bellucia pentamera Naudin) mengandung senyawa flavonoid, saponin, tannin, fenolik, dan triterpenoid sebagai antijamur, antivirus, antibak…

EFEK PEMBERIAN SNACK BAR EKSTRAK DAUN PEGAGAN (Centella asiatica L.) KOMBINAS…

Gotu Kola (Centella asiatica L.) and gambier (Uncaria gambir Roxb.) is a plant that is believed to have many benefits. The high antioxidant content, especially flavonoids, triterpenoids, polyphenols, saponins from gotu kola and gambier leaves are believed to improve memory. This study aims to determine the levels of flavonoids, levels of proximate snack bar characteristics , and to determine th…

UJI EFEK ANTIULCER EKSTRAK ETANOL RIMPANG TEMU MANGGA (Curcuma amada Roxb.) T…

Rimpang temu mangga (Curcuma amada Roxb.) mengandung metabolit sekunder seperti flavonoid, kurkuminoid dan fenolik yang berpotensi memiliki aktivitas antiulcer. Penelitian ini bertujuan untuk mengetahui efek antiulcer ekstrak etanol rimpang temu mangga (EERTM) yang diinduksi etanol absolut. Efek antiulcer ini dilihat dari parameter seperti, evaluasi lesi lambung, pengukuran volume, pH, keasaman…