Background: Head injury is the highest cause of death among productive age group. Epidural hematoma made massive bleeding that causes rapid deterioration. Surgery is needed for life saving management.Varied condition could affect the clinical outcome of surgery. Therefore, this study was conducted. Methods: This study was an observational analytical with cross-sectional design using secondary d…
Buku ini memfokuskan pada perubahan proses penyakit mengenai keseimbangan dinamis tubuh, atau homeostasis, pendekatan konseptual yang dirancang untuk mengombinasikan pengetahuan ilmu dasar klinis. Buku teks ini dibagi menjadi beberapa bagian, dimulai dengan prinsip-prinsip patofisiologi umum dan selanjutnya pembahasan berdasarkan pendekatan sistem tubuh. Pada edisi ke-6 ini dibahas peneli…
Background: Abnormal Uterine Bleeding (AUB) is a common gynecological problem. The histopathological features of AUB vary widely from normal to pathological features. This study was aimed to determine clinical characteristics and histopathology of patients with AUB in Central General Hospital Dr. Mohammad Hoesin Palembang. Methods: This study was a descriptive observational study with a cross s…
Background: Soil transmitted helminths (STH) infections are major public health problems in developing countries, especially Indonesia. Consuming improperly washed raw vegetables is a major way in which pathogens are transmitted into the humans body. Most people do not wash raw vegetables that will be consumed properly. Therefore, this study was conducted to know the contamination of Soil Trans…
Background : Soil Transmitted Helminths (STH) infection is a main problem in the world especially in tropical regions such as Indonesia. This infection can be transmitted by eating raw vegetables that contaminated by STH. This study was aimed to know whether there was a contamination of STH eggs or not on edible raw vegetables at street food stalls and restaurants in Kelurahan Lorok Pakjo Palem…
Introduction. Research on honey has proven the benefits of honey’s antibacterial. The antimicrobial potential each honey can vary. Escherichia coli is a harmless Gram negative bacterium, however some strains can be pathogenic. Antibiotic resistance to Escherichia coli is increasing rapidly so it is necessary to find alternative antibacterials. Tembesu bitter black honey is honey from Tembesu …
Introduction. Hepatitis is inflammation of the liver. This condition can resolve on its own or it can progress to fibrosis (scarring), cirrhosis or liver cancer. Viral hepatitis is the world's most common cause of hepatitis from other infections, toxic substances such as alcohol, certain drugs and autoimmune diseases can also cause hepatitis. The most common route of transmission is the perinat…
Background: Malignant melanoma is a malignant tumor of melanocytes. The incidence of malignant melanoma has increased every year. In Indonesia, melanoma accounts for 7.9% of all skin malignancies. Tumor infiltrating lymphocytes (TILs) is a reflection of a good immune response against melanoma cells. It is known that TIL infiltrating provides a good prognosis. This study aims to determine the re…
Background: PYY (1-36), a polypeptide consisting of 36 amino acid structures, is known to play a role in increasing the growth and survival of beta cells through NPY1R activation in the pancreas, which ultimately leads to glycemic balance. (P3L31P34)PYY(1-36) is a PYY (1-36) analog that is resistant to DPP-IV degradation and has high selectivity to NPY1R. This study aims to identify the charact…
Background: Respiratory distress is one of the causes for newborns to be treated in a neonatal intensive care unit. Respiratory distress can have some serious consequences for babies such as respiratory failure, cardiac arrest, and even death. About 7% of newborns often experience respiratory problems. Most cases of respiratory problems in newborns are found in infants with a history of preterm…
Background: Covid-19 is a respiratory tract infection caused by the novel coronavirus (nCov). Nasal irrigation is one of the efforts to prevent Covid-19. Nasal irrigation is an act of flushing saline solution into the nasal cavity. The purpose of this study was to determine the level of knowledge, attitudes, and practices of the community regarding Nasal irrigation during the Covid-19 pandemic.…
Background. HIV (Human Immunodeficiency Virus) is a retrovirus that causes the death of CD4 + T cells and immune deficiency. Opportunistic infections are a major cause of HIV-related morbidity and mortality, one of the most common form is opportunistic brain infections. The aim of this study was to identify the characteristics of opportunistic brain infections in HIV patients at RSUP dr. M. Hoe…
Background: Carpal tunnel syndrome is peripheral compression of the median nerve at the level of the wrist joint. Carpal tunnel syndrome characterized by pain in the hand, numbness, and tingling with the most common sensation that can be felt in the thumb, index finger, middle finger, and 1/2 ring finger on the radial side. Carpal tunnel syndrome is more prevalent among people with occupations …
Background: Binahong plant (Anredera cordifolia (Ten.) Steenis) leaves contain alkaloids, flavonoids, saponins, trepenoids, and ascorbic acid which have antioxidant activity. The purpose of this study was to determine the phytochemical content and antioxidant activity of binahong leaf infusion. Method: This research is an experimental study by conducting antioxidant testing on the leaves of bin…
Background. Vaginal discharge is excessive vaginal secretion from the vulva or excessive fluid from the vagina that is not blood. Vaginal discharge consists of two types, namely physiological and pathological. In physiological, vaginal discharge is characterized by clear vaginal secretion sometimes white, thick, odorless, itchy, and painless. While in pathological, vaginal discharge is obtained…
Background: Acne vulgaris (AV) is an inflammatory process of pilosebaceous follicles due to presence of Propionibacterium acnes often found in adolescents. Factors affecting AV include psychological stress and sleep quality. Survey stated 83% of adolescents experience stress while 43% have poor sleep quality in which could worsen AV. This study aimed to determine the relationship between stress…
Introduction: Coronary heart disease (CHD) is the number one leading cause of death. It is the most common cardiovascular disease. Coronary heart disease is a condition when the oxygen supply fails to fulfil oxygen demand. Endothelial dysfunction is the main cause of CHD that leads to the formation of atherosclerosis. This study was done to find which of the cardiovascular risk factors were ass…
Metabolic syndrome is still a risk factor for coronary heart disease. This study aims to analyze the relationship between metabolic syndrome and coronary heart disease in women. This study is an observational analytic study using a cross-sectional design on 138 samples selected using consecutive sampling method and data were collected through observation of the medical records of patients at dr…
Background. A head injury is trauma caused by a direct or indirect physical impact on the head and is blunt or sharp. Head trauma can cause neurological dysfunction which can be temporary / temporary or permanent / permanent. Head injuries occurred mostly due to land transportation accidents (47.7%), falls (40.9%), blunt and sharp object collisions (7.3%), and falling objects (2.5%). Head injur…
Hyaline Membrane Disease merupakan komplikasi yang sering didapatkan pada bayi prematur. Hyaline membrane disease adalah suatu sindroma yang terjadi pada bayi prematur karena imaturitas struktur paru dan insufisiensi produksi surfaktan. Karakteristik HMD sebagai berikut diantaranya, yaitu riwayat penyakit ibu (diabetes), jenis kelamin, usia kehamilan, berat badan lahir, cara persalinan, dan jum…
Latar Belakang : Penggunaan Thrombocyte Concentrates (TC) mengalami peningkatan. Terdapat 2 jenis trombosit untuk keperluan medis di Rumah Sakit Moehamad Hoesin Palembang, trombosit yang dibuat di RSMH menggunakan metode apheresis dan trombosit dari Palang Merah Indonesia menggunakan whole blood donor tunggal yang diambil dari platelet-rich plasma. Pengawasan mutu (Quality Control=QC) dilakukan…
Introduction: Breast cancer is a multifactorial disease. Most of the breast cancer risk factors are hormonal risk factors that associated with the length of exposure to estrogen hormone. This study is aimed to know the description of hormonal risk factors of breast cancer patients in RSUP Dr. Mohammad Hoesin Palembang. Method: This study is a descriptive-observational study with cross-sectional…
Catfish is a freshwater fish that is often found in South Sumatra. In the fillet industry, skin is one of the waste processing fisheries products and is considered to have no economic value and can be detrimental. This waste is usually not used and disposed of. This study aims to determine the results of the phytochemical analysis of catfish (Pangasius sp.) The skin extract using solvents with …
Backckground: Catfish (Pangasius Sp.) is a kind of fish that is included in the catfish group which is one of the superior freshwater fish commodities consumed by Indonesian people, especially the people of South Sumatra province. The nutritional content of catfish meat contain many benefits for human body. Catfish meat contain secondary metabolites such as alkaloids, flavonoids, tannins, sapon…
Background: The problem of over nutritional status (obesity) has increased every year, which occur not only in adults but also in children and adolescents. Obesity is defined as an excess or abnormal fat accumulation which can lead to various health problems. One of the manifestation of these problems is dyslipidemia, a condition characterized by an increase or decrease in lipid fraction. The a…
Urticaria, which is commonly called hives or hives, is a disease caused by a vascular reaction in the form of skin edema mixed with itching, occurs quickly and lasts 1-2 hours, can also last longer and lasts 36 hours. Urticaria is divided into two, namely chronic urticaria that occurs less than 6 weeks and chronic urticaria occurs more than 6 weeks.The incidence of urticaria is quite high in va…
Diabetic retinopathy is a chronic, potentially vision-threatening, progressive disease of the retinal microvascularis associated with prolonged hyperglycemia and other conditions associated with diabetes mellitus such as hypertension. Diabetic retinopathy is the main cause of vision loss in type 1 DM patients and has many risk factors. This study aims to determine the incidence and risk factors…
The variety of contraceptions available causes many pregnant women to experience difficulties in determining which type of contraception to choose. Intra Uterine Device (IUD) is one of the Long-Term Contraception Methods (MKJP) whose use is still low compared to other types of contraception. One of the factors causing this is the pregrant women’s level of knowledge about the IUD. The purpose …
Background: Diffuse Large B Cell Lymphoma (DLBCL) is a malignancy derived from malignant transformation of B cells from the germinal center. This type of non-Hodgkin's lymphoma is the most common and represents about 30-40% of all cases. The tumor microenvironment of B-cell lymphoma plays an important role in the regulation of tumor cell survival and proliferation. Plasma cells in the tumor mic…
Background: Corona Virus Disease 2019 or COVID-19 is a disease caused by the corona virus and has emerged with a rapid spread and death since it was first discovered in Wuhan, China. Hemostasis parameters such as fibrinogen, D-dimer, PT and aPTT were increased in a number of COVID-19 patients. The purpose of this study was to determine the comparison of hemostasis parameters in patients with CO…