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PREPARASI DAN UJI AKTIVITAS ANTIDIABETES NANOSUSPENSI EKSTRAK DAUN MELINJO (G…
Melinjo leaves are known to have pharmacological activity as antidiabetics because they contain flavonoid compounds that can reduce blood glucose levels with their ability to act as antioxidants that protect β-cell damage as insulin producers and can increase insulin sensitivity. The effectiveness, bioavailability, and solubility of extracts tend to be low, so the formula in the form of nanosu…
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- xix, 101 hlm.; ilus.; tab.; 29 cm.
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- T1449962024
UJI AKTIVITAS ANTIDEPRESAN EKSTRAK ETANOL DAUN CEMPEDAK (Artocarpus champeden…
Cempedak (Artocarpus champeden) leaves contain flavonoids that are efficacious as antioxidants which are thought to have potential as antidepressant activity. This study aims to determine the effect of cempedak leaf ethanol extract as an antidepressant and find out the best concentration of cempedak leaf ethanol extract as an antidepressant. Parameters observed included length of fall, immobili…
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- xvii, 99 hlm.; ilus.; tab.; 28cm
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- T1440172024
UJI AKTIVITAS HAIR SERUM NANOPARTIKEL EKSTRAK DAUN TEH (CAMELLIA SINENSIS L.)…
Hair serum is one of the cosmetic preparations that has a high concentration of active ingredients so that its effectiveness can be felt faster. Tea leaves contain about 42% polyphenolic compounds in the form of catechins that can stimulate cell proliferation in hair dermal papilla cells by suppressing the production of Tumour Necrosis Factor alpha (TNF-alpha) that triggers baldness. This study…
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- xvii, 69 hlm.; ilus.; 29 cm
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- T1319032023
UJI AKTIVITAS EKSTRAK ETANOL DAUN SUNGKAI (Peronema canescens Jack.) TERHADAP…
Penelitian ini dilakukan untuk mengetahui aktivitas dari ekstrak daun sungkai (Peronema canescens Jack.) yang memiliki senyawa flavonoid terhadap pertumbuhan dari probiotik Lactobacillus plantarum. Campuran dari ekstrak daun sungkai dan probiotik L. plantarum yang memiliki metabolit sekunder masing-masing diharapkan dapat menghambat bakteri Escherichia coli dengan lebih baik. Uji antibakteri di…
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- xix, 136 hlm.; ilus.; 29 cm
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- T952402023
OPTIMASI ORALLY DISSOLVING FILM (ODF) ASAM USNAT DENGAN POLIMER PVP K-30 MENG…
Asam usnat adalah komponen kimia umum yang ditemukan dalam sel lumut dan merupakan komponen kimia dari temuan utama metabolit pada semua spesies Usnea sp. Penggunaan asam usnat sebagai obat masih terbatas karena kelarutannya yang kurang baik dalam air dan termasuk kedalam BCS kelas II. PVP digunakan sebagai pelarut dalam sediaan oral dan sediaan parenteral, dan telah terbukti telah meningkatkan…
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- xv, 63 hlm.; ilus.; 29 cm
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- T1296742023
UJI AKTIVITAS HEPATOPROTEKTOR EKSTRAK ETANOL DAUN GAMAL (GLIRICIDIA SEPIUM) P…
Gamal leaves (Gliricidia sepium) contain several secondary metabolites, considered efficacious as hepatoprotector. This study aims to determine the activity of the ethanol extract of Gamal leaves as a hepatoprotector by measuring levels of SGPT, SGOT and ALP and liver histopathology of Wistar male white rats. Mice were divided into six groups: normal group (0.5% Na CMC suspension), positive gro…
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- xvi, 49 hlm.; ilus.; 29 cm
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- T947432023
UJI AKTIVITAS ANTIOKSIDAN FIKOSIANIN DARI MIKROALGA SPIRULINA PLATENSIS SECAR…
One source of antioxidants is phycocyanin from the microalga Spirulina platensis which has pharmacological activity as a natural antioxidant. This study aims to determine the antioxidant activity of phycocyanin from Spirulina platensis microalgae in vitro using the DPPH and FRAP methods. Based on the results of this study, the antioxidant activity of the positive control of vitamin C have IC50 …
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- xx, 30 hlm.; ilus.; 29 cm
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- T1054072023
OPTIMASI SEDIAAN SUNSCREEN SPRAY GEL EKSTRAK ETANOL DAUN ALPUKAT (Persea amer…
KIN THAT IS EXPOSED TO EXCESSIVE SUN EXPOSURE CAN RESULT IN SEVERAL LOSSES THAT CAN DAMAGE THE SKIN INCLUDING PREMATURE AGING, SKIN DAMAGE BY ULTRAVIOLET RADIATION, AND SUNBURN OR BURNING REACTIONS. SUNSCREEN IS NEEDED TO PROTECT THE SKIN FROM DAMAGE CAUSED BY UV RAYS. ZINC OXIDE IS A PHYSICAL SUNSCREEN AGENT THAT IS OFTEN USED AS AN ACTIVE INGREDIENT IN SUNSCREEN PREPARATIONS. AVOCADO LEAVES H…
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- xvii, 122 hlm.; ilus.; 29 cm
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- T951332023
FORMULASI DAN UJI AKTIVITAS ANTIERITEMA GEL TABIR SURYA EKSTRAK ETIL ASETAT D…
Breadfruit leaves (Artocarpus altilis (Park.) Fosberg) are reported to contain flavonoids which have activity as photoprotective agents due to their ability to absorb UV light. This study aims to determine the effect of various extracts on the effect of the anti-erythema activity test of sunscreen gel with HPMC carrier. Sunscreen gels were made with ethyl acetate extract of breadfruit leaves us…
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- xv, 63 hlm.; ilus.; 29 cm
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- T1316742023
OPTIMASI GELLING AGENT PADA SEDIAAN GEL EKSTRAK SAMBILOTO (ANDROGRAPHIS PANIC…
Daun sambiloto (Andrographis paniculata (Burm.f.) Nees) merupakan tanaman yang mengandung senyawa aktif seperti andrografolida (diterpenlactone), flavonoid, asam quinic, steroid, saponin, alkaloid dan tanin yang memiliki potensi sebagai antiinflamasi, antioksidan, antibakteri, dan mempercepat penyembuhan luka. Penelitian ini bertujuan untuk mengoptimasi Gelling Agent pada sediaan gel ekstrak sa…
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- viii, 124 hlm.; ilus.; 29 cm
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- T944322023
FORMULASI DAN EVALUASI SPRAY GEL CHITOOLIGOSACCHRIDE SEBAGAI ANTI JERAWAT TER…
Chitooligosacchride is a complex compound of the glycoprotein group which has a 1,4 glucosamine bond. Chitooligosaccharide as a natural cationic antibacterial agent is widely believed to occur because it interacts and disrupts the structure of the cell wall or cell membrane. This study aims to determine the effect of variations of chitooligosacchride as an anti-acne against Propionibacterium ac…
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- xix, 67 hlm.; ilus.; 29 cm
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- T949432023
OPTIMASI ORALLY DISSOLVING FILM (ODF) ASAM USNAT DENGAN POLIMER PULLULAN MENG…
Asam usnat dapat ditemukan pada lumut, dan terutama melimpah seperti pada genus Alectia, Cladonia, Usnea, Lecanora, Ramalina dan Evernia. Banyak lumut dan ekstrak yang mengandung asam usnat telah digunakan untuk kosmetik dan pengobatan. Asam usnat masih terbilang jarang digunakan dalam pengobatan dikarenakan termasuk dalam BCS kelas II dan tergolong praktis tidak larut dalam air. Pembuatan Oral…
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- xvi, 63 hlm.; ilus.; 29 cm
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- T1296792023
ANALISIS PERENCANAAN OBAT DI 4 PUSKESMAS DI KOTA PALEMBANG TAHUN 2022
ABSTRACT Drug planning determines the type and amount of drugs aimed at implementing rational drug use and increasing the efficiency of drug use. However, patients often complain about the availability of drugs at the Health Center because of vacancies. This is due to the inaccuracy of drug planning and procurement. This study aimed to analyze drug procurement at the Palembang City Health Cente…
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- xviii, 137 hlm.; ilus.; 29 cm
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- T1045322023
PENGARUH EKSTRAK ETIL ASETAT DAUN SUKUN (Artocarpus altilis) TERHADAP PERBAIK…
Daun sukun (artocarpus altilis) dilaporkan memiliki kandungan flavonoid yang memiliki aktivitas antioksidan dan antiinflamasi yang berpotensi memperbaiki fungsi ginjal. Penelitian ini bertujuan untuk mengetahui pengaruh variasi dosis terhadap efek nefroprotektif. Parameter yang diamati meliputi volume urin, pH urin, kreatinin serum, ureum serum, protein urin, klirens kreatinin, serta dilakukan …
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- xviii, 137 hlm.; ilus.; 29 cm
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- T1044922023
FORMULASI DAN UJI AKTIVITAS ANTIDIABETES NANOSUSPENSI EKSTRAK DAUN KENIKIR (C…
Kenikir leaves has pharmacological activity as an antidiabetic because it contains flavonoid compounds in the form of quersetin which can become the α-glukosidase enzyme inhibitor so that excess blood glucose level can be lowered. The effectiveness and bioavailability of extracts tend to be low so that the formula in the form of nanosuspension is an option for improving the delivery system whi…
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- xviii, 86 hlm.; ilus.; 29 cm
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- T1057122023
EVALUASI MIKROANATOMI GINJAL PEMBERIAN SELF NANO EMULSION (SNE) EKSTRAK TEH P…
White tea has pharmacological activity as an antidiabetic because it contains polyphenol compounds in the form of epigallocatechin gallate (EGCG) which can inhibit the α-glucosidase enzyme so that blood glucose levels can be returned within normal limits. However, plant extracts have low oral bioavailability, so the formula in the form of SNEDDS (Self-Nano Emulsifying Drug Delivery Systems) is…
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- x, 97 hlm.; ilus.; 29 cm
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- T930412023
UJI AKTIVITAS ANTIOKSIDAN KOMBINASI EKSTRAK ETANOL DAUN SIRSAK (Annona murica…
Soursop leaf and sapodilla leaf contain secondary metabolit is flavonoid which is antioxidant. The study aimed to the characteristic of the ethanol extract soursop leaf (Annona muricata L.) and sapodilla leaf (Manilkara zapota L.), total flavonoid contents, and antioxidant activity of combine ethanol extract soursoup leaf and sapodilla leaf using DPPH method. The treatment of antioxidant activi…
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- xix, 71 hlm.; ilus.; 29 cm
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- T1056172023
UJI AKTIVITAS ANTIOKSIDAN FRAKSI ETIL ASETAT DAUN BELUNTAS (Pluchea indica L.…
Daun beluntas (Pluchea indica L.) mengandung metabolit sekunder seperti flavonoid yang berpotensi sebagai antioksidan. Tujuan penelitian ini adalah untuk mengetahui karakterisasi, jumlah kadar flavonoid total, dan pengaruh pemberian fraksi etil asetat daun beluntas terhadap kadar MDA, aktivitas enzim katalase, gambaran makroskopik dan histopatologi hepar tikus yang diinduksi CCl4, serta mengeta…
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- xviii, 73 hlm.; ilus.; 29 cm
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- T954322023
FORMULASI DISPERSI PADAT AZITROMISIN DENGAN POLYETILEN GLIKOL (PEG) 6000 DAN …
Azitromisin mempunyai sifat sebagai antibiotik turunan makrolida, namun memiliki kelarutan yang rendah dalam air. Sehingga dikelompokkan kedalam sistem klasifikasi biofarmasetika (BCS) kelas II. Berbagai cara telah dilakukan untuk meningkatkan laju disolusi, salah satunya dengan dispersi padat. Dispersi padat adalah campuran yang terdiri dari satu atau lebih zat aktif dalam pembawa yang bersifa…
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- xix, 76 hlm.; ilus.; 29 cm
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- T1050382023
ANALISIS HUBUNGAN PENGGUNAAN OBAT ANTIPSIKOTIK TERHADAP KEJADIAN EFEK SAMPING…
Skizofrenia merupakan salah satu ganggu jiwa berat yang ditandai dengan kesulitan pada penderita untuk membedakan antara nyata dan tidak nyata dalam kehidupan sehari-hari seperti halusinasi dan delusi. Manajemen terapi yang digunakan pada pasien skizofrenia adalah menggunakan terapi antipsikotik. Efek samping yang sering muncul akibat terapi antipsikotik adalah gejala ekstrapiramidal. Penelitia…
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- xv, 150 hlm.; ilus.; 29 cm
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- T942542023
HUBUNGAN RASIONALITAS PENGGUNAAN OBAT TERHADAP OUTCOME KLINIS PASIEN GOUT DI …
Gout is an arthritis disease that occurs due to increased levels of uric acid in the blood (hyperuricemia), causing the deposition of monosodium urate (MSU) crystals in the joints. Rational drug use in gout patients can affect the success of therapy. This study aims to determine the correlation between the rationality of drug use and clinical outcomes in gout patients at RSI Siti Khadijah Palem…
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- xix, 117 hlm.; ilus.; 29 cm
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- T1011272023
UJI AKTIVITAS ANTIOKSIDAN SERTA PENGUKURAN KANDUNGAN FENOLIK DAN KAROTENOID D…
Microalgae Chlorella sp. contains phenolic secondary metabolites and carotenoids which have antioxidant activity. Previous studies reported that many of the chemical components of Chlorella such as phenolic compounds, β-carotene, ascorbic acid and tocopherols exhibit antioxidant properties. In this study the aim was to measure the phenolic and carotenoid content of the microalgae Chlorella sp.…
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- xvii, 99 hlm.; ilus.; 29 cm
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- T1055892023
PREPARASI DAN KARAKTERISASI FORMULA DISPERSI PADAT AZITROMISIN-PVA (POLYVINYL…
Azitromisin adalah antibiotik golongan makrolida yang termasuk ke dalam BCS (Biopharmaceutical Classification System) kelas II, yang memiliki kelarutan buruk, bioavailabilitas oral yang buruk, dan permeabilitas yang tinggi. Pembuatan dispersi padat Azitromisin dilakukan dengan menggunakan teknik kokristalisasi menggunakan metode bead milling (penggilingan) yang dilakukan dengan tujuan memperkec…
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- xvii, 94 hlm.; ilus.; 29 cm
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- T942972023
PENGARUH EKSTRAK ETIL ASETAT DAUN NANGKA (Artocarpus heterophyllus) TERHADAP …
Ekstrak etil asetat daun nangka (Artocarpus heterophyllus) mengandung senyawa metabolit sekunder berupa flavonoid yang memiliki aktivitas antioksidan dan antiinflamasi yang berpotensi memperbaiki fungsi ginjal. Penelitian ini bertujuan mengetahui aktivitas perbaikan fungsi ginjal dari ekstrak etil asetat daun nangka (EEADN). Uji aktivitas perbaikan ginjal dilakukan selama 28 hari menggunakan 30…
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- xviii, 138 hlm.; ilus.; 29 cm
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- T1044932023
EVALUASI PENGGUNAAN ANTIBIOTIK PADA PASIEN ANAK DEMAM TIFOID DI RSUD DR.H.M. …
Typhoid fever is an acute systemic infectious disease caused by Salmonella typhi which is transmitted via fecal and oral routes and is treated with antibiotics. The purpose of this study was to determine patient characteristics, patterns of antibiotic use and the DDD/100 patient-days value of typhoid fever pediatric patients at Dr.H.Moh Rabain Muara Enim General Hospital. This research is a des…
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- xvii, 102 hlm.; ilus.; 29 cm
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- T1286312023
EVALUASI PENGGUNAAN OBAT ANTIPLATELET TERHADAP PASIEN STROKE ISKEMIK DI RUMAH…
Ischemic stroke is a stroke caused by a blood clot or embolism blocking a cerebral artery. Ischemic stroke occurs in almost 70-85% of cases and is the most common type of stroke. This ischemic stroke disease can be given antiplatelet drug therapy with a mechanism of action in the form of inhibiting platelet aggregation. The use of antiplatelet drugs needs to be investigated to know whether it w…
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- xxi, 213 hlm.; ilus.; 29 cm
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- T1014052023
FORMULASI DAN EVALUASI MASKER PEEL-OFF GEL CHITOLIGOSACCHARIDE SEBAGAI ANTI J…
Chitooligosaccaharide adalah senyawa turunan dari kitosan hasil proses deasetilasi kitin dan senyawa kompleks golongan glikoprotein yang memiliki ikatan 1,4 glukosamin mampu bersifat antimikroba. Penelitian ini bertujuan mengetahui variasi konsentrasi chitooligosaccharide sebagai antijerawat terhadap bakteri Propionibacterium acnes hasil tersebut dianalisa menggunakan Program SPSS®.Variasi kon…
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- xviii, 93 hlm.; ilus.; 29 cm
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- T949412023
EVALUASI PENGGUNAAN OBAT ASMA PADA PASIEN ASMA DI INSTALASI RAWAT INAP RUMAH …
Asthma is a chronic inflammatory disease of the respiratory tract that causes bronchial hyperactivity to various stimuli, both directly and indirectly. Asthma is included in te top ten causes morbidity and mortality in Indonesia. This study aims to determine the accuracy of using asthma drug in asthma patients at the Inpatient Installation of the Siti Khadijah Islamic Hospital Palembang for the…
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- xviii, 113 hlm.; ilus.; 29 cm
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- T1039972023
FORMULASI DAN UJI AKTIVITAS ANTIERITEMA GEL TABIR SURYA EKSTRAK ETIL ASETAT D…
Breadfruit leaves (Artocarpus altilis (Park.) Fosberg) contain flavonoids which have activity and have the potential to act as photoprotective agents because of their ability to absorb UV light. This study aims to determine the effect of variations in the formulation of breadfruit leaf ethyl acetate extract on the effect of activity tests as a sunscreen with Carbomer 940 and Triethanolamine as …
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- xiii, 93 hlm.; ilus.; 29 cm
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- T1317882023
FORMULASI DAN UJI AKTIVITAS ANTIERITEMA KRIM TABIR SURYA EKSTRAK ETIL ASETAT …
Exposure to direct sunlight for a long time can cause damage to the epidermal tissue of the skin which is a factor in the emergence of erythema and causes skin cancer. Sunscreen is a cosmetic product that functions to protect the skin from exposure to UV rays. Breadfruit leaves (Artocarpus altilis) are reported to contain antioxidant compounds which have the potential to be active ingredients f…
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- xvii, 93 hlm.; ilus.; 29 cm
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- T1317772023
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