Cases of hypercholesterolemia continue to increase every year and have become one of the major risk factors for cardiovascular disease. Modern antihypercholesterolemic drugs, such as statins, often cause adverse side effects rhabdomyolysis, creating the need for safer therapeutic alternatives. Pelawan leaves (Tristaniopsis merguensis) are a natural ingredient containing various bioactive compou…
The demands of 21st-century learning emphasize the strengthening of higher-order thinking skills (HOTS), particularly in abstract chemistry topics such as reaction rates, while interactive learning media capable of optimally training students’ HOTS remain limited. This study aimed to develop interactive multimedia on reaction rate material to enhance the Higher-Order Thinking Skills (HOTS) of…