Background. Acute Lymphoblastic Leukemia (ALL) is the most common hematologic malignancy in children, characterized by abnormal lymphoblastic. Prognosis and treatment evaluation are generally performed through invasive bone marrow examination as gold standard. Therefore, non-invasive hematological parameters are needed to predict prognosis. Platelet involved in bone marrow activation and hemost…
Background: Nasopharyngeal non-Hodgkin lymphoma (NHL) is an extranodal lymphoid malignancy of the head and neck that is treated with systemic chemotherapy. Chemotherapy may be accompanied by changes in hematological parameters; therefore, monitoring of hematological profiles is required. Data regarding the hematological profile of patients with nasopharyngeal NHL in Indonesia are still limited.…
Anemia in pregnancy is a health problem that occurs in developing countries and contributes to high morbidity rates in pregnant women. This research aims to find out what factors influence pregnant women compliance in consuming blood supplement tablets of the Alang Alang Lebar City Health Center Palembang working region. This research is descriptive analytic with a cross sectional design. The s…
Background: Thalassemia is inherited anemia by autosomal recessive manner with a disruption in hemoglobin synthesis and caused a decrease amount of hemoglobin and anemia. Routine blood transfusions carried out by sufferers and parent's sociodemographic factors can cause an increased psychological burden on the patient's parents. This study investigated the relationship between the incidence of …
Background: Iron deficiency anemia (IDA) is a lack of iron availability in the body. The incidence of IDA in children in Indonesia ranges from 40‒50%. The diagnosis is generally made based on anamnesis, physical examination, and laboratory results. Examination of iron status is one of the examinations that are common, sensitive, and a diagnosis of IDA in Indonesia at this time by carrying out…
Prediabetes is a condition when the blood glucose range is above normal but does not include the classification of Diabetes Mellitus. Prediabetes prevalence in Indonesia in the age range of 15-24 years 10.7% had impaired fasting glucose (IFG) and 16.8% impaired glucose tolerance (IGT). Prediabetes is influenced by both non-modifiable and modifiable risk factors. The purpose of this study was to…
Introduction : COVID-19 is a disease caused by SARS-CoV-2 which first appeared in Wuhan, China. Uncontrolled coronavirus infection causes more macrophage infiltration and can cause systemic cytokine storm with microcirculatory dysfunction which eventually leads to sepsis. Early identification of sepsis is useful for eary prognosis and guidance in making therapeutic decisions, this will reduce m…
Background: Hypercholesterolemia is a condition when total cholesterol increases beyond its normal value (≥200 mg/dL). Hypercholesterolemia is the main cause of atherosclerosis in blood vessels, such as in peripheral arterial disease, myocardial infarction, and stroke. The most commonly antihypercholesterolemia drug that used in Indonesia is simvastatin. Irrational use of medicine is still th…
Background: Thalassemia is a hemolytic disease that is inherited as autosomal recessive form disturbance synthesis globin chain up to occur decline cell blood redness and chronic anemia and must blood transfusion and, iron chelation therapy is needed. Assistance during therapy causes psychosocial disorders of parents and influences the occurrence of depression. The aim of this study was to dert…
Background: Coronavirus Disease 2019 (COVID-19) is an infectious respiratory disease that spreads globally and was declared as a pandemic in March 2020. Laboratory examinations need to be carried out on patients infected with COVID-19 to establish a diagnosis. On laboratory examination, abnormal results were found, namely lymphopenia. Such results are often associated with significant changes i…
Latar Belakang: Thalassemia merupakan genetik autosomal resesif karena kelainan pada gen pengkode protein globin. Hal tersebut menyebabkan gangguan sintesis globin berupa tidak ada atau menurunnya rantai yang membentuk struktur hemoglobin sehingga hemoglobin tidak terproduksi dengan baik. Penderita thalassemia anak mengalami ketidak efektifan dalam proses eritropoiesis dan percepatan penghancur…
Latar Belakang: Diffuse large B-cell lymphoma (DLBCL) merupakan neoplasma sel-B sedang atau besar yang pola pertumbuhanya secara difus dengan inti besar. Sekitar 30-40 % kasus limfoma merupakan DLBCL. Berdasarkan fitur molekuler dan cell of origin (COO), DLBCL dibagi menjadi subtipe germinal center B-cell (GCB) dan activated B-cell (ABC) / non-germinal center B-cell (non-GCB). Anemia menjadi sa…
Latar Belakang : Kusta merupakan suatu penyakit infeksi kronik yang disebabkan oleh M. Leprae. Manajemen pengobatan kusta telah diatur sepenuhnya dalam PMK No. 11 Tahun 2019 Tentang Penanggulangan Kusta. Regimen pengobatan kusta adalah Multidrug Therapy (MDT) yang merupakan kombinasi dari obat rifampisin, dapson, dan klofazimin. Salah satu komponen MDT dalam pengobatan kusta adalah dapson yang …
Background: Thalassemia is a group of hemolytic diseases from genetic disorders resulting from a decrease in the synthesis of alpha or beta chains of hemoglobin (Hb). A particular craniofacial cephalometric picture is found in the form of mild skeletal class II clinical manifestations. The anterior cranial base becomes a benchmark or reference sector in the measurement of dentofacial structures…
Latar Belakang: Thalassemia adalah kelainan bawaan yang terjadi akibat gangguan pada sintesis hemoglobin. Indonesia sendiri kasus thalassemia diperkiraan memiliki angka kelahiran 2.500 anak dengan thalassemia setiap tahunnya. Pada pasien thalassemia sering ditemukan kelainan skeletal kelas 2. Sudut interinsisal merupakan sudut yang dibentuk dari perpotongan sumbu gigi incisivus rahang atas dan …
Attempt to detect cervical cancer with pap smear examination are prone to errors because it is done manually. In this case, a medical image processing system is needed to reduce cervical cancer misdiagnosis by applying semantic image segmentation using Convolutional Neural Network (CNN) method. One of the CNN architectures that has good performance in biomedical image segmentation is U-Net. Som…
Anemia pada remaja putri sampai saat ini masih cukup tinggi. Jika mayoritas remaja putri menderita anemia, lebih mudah terkena penyakit, menurunkan aktivitas remaja, prestasi belajar serta menurunkan kebugaran remaja, berpengaruh besar pada saat kehamilan dan persalinan. Tujuan penelitian ini adalah menganalisis Upaya Menurunkan Kejadian Anemia Pada Remaja Melalui Program Peduli Kesehatan Remaj…
Latar Belakang: Anemia pada ibu hamil merupakan masalah kesehatan yang dapat mengancam kondisi ibu dan janin, dan merupakan kasus insiden tinggi. Faktor penyebab anemia pada ibu hamil diantaranya umur, paritas, tingkat pendidikan, status ekonomi, kepatuhan konsumsi tablet Fe dan keteraturan melakukan kunjungan antenatal care. Tujuan penelitian ini mengetahui hubungan kunjungan antenatal care te…
Anemia is a body’s lack of micronutrient intake condition such as iron so that the hemoglobin level in the body is low and frequently happens in adolescents. Adolescents who experience anemia can cause disturbed growth and decrease body endurance so that they easily get the disease, and in the long term affect future pregnancy and childbirth. Moringa leaf and hanjeli are natural food ingredie…
Anemia pada ibu hamil merupakan masalah kesehatan masyarakat di dunia maupun negara berkembang, salah satunya Indonesia. Anemia saat kehamilan merupakan kondisi menurunnya kadar hemoglobin dari nilai normal (Hb < 11 g/dL). Anemia kehamilan disebabkan oleh beberapa faktor seperti karakteristik ibu (paritas, pendidikan ibu, pendapatan keluarga) dan asupan mikronutrien (zat besi, asam folat, vitam…
Background: Acute lymphoblastic leukemia (ALL) is a type of leukemia that causes organomegaly and organ failure with the characteristics of proliferation and accumulation of pathological cells of the lymphopoietic system. Leukemia can harm all ages, although the most common occurrence is in children. Pain is the most common nursing problem in children with ALL. Objective: This paper aims to des…
Albumin is the most abundant protein in the blood plasma and has many important functions. The condition where the albumin levels are below normal value is called hypoalbuminemia. Hemoglobin is a protein that act as a carrier of oxygen and carbon dioxide in the body. The condition where the hemoglobin levels are below normal value is called anemia. Hypoalbuminemia and anemia are commonly found …
Thalassemia disease and routine treatment for a long period of time in children with thalassemia cause various complications such as enlarged liver and lymph, growth problems, delayed puberty, and heart failure. The continuity of the treatment process and the prevention of complications in children with thalassemia are supported by parents. Parents need to be given a good knowledge therefore th…
Riskesdas in 2018 stated that the incidence of anemia is still high in adolescent girls, based on the author's search for adolescent girls at SMPN 1 Indralaya Utara around 80% didn’t know about anemia. This needs to be followed up with health education as accordance as the current trend of adolescents who like watching videos. This research aims to determine the influence of video media on ad…
Background: Thalassemia is hemolytic anemia caused by disruption of hemoglobin formation in erythrocytes. The percentage of carriers alpha thalassemia Indonesia is estimated to be around 1-10% and beta-thalassemia is 3.7%, with the spread in Java of 3.4%, Palembang 7%, and in Makassar 8% of the total population of Indonesia. By increasing the awareness of medical students on the prevention of t…