Introduction : Erythema nodosum leprosum (ENL) also known as type 2 leprosy reaction is a systemic acute inflammation reaction that is found in 30-50% of all leprosy patients. Leprosy patients with type 2 leprosy reaction is at risk of developing permanent damage or even disabilities. To this point, the diagnosis of ENL depends only on clinical observation and tends to be delayed. ENL is an acu…
Leprosy is a chronic granulomatous disease. Leprosy is caused by M. leprae. However, not all exposure to M. leprae caused the disease. The condition of the host immune system determines the pathogenesis of leprosy. IL-10 work as a pro- and anti-inflammatory cytokine. Polymorphism in the IL-10 gene promoter affects the amount of IL-10 secretion. The amount of IL-10 secretion determines the bodyâ…
Kusta adalah penyakit infeksi kronik yang disebabkan oleh Mycobacterium leprae terutama menyerang saraf perifer dan kulit. Penderita kusta sering ditolak oleh masyarakat karena persepsi masyarakat yang salah tentang kusta. Kesalahpahaman tentang kusta yang berkembang di masyarakat dipengaruhi oleh pengetahuan, kepercayaan dan sikap masyarakat sehingga menimbulkan suatu perilaku terhadap pe…