Background: Diffuse large B-cell lymphoma (DLBCL) is the most common subtype, with 150,000 new cases yearly. Roughly 40% of patients who receive rituximab in addition to vincristine, cyclophosphamide, doxorubicin, and prednisone treatment have primary refractory disease or recurrence. Although the Ann Arbor stage could determine DLBCL prognosis, new biomarkers are needed to stratify patient pro…
Latar Belakang: Sepsis akibat infeksi jamur paling sering ditemukan di ICU dan dikaitkan erat dengan luaran yang buruk. Infeksi jamur dikaitkan dengan angka kematian tinggi, waktu perawatan di ICU dan penggunaan ventilator lebih lama. Penggunaan obat anti jamur empiris yang tepat dikaitkan dengan penurunan angka mortalitas. Penelitian ini bertujuan untuk menganalisis hubungan penggunaan obat an…
Background: Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality among critically ill patients. Coagulation abnormalities are frequently observed in TBI patients and may significantly influence clinical outcomes, including intensive care unit (ICU) length of stay, duration of mechanical ventilation, and mortality. This study aims to evaluate the association betwe…
Background: PaCO₂ plays a crucial role in cerebral autoregulation and perfusion. Both hypercapnia (increased PaCO₂) and hypocapnia (decreased PaCO₂) may have detrimental effects. Alterations in PaCO₂ can contribute to clinical outcomes in traumatic brain injury (TBI) patients after craniotomy. Methods: An observational analytic cohort was conducted in the ICU of Dr. Mohammad Hoesin Hosp…
Background: Sepsis is a leading cause of death in intensive care units (ICU), with high mortality rates. As a routine, inexpensive, rapid, and readily accessible test, the complete blood count (CBC) has the potential to predict mortality. This study aimed to analyze the accuracy of CBC parameters as mortality predictors in ICU patients with sepsis. Methods: A retrospective cohort study was cond…
Tujuan. Membandingkan efek premedikasi klonidin 2 pg/kgbb dengan klonidin 4 pg/kgbb secara oral dalam mencegah respon kenaikan tekanan darah dan laju nadi akibat laringoskopi intubasi Metodelogi. Penelitian ini merupakan uji klinik berpembanding secara tersamar ganda, didapatkan 66 subjek yang dibagi atas 2 kelompok yaitu 33 subjek kelompok 2 pg/kgbb dan 33 subjek kelompok klonidin 4 pg/kgbb. P…